Year 2021, Volume 7 , Issue 1, Pages 31 - 38 2020-11-09

In vitro risk assessment of Padina pavonica (Linnaeus) (Brown algae)

Adem GÜNER [1]

Padina pavonica (Linnaeus) Thivy 1960 is a brown algae that is antioxidant, antimicrobial, and anticancer effects and is generally used in soup, salad, and other dishes. However, no studies have been reported on safe consumption in humans to date. For this purpose, this study was conducted to determine the cytotoxic and genotoxic effects of P. pavonica on lymphocytes cultured from human blood. The water extract of P. pavonica was added into culture tubes at various concentrations (0.5-1000 μg/mL). Cytotoxic effects were determined by MTT assay. Antioxidant/oxidant status was evaluated by total antioxidant capacity (TAC) and total oxidative status (TOS) assays. Genotoxic effects were investigated by sister chromatid exchanges and micronucleus assays. Our results showed that P. pavonica had no genotoxic effects, even at higher concentrations. 1000 μg/mL concentration of P. pavonica caused an increase (P<0.05) TOS levels while significantly reducing cell viability. However, low concentrations (50 and 100 μg/mL) significantly increased (P<0.05) TAC levels. In conclusion, P. pavonica can be safely consumed with its non-genotoxic and antioxidant properties in a manner dose-dependent.
Algae, Antioxidant, Genotoxic, Oxidative stress, Padina pavonica
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Primary Language en
Subjects Biology
Journal Section Research Articles

Orcid: 0000-0003-3295-3538
Author: Adem GÜNER (Primary Author)
Institution: Giresun University, Faculty of Science and Art, Department of Biology, Güre, Giresun
Country: Turkey


Application Date : May 12, 2020
Acceptance Date : October 4, 2020
Publication Date : November 9, 2020

Bibtex @research article { jfhs736398, journal = {Food and Health}, issn = {}, eissn = {2602-2834}, address = {Vidin Caddesi No:28 D:4 Kocamustafapaşa 34107 Fatih İstanbul}, publisher = {Özkan ÖZDEN}, year = {2020}, volume = {7}, pages = {31 - 38}, doi = {10.3153/FH21004}, title = {In vitro risk assessment of Padina pavonica (Linnaeus) (Brown algae)}, key = {cite}, author = {Güner, Adem} }
APA Güner, A . (2020). In vitro risk assessment of Padina pavonica (Linnaeus) (Brown algae) . Food and Health , 7 (1) , 31-38 . DOI: 10.3153/FH21004
MLA Güner, A . "In vitro risk assessment of Padina pavonica (Linnaeus) (Brown algae)" . Food and Health 7 (2020 ): 31-38 <>
Chicago Güner, A . "In vitro risk assessment of Padina pavonica (Linnaeus) (Brown algae)". Food and Health 7 (2020 ): 31-38
RIS TY - JOUR T1 - In vitro risk assessment of Padina pavonica (Linnaeus) (Brown algae) AU - Adem Güner Y1 - 2020 PY - 2020 N1 - doi: 10.3153/FH21004 DO - 10.3153/FH21004 T2 - Food and Health JF - Journal JO - JOR SP - 31 EP - 38 VL - 7 IS - 1 SN - -2602-2834 M3 - doi: 10.3153/FH21004 UR - Y2 - 2020 ER -
EndNote %0 Food and Health In vitro risk assessment of Padina pavonica (Linnaeus) (Brown algae) %A Adem Güner %T In vitro risk assessment of Padina pavonica (Linnaeus) (Brown algae) %D 2020 %J Food and Health %P -2602-2834 %V 7 %N 1 %R doi: 10.3153/FH21004 %U 10.3153/FH21004
ISNAD Güner, Adem . "In vitro risk assessment of Padina pavonica (Linnaeus) (Brown algae)". Food and Health 7 / 1 (November 2020): 31-38 .
AMA Güner A . In vitro risk assessment of Padina pavonica (Linnaeus) (Brown algae). Food Health. 2020; 7(1): 31-38.
Vancouver Güner A . In vitro risk assessment of Padina pavonica (Linnaeus) (Brown algae). Food and Health. 2020; 7(1): 31-38.
IEEE A. Güner , "In vitro risk assessment of Padina pavonica (Linnaeus) (Brown algae)", Food and Health, vol. 7, no. 1, pp. 31-38, Nov. 2020, doi:10.3153/FH21004