BESİN KARSİNOJENLERİNİN DETOKSİFİKASYONUNDA ALTERNATİF YÖNTEM: PROBİYOTİKLER

Sümeyra Sevim; Mevlüde Kızıl

doi:10.3153/FH19015

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BESİN KARSİNOJENLERİNİN DETOKSİFİKASYONUNDA ALTERNATİF YÖNTEM: PROBİYOTİKLER

Öz

Besin hazırlama ve pişirmede kullanılan geleneksel ısıl işlemler (örneğin kızartma, fırınlama) besinin güvenilirliğini ve tüketilebilirliğini artırmak için yapılan uygulamalardır. Bununla birlikte, bu ısıl işlemler protein denatürasyonu, karbonhidratların çözünürlüğünde değişiklikler, vitamin bozunması ve yağ oksidasyonu yoluyla son ürünün kalitesinde bozulmaya neden olabilmekte ve çeşitli potansiyel zararlı bileşikler oluşabilmektedir. Bunlar içerisinden heterosiklik aromatik aminler, akrilamid ve polisiklik aromatik hidrokarbonların birçok çalışmada karsinojenik ve genotoksik nitelikte oldukları ispatlanmıştır. Bu karsinojenik bileşikleri ortadan kaldırmak için çeşitli fiziksel ya da kimyasal yöntemler olmasına rağmen bu yöntemlerin yeterince etkin kullanılmaması insan sağlığı için güvenilir ve başarılı alternatif yöntemlere ihtiyacı ortaya çıkarmıştır. Yararlı mikroorganizmalar olarak bilinen probiyotik bakterilerin antikarsinojenik etkileri ve hücre duvarı yapısından kaynaklı bağlanma yeteneklerinden yola çıkılarak diyet mutajenlerine bağlanabileceği ve bu şekilde detoksifiye (toksik etkileri yok etme) edebileceği üzerinde durulmaktadır. Bu derlemede de probiyotik bakterilerin besinlerde ısıl işlem sonucu oluşan karsinojenik bileşikler üzerindeki detoksifiye edici etkisini inceleyen araştırmalar değerlendirilmiştir.

Anahtar Kelimeler

Heterosiklik aromatik aminler,Akrilamid,Polisiklik aromatik hidrokarbonlar,Probiyotikler,Karsinojenler

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Details

Primary Language

Turkish

Subjects

Food Engineering

Journal Section

Review

Authors

Sümeyra Sevim
0000-0001-9724-2628
Türkiye

Mevlüde Kızıl ^*
0000-0003-1380-3243
Türkiye

Publication Date

July 1, 2019

Submission Date

November 15, 2018

Acceptance Date

December 4, 2018

Published in Issue

Year 1970 Volume: 5 Number: 3

DOI

https://doi.org/10.3153/FH19015

IZ

https://izlik.org/JA98CJ49HK

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Sevim, S., & Kızıl, M. (2019). BESİN KARSİNOJENLERİNİN DETOKSİFİKASYONUNDA ALTERNATİF YÖNTEM: PROBİYOTİKLER. Food and Health, 5(3), 139-148. https://doi.org/10.3153/FH19015

AN ALTERNATIVE METHOD IN DETOXIFICATION OF FOOD CARCINOGENES: PROBIOTICS

BESİN KARSİNOJENLERİNİN DETOKSİFİKASYONUNDA ALTERNATİF YÖNTEM: PROBİYOTİKLER

Öz

Anahtar Kelimeler

AN ALTERNATIVE METHOD IN DETOXIFICATION OF FOOD CARCINOGENES: PROBIOTICS

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