Cilt 4, Sayı 1, Sayfalar 19 - 24 2017-11-06

Nigella sativa OIL COULD INDUCE OSTEOGENIC DIFFERENTIATION OF DENTAL PULP MESENCHYMAL STEM CELLS: CLINICAL NUTRITION FOR DENTISTRY

Ayşegül Mendi [1]

20 54

A natural agent that, promotes osteogenic differentiation of dental pulp mesenchymal stem cells (DP-MSCs) could achieve success in regeneration during healing and may also prevent bone resorption and improve regeneration. We aimed to demonstrate that a Nigella sativa oil could induce differentiation of DP-MSCs. DP-MSCs were isolated from 3. molars and identified with flow cytometer. Osteogenic differentiation was conducted, and calcium granules were showed by typical Alizarin Red dying and calcium concentration were determined by DICA 500. Identification results showed that the cells are mesenchymal stem cells. Alizarin Red dying signed the calcium granules and DICA 500 showed that calcium concentrations were higher than the Control Group. This preliminary study shows for the first time the inductive potential of N. sativa oil for osteogenic differentiation in DP-MSCs. The mechanism should be investigated in further studies. 

Dental pulp mesenchymal stem cells,Nigella sativa,Osteogenic differentiation,Dexamethosone
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Dergi Bölümü Makaleler
Yazarlar

Orcid: 0000-0001-6705-3770
Yazar: Ayşegül Mendi
E-posta: aysegulmendi@gmail.com
Kurum: Gazi University Faculty of Dentistry, Department of Medical Microbiology, Emek Ankara
Ülke: Turkey


Bibtex @araştırma makalesi { jfhs349685, journal = {Food and Health}, issn = {}, address = {Özkan ÖZDEN}, year = {2017}, volume = {4}, pages = {19 - 24}, doi = {10.3153/JFHS18003}, title = {Nigella sativa OIL COULD INDUCE OSTEOGENIC DIFFERENTIATION OF DENTAL PULP MESENCHYMAL STEM CELLS: CLINICAL NUTRITION FOR DENTISTRY}, language = {en}, key = {cite}, author = {Mendi, Ayşegül} }
APA Mendi, A . (2017). Nigella sativa OIL COULD INDUCE OSTEOGENIC DIFFERENTIATION OF DENTAL PULP MESENCHYMAL STEM CELLS: CLINICAL NUTRITION FOR DENTISTRY. Food and Health, 4 (1), 19-24. DOI: 10.3153/JFHS18003
MLA Mendi, A . "Nigella sativa OIL COULD INDUCE OSTEOGENIC DIFFERENTIATION OF DENTAL PULP MESENCHYMAL STEM CELLS: CLINICAL NUTRITION FOR DENTISTRY". Food and Health 4 (2017): 19-24 <http://jfhs.scientificwebjournals.com/issue/31825/349685>
Chicago Mendi, A . "Nigella sativa OIL COULD INDUCE OSTEOGENIC DIFFERENTIATION OF DENTAL PULP MESENCHYMAL STEM CELLS: CLINICAL NUTRITION FOR DENTISTRY". Food and Health 4 (2017): 19-24
RIS TY - JOUR T1 - Nigella sativa OIL COULD INDUCE OSTEOGENIC DIFFERENTIATION OF DENTAL PULP MESENCHYMAL STEM CELLS: CLINICAL NUTRITION FOR DENTISTRY AU - Ayşegül Mendi Y1 - 2017 PY - 2017 N1 - doi: 10.3153/JFHS18003 DO - 10.3153/JFHS18003 T2 - Food and Health JF - Journal JO - JOR SP - 19 EP - 24 VL - 4 IS - 1 SN - -2602-2834 M3 - doi: 10.3153/JFHS18003 UR - http://dx.doi.org/10.3153/JFHS18003 Y2 - 2017 ER -
EndNote %0 Food and Health Nigella sativa OIL COULD INDUCE OSTEOGENIC DIFFERENTIATION OF DENTAL PULP MESENCHYMAL STEM CELLS: CLINICAL NUTRITION FOR DENTISTRY %A Ayşegül Mendi %T Nigella sativa OIL COULD INDUCE OSTEOGENIC DIFFERENTIATION OF DENTAL PULP MESENCHYMAL STEM CELLS: CLINICAL NUTRITION FOR DENTISTRY %D 2017 %J Food and Health %P -2602-2834 %V 4 %N 1 %R doi: 10.3153/JFHS18003 %U 10.3153/JFHS18003