Year 2019, Volume 5 , Issue 3, Pages 139 - 148 2019-07-01

AN ALTERNATIVE METHOD IN DETOXIFICATION OF FOOD CARCINOGENES: PROBIOTICS
BESİN KARSİNOJENLERİNİN DETOKSİFİKASYONUNDA ALTERNATİF YÖNTEM: PROBİYOTİKLER

Sümeyra Sevim [1] , Mevlüde Kızıl [2]


Traditional heat treatments (eg frying, baking) used in food preparation and cooking are applications to improve the reliability and consumption of food. However, these thermal processes can lead to deterioration in the quality of the final product by protein denaturation, changes in the solubility of carbohydrates, vitamin degradation, and fat oxidation, and various potentially harmful compounds can occur unintentionally. Among them, heterocyclic aromatic amines, acrylamide and polycyclic aromatic hydrocarbons have proved to be carcinogenic and genotoxic in many studies. Although there are various physical or chemical methods to eliminate these carcinogenic compounds, the ineffective use of these methods has created the need for safe and successful alternative methods for human health. It is emphasized that probiotic bacteria, known as beneficial microorganisms, can bind to the diet mutagens based on their anticarcinogenic effects and binding ability from the cell wall structure and in this way it is thought to detoxify (eliminate toxic effects) them. In this review, the studies investigating the detoxification effect of probiotic bacteria on carcinogenic compounds resulting from heat treatment in foods are evaluated.

Besin hazırlama ve pişirmede kullanılan geleneksel ısıl işlemler (örneğin kızartma, fırınlama) besinin güvenilirliğini ve tüketilebilirliğini artırmak için yapılan uygulamalardır.  Bununla birlikte, bu ısıl işlemler protein denatürasyonu, karbonhidratların çözünürlüğünde değişiklikler, vitamin bozunması ve yağ oksidasyonu yoluyla son ürünün kalitesinde bozulmaya neden olabilmekte ve çeşitli potansiyel zararlı bileşikler oluşabilmektedir. Bunlar içerisinden heterosiklik aromatik aminler, akrilamid ve polisiklik aromatik hidrokarbonların birçok çalışmada karsinojenik ve genotoksik nitelikte oldukları ispatlanmıştır. Bu karsinojenik bileşikleri ortadan kaldırmak için çeşitli fiziksel ya da kimyasal yöntemler olmasına rağmen bu yöntemlerin yeterince etkin kullanılmaması insan sağlığı için güvenilir ve başarılı alternatif yöntemlere ihtiyacı ortaya çıkarmıştır. Yararlı mikroorganizmalar olarak bilinen probiyotik bakterilerin antikarsinojenik etkileri ve hücre duvarı yapısından kaynaklı bağlanma yeteneklerinden yola çıkılarak diyet mutajenlerine bağlanabileceği ve bu şekilde detoksifiye (toksik etkileri yok etme) edebileceği üzerinde durulmaktadır. Bu derlemede de probiyotik bakterilerin besinlerde ısıl işlem sonucu oluşan karsinojenik bileşikler üzerindeki detoksifiye edici etkisini inceleyen araştırmalar değerlendirilmiştir.

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Primary Language tr
Subjects Food Science and Technology
Journal Section Review
Authors

Orcid: 0000-0001-9724-2628
Author: Sümeyra Sevim
Institution: Hacettepe Üniversitesi Sağlık Bilimleri Fakültesi Beslenme ve Diyetetik Bölümü, Bölümü Toplu Beslenme Sistemleri Ana Bilim Dalı, Ankara
Country: Turkey


Orcid: 0000-0003-1380-3243
Author: Mevlüde Kızıl (Primary Author)
Institution: Hacettepe Üniversitesi Sağlık Bilimleri Fakültesi Beslenme ve Diyetetik Bölümü, Bölümü Toplu Beslenme Sistemleri Ana Bilim Dalı Ankara
Country: Turkey


Dates

Publication Date : July 1, 2019

Bibtex @review { jfhs483026, journal = {Food and Health}, issn = {}, eissn = {2602-2834}, address = {Vidin Caddesi No:28 D:4 Kocamustafapaşa 34107 Fatih İstanbul}, publisher = {ScientificWebJournals}, year = {2019}, volume = {5}, pages = {139 - 148}, doi = {10.3153/FH19015}, title = {BESİN KARSİNOJENLERİNİN DETOKSİFİKASYONUNDA ALTERNATİF YÖNTEM: PROBİYOTİKLER}, key = {cite}, author = {Sevim, Sümeyra and Kızıl, Mevlüde} }
APA Sevim, S , Kızıl, M . (2019). BESİN KARSİNOJENLERİNİN DETOKSİFİKASYONUNDA ALTERNATİF YÖNTEM: PROBİYOTİKLER. Food and Health , 5 (3) , 139-148 . DOI: 10.3153/FH19015
MLA Sevim, S , Kızıl, M . "BESİN KARSİNOJENLERİNİN DETOKSİFİKASYONUNDA ALTERNATİF YÖNTEM: PROBİYOTİKLER". Food and Health 5 (2019 ): 139-148 <http://jfhs.scientificwebjournals.com/en/issue/42227/483026>
Chicago Sevim, S , Kızıl, M . "BESİN KARSİNOJENLERİNİN DETOKSİFİKASYONUNDA ALTERNATİF YÖNTEM: PROBİYOTİKLER". Food and Health 5 (2019 ): 139-148
RIS TY - JOUR T1 - BESİN KARSİNOJENLERİNİN DETOKSİFİKASYONUNDA ALTERNATİF YÖNTEM: PROBİYOTİKLER AU - Sümeyra Sevim , Mevlüde Kızıl Y1 - 2019 PY - 2019 N1 - doi: 10.3153/FH19015 DO - 10.3153/FH19015 T2 - Food and Health JF - Journal JO - JOR SP - 139 EP - 148 VL - 5 IS - 3 SN - -2602-2834 M3 - doi: 10.3153/FH19015 UR - https://doi.org/10.3153/FH19015 Y2 - 2018 ER -
EndNote %0 Food and Health BESİN KARSİNOJENLERİNİN DETOKSİFİKASYONUNDA ALTERNATİF YÖNTEM: PROBİYOTİKLER %A Sümeyra Sevim , Mevlüde Kızıl %T BESİN KARSİNOJENLERİNİN DETOKSİFİKASYONUNDA ALTERNATİF YÖNTEM: PROBİYOTİKLER %D 2019 %J Food and Health %P -2602-2834 %V 5 %N 3 %R doi: 10.3153/FH19015 %U 10.3153/FH19015
ISNAD Sevim, Sümeyra , Kızıl, Mevlüde . "BESİN KARSİNOJENLERİNİN DETOKSİFİKASYONUNDA ALTERNATİF YÖNTEM: PROBİYOTİKLER". Food and Health 5 / 3 (July 2019): 139-148 . https://doi.org/10.3153/FH19015
AMA Sevim S , Kızıl M . BESİN KARSİNOJENLERİNİN DETOKSİFİKASYONUNDA ALTERNATİF YÖNTEM: PROBİYOTİKLER. Food Health. 2019; 5(3): 139-148.
Vancouver Sevim S , Kızıl M . BESİN KARSİNOJENLERİNİN DETOKSİFİKASYONUNDA ALTERNATİF YÖNTEM: PROBİYOTİKLER. Food and Health. 2019; 5(3): 148-139.