Year 2019, Volume 5, Issue 1, Pages 39 - 47 2019-01-01

EVALUATION OF ANTIOXIDANT AND CHOLINESTERASE INHIBITORY ACTIVITIES OF SOME MEDICINAL PLANTS

Ezgican Ulaç [1] , Pelin Köseoğlu Yılmaz [2] , Ufuk Kolak [3]

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The aim of this study was to determine total phenolic and total flavonoid contents, antioxidant and anticholinesterase activities of the hexane, acetone and ethanol extracts prepared from mantle, rosemary, thistle, mallow and nettle commonly consumed for medicinal and nutraceutical purposes in Turkey and all around the world. DPPH free radical, ABTS cation radical and superoxide anion radical scavenging assays, and Ellman method were used to establish the antioxidant and anticholinesterase potential of the extracts, respectively. Total phenolic and total flavonoid contents of the mantle ethanol extract were found to be the richest extract among the others. Mantle ethanol and thistle hexane extracts in DPPH free radical scavenging method (88.03% and 88.07%, respectively), and acetone and ethanol extracts of mantle and rosemary in ABTS cation radical scavenging assay showed the highest inhibition (88.60% and 89.73%, respectively) at 100 μg/mL concentration. None of the extracts exhibited superoxide anion radical scavenging activity. Nettle ethanol extract indicated higher butyrylcholinesterase inhibitory activity (92.68%) than galanthamine, mallow acetone extract as galanthamine, mantle hexane, mallow hexane and ethanol, and nettle acetone extracts almost as galanthamine. To our knowledge, ABTS cation radical and superoxide anion radical scavenging activities, and anticholinesterase potential of the extracts prepared from mantle leaves and flowers, anticholinesterase effect of thistle seeds extracts, ABTS cation radical scavenging activity and butyrylcholinesterase inhibitory activity of the extracts prepared from mallow leaves and flowers were investigated for the first time in this study.

Medicinal Plant, Total Phenolic, Total Flavonoid, Antioxidant, Anticholinesterase
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Primary Language en
Subjects Biology
Journal Section Research Articles
Authors

Orcid: 0000-0002-5863-2962
Author: Ezgican Ulaç
Institution: Department of Analytical Chemistry, Faculty of Pharmacy, Istanbul University
Country: Turkey


Orcid: 0000-0002-9871-1710
Author: Pelin Köseoğlu Yılmaz
Institution: Department of Analytical Chemistry, Faculty of Pharmacy, Istanbul University
Country: Turkey


Orcid: 0000-0002-0339-635X
Author: Ufuk Kolak (Primary Author)
Institution: Department of Analytical Chemistry, Faculty of Pharmacy, Istanbul University
Country: Turkey


Dates

Publication Date: January 1, 2019

Bibtex @research article { jfhs381277, journal = {FOOD and HEALTH}, issn = {}, eissn = {2602-2834}, address = {ScientificWebJournals}, year = {2019}, volume = {5}, pages = {39 - 47}, doi = {10.3153/FH19005}, title = {EVALUATION OF ANTIOXIDANT AND CHOLINESTERASE INHIBITORY ACTIVITIES OF SOME MEDICINAL PLANTS}, key = {cite}, author = {Ulaç, Ezgican and Köseoğlu Yılmaz, Pelin and Kolak, Ufuk} }
APA Ulaç, E , Köseoğlu Yılmaz, P , Kolak, U . (2019). EVALUATION OF ANTIOXIDANT AND CHOLINESTERASE INHIBITORY ACTIVITIES OF SOME MEDICINAL PLANTS. FOOD and HEALTH, 5 (1), 39-47. DOI: 10.3153/FH19005
MLA Ulaç, E , Köseoğlu Yılmaz, P , Kolak, U . "EVALUATION OF ANTIOXIDANT AND CHOLINESTERASE INHIBITORY ACTIVITIES OF SOME MEDICINAL PLANTS". FOOD and HEALTH 5 (2019): 39-47 <http://jfhs.scientificwebjournals.com/issue/38141/381277>
Chicago Ulaç, E , Köseoğlu Yılmaz, P , Kolak, U . "EVALUATION OF ANTIOXIDANT AND CHOLINESTERASE INHIBITORY ACTIVITIES OF SOME MEDICINAL PLANTS". FOOD and HEALTH 5 (2019): 39-47
RIS TY - JOUR T1 - EVALUATION OF ANTIOXIDANT AND CHOLINESTERASE INHIBITORY ACTIVITIES OF SOME MEDICINAL PLANTS AU - Ezgican Ulaç , Pelin Köseoğlu Yılmaz , Ufuk Kolak Y1 - 2019 PY - 2019 N1 - doi: 10.3153/FH19005 DO - 10.3153/FH19005 T2 - FOOD and HEALTH JF - Journal JO - JOR SP - 39 EP - 47 VL - 5 IS - 1 SN - -2602-2834 M3 - doi: 10.3153/FH19005 UR - https://doi.org/10.3153/FH19005 Y2 - 2018 ER -
EndNote %0 FOOD and HEALTH EVALUATION OF ANTIOXIDANT AND CHOLINESTERASE INHIBITORY ACTIVITIES OF SOME MEDICINAL PLANTS %A Ezgican Ulaç , Pelin Köseoğlu Yılmaz , Ufuk Kolak %T EVALUATION OF ANTIOXIDANT AND CHOLINESTERASE INHIBITORY ACTIVITIES OF SOME MEDICINAL PLANTS %D 2019 %J FOOD and HEALTH %P -2602-2834 %V 5 %N 1 %R doi: 10.3153/FH19005 %U 10.3153/FH19005
ISNAD Ulaç, Ezgican , Köseoğlu Yılmaz, Pelin , Kolak, Ufuk . "EVALUATION OF ANTIOXIDANT AND CHOLINESTERASE INHIBITORY ACTIVITIES OF SOME MEDICINAL PLANTS". FOOD and HEALTH 5 / 1 (January 2019): 39-47. https://doi.org/10.3153/FH19005
AMA Ulaç E , Köseoğlu Yılmaz P , Kolak U . EVALUATION OF ANTIOXIDANT AND CHOLINESTERASE INHIBITORY ACTIVITIES OF SOME MEDICINAL PLANTS. Food Health. 2019; 5(1): 39-47.
Vancouver Ulaç E , Köseoğlu Yılmaz P , Kolak U . EVALUATION OF ANTIOXIDANT AND CHOLINESTERASE INHIBITORY ACTIVITIES OF SOME MEDICINAL PLANTS. FOOD and HEALTH. 2019; 5(1): 47-39.