Determination of colistin resistance in Escherichia coli isolates from foods in Turkey, 2011-2015

Mustafa Guzel; M. Dilek Avsaroglu; Yeşim Soyer

EN

Determination of colistin resistance in Escherichia coli isolates from foods in Turkey, 2011-2015

Abstract

Antimicrobial resistance of pathogenic microorganisms is an emerging public health concern. Intensive use of antibiotics in food animals might increase antimicrobial resistance in foodborne pathogens. Colistin is a last resort antibiotic for treatment of multidrug resistant (MDR) Gram negative pathogens. The recent antimicrobial resistance studies revealed a mobile antimicrobial resistance gene (mcr) that provides resistance to colistin. Furthermore, the gene has been found in different genera. Therefore, the aim of this study was to determine colistin resistance of Escherichia coli isolates (N=48) isolated in between 2011 and 2015 from food samples in Turkey. In addition, 5 mcr genes and their variants were screened by performing PCR on resistant isolates. 4 E. coli isolates were found resistant to colistin above the epidemiological cut-off value (Minimum inhibitory concentration (MIC) > 2mg/L). None of the resistant isolates had the mcr genes. Further studies with human and food isolates should be conducted to figure out which gene or genes are responsible for colistin resistance.

Keywords

References

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Details

Primary Language

English

Subjects

Food Engineering

Journal Section

Research Article

Authors

Mustafa Guzel
0000-0002-4750-7488
Türkiye

M. Dilek Avsaroglu
Türkiye

Yeşim Soyer ^*
0000-0001-9687-9715
Türkiye

Publication Date

May 16, 2020

Submission Date

November 15, 2019

Acceptance Date

March 7, 2020

Published in Issue

Year 1970 Volume: 6 Number: 3

IZ

https://izlik.org/JA48YN83ML

Cite

RIS / Bibtex

APA

Guzel, M., Avsaroglu, M. D., & Soyer, Y. (2020). Determination of colistin resistance in Escherichia coli isolates from foods in Turkey, 2011-2015. Food and Health, 6(3), 160-169. https://izlik.org/JA48YN83ML