Yıl 2021, Cilt 7 , Sayı 2, Sayfalar 128 - 137 2021-03-09

Milk is composed of water, proteins, lipids, lactose, vitamins, and minerals. More than 80% of most mammals’ milk proteins are constituted by caseins. Casein is a group of proteins and they are sub-divided into αs1-, αs2-, β- and β-casein families. Among these casein families, -casein is the second most abundant protein. Different mutations in the cow milk β-casein gene led to 12 genetic variants and most common of these are genetic variants A1 and A2. The A1 and A2 variants differ only at amino acid position 67, which is histidine in A1 or proline in A2 milk. This difference in amino acid sequence suggests a conformational change in the secondary structure of the expressed β-casein. Milk that contains A1 β-casein and A2 β-casein are known as A1 milk and A2 milk, respectively. A1 β-casein milk releases an amino acid bioactive peptide called beta-casomorphin-7 (βCM-7) in small intestine. Beta-casomorphin-7 released from A1 β-casein is responsible for many human disorders like type-1 diabetes, autism, schizophrenia, alzheimer’s disease (AD), attention deficit hyperactivity disorder (ADHD), multiple sclerosis (MS) and heart diseases.
A1 Milk, A2 Milk, βCM-7, Casein, Health
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Birincil Dil en
Konular Gıda Bilimi ve Teknolojisi
Bölüm Review Articles

Orcid: 0000-0002-8306-0222
Yazar: Seval ANDİÇ (Sorumlu Yazar)
Ülke: Turkey

Orcid: 0000-0002-8818-9850
Yazar: Rozelin Münevver AYAZ
Ülke: Turkey

Orcid: 0000-0001-6889-9487
Yazar: Şehriban OĞUZ
Ülke: Turkey


Başvuru Tarihi : 25 Mayıs 2020
Kabul Tarihi : 4 Ekim 2020
Yayımlanma Tarihi : 9 Mart 2021

Bibtex @İnceleme makalesi { jfhs742564, journal = {Food and Health}, issn = {}, eissn = {2602-2834}, address = {Vidin Caddesi No:28 D:4 Kocamustafapaşa 34107 Fatih İstanbul}, publisher = {Özkan ÖZDEN}, year = {2021}, volume = {7}, pages = {128 - 137}, doi = {10.3153/FH21014}, title = {A1 Milk and Beta-casomorphin-7}, key = {cite}, author = {Andiç, Seval and Ayaz, Rozelin Münevver and Oğuz, Şehriban} }
APA Andiç, S , Ayaz, R , Oğuz, Ş . (2021). A1 Milk and Beta-casomorphin-7 . Food and Health , 7 (2) , 128-137 . DOI: 10.3153/FH21014
MLA Andiç, S , Ayaz, R , Oğuz, Ş . "A1 Milk and Beta-casomorphin-7" . Food and Health 7 (2021 ): 128-137 <http://jfhs.scientificwebjournals.com/tr/pub/issue/58210/742564>
Chicago Andiç, S , Ayaz, R , Oğuz, Ş . "A1 Milk and Beta-casomorphin-7". Food and Health 7 (2021 ): 128-137
RIS TY - JOUR T1 - A1 Milk and Beta-casomorphin-7 AU - Seval Andiç , Rozelin Münevver Ayaz , Şehriban Oğuz Y1 - 2021 PY - 2021 N1 - doi: 10.3153/FH21014 DO - 10.3153/FH21014 T2 - Food and Health JF - Journal JO - JOR SP - 128 EP - 137 VL - 7 IS - 2 SN - -2602-2834 M3 - doi: 10.3153/FH21014 UR - https://doi.org/10.3153/FH21014 Y2 - 2020 ER -
EndNote %0 Food and Health A1 Milk and Beta-casomorphin-7 %A Seval Andiç , Rozelin Münevver Ayaz , Şehriban Oğuz %T A1 Milk and Beta-casomorphin-7 %D 2021 %J Food and Health %P -2602-2834 %V 7 %N 2 %R doi: 10.3153/FH21014 %U 10.3153/FH21014
ISNAD Andiç, Seval , Ayaz, Rozelin Münevver , Oğuz, Şehriban . "A1 Milk and Beta-casomorphin-7". Food and Health 7 / 2 (Mart 2021): 128-137 . https://doi.org/10.3153/FH21014
AMA Andiç S , Ayaz R , Oğuz Ş . A1 Milk and Beta-casomorphin-7. Food Health. 2021; 7(2): 128-137.
Vancouver Andiç S , Ayaz R , Oğuz Ş . A1 Milk and Beta-casomorphin-7. Food and Health. 2021; 7(2): 128-137.
IEEE S. Andiç , R. Ayaz ve Ş. Oğuz , "A1 Milk and Beta-casomorphin-7", Food and Health, c. 7, sayı. 2, ss. 128-137, Mar. 2021, doi:10.3153/FH21014