Apoptosis in cancer

Melisa Beyhan Yılmaz; Dilek Muz

doi:10.47748/tjvr.1121211

Derleme

Apoptosis in cancer

Yıl 2022, Cilt: 6 Sayı: 2, 85 - 95, 25.11.2022

Melisa Beyhan Yılmaz Dilek Muz

https://doi.org/10.47748/tjvr.1121211

Öz

Apoptosis is a programmed cell death mechanism, with its presence and absence, directs the progression of most diseases and is targeted in disease treatments. Many factors are influential in the cell's pathway to apoptosis. The defects in these pathways may transform the cell become malignant, and the organism may face a lethal outcome such as cancer. Understanding apoptosis will provide clues in guiding the pathogenesis of diseases. Two main pathway leading to apoptosis, intrinsic and extrinsic, take an active role. Another route is activated by enzymes and enzymes secreted by immune cells such as T and NK. With their initiator and enforcer roles, many caspase molecules are active at critical points in the cell's apoptosis process. In cancer treatments, activation of molecules in these pathways and repair of disrupted pathways are among the target approaches. This review discuss target strategies for inhibiting apoptotic pathways and molecules in cancer cells and the activation of these apoptotic pathways.

Anahtar Kelimeler

Cell death, Apoptosis, Caspases, Bcl-2 family, Cancer

Destekleyen Kurum

Proje Numarası

Teşekkür

Kaynakça

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Yıl 2022, Cilt: 6 Sayı: 2, 85 - 95, 25.11.2022

Melisa Beyhan Yılmaz Dilek Muz

https://doi.org/10.47748/tjvr.1121211

Öz

Proje Numarası

Kaynakça

Adams J. M, Cory S. The Bcl-2 Arbiters Of Apoptosis And Their Growing Role As Cancer Targets. Cell Death Differ. 2018; 25(1), 27-36.
Akl H, Vervloessem T, Kiviluoto S, et al. A Dual Role For The Anti-Apoptotic Bcl-2 Protein İn Cancer: Mitochondria Versus Endoplasmic Reticulum. Biochimica Et Biophysica Acta(Bba). 2014; 10(1843), 2240-2252.
Berthelet J, Dubrez L. Regulation Of Apoptosis By Inhibitors Of Apoptosis (Iaps). Cells. 2013; 2(1), 163-187.
Blandino G, Agostino S. D. New Therapeutic Strategies To Treat Human Cancers Expressing Mutant P53 Proteins. J Exp Clin Cancer Res. 2018, 15;37(1):30.
Bouillet P, Strasser A. BH3-only proteins — evolutionarily conserved proapoptotic Bcl-2 family members essential for initiating programmed cell death. Journal of Cell Science. 2002; (115), 1567-1574.
Campbell K. J, Tait S. W. G. Targeting Bcl-2 Regulated Apoptosis İn Cancer. Open Biol. 2018; 8(5), 180002. Carrasco R. A, Stamm N. B, Marcusson E, et al. Antisense inhibition of survivin expression as a cancer therapeutic. Mol Cancer Ther. 2011; 10(2), 221-232.
Chen Z, Chen J, Liu H, et al. The SMAC Mimetic APG-1387 Sensitizes Immune-Mediated Cell Apoptosis in Hepatocellular Carcinoma. Frontiers in pharmacology, 2018; 9, 1298.
Clemente N, Boggio E, Gigliotti C. L, et al. A Mutation İn Caspase-9 Decreases The Expression Of Baffr And Icos İn Patients With İmmunodeficiency And Lymphoproliferation. Genes & Immunity. 2015; (16), 151–161.
Cossu F, Milani M, Mastrangelo E, Lecis D. Targeting The BIR Domains Of Inhibitor Of Apoptosis (IAP) Proteins İn Cancer Treatment. Comput Struct Biotechnol J. 2019; (17),142-150.
Dagbay K. B, Hill, M. E, Barrett E, Hardy J. A. Tumor-Associated Mutations in Caspase-6 Negatively Impact Catalytic Efficiency. Biochemistry. 2017; 29; 56(34), 4568–4577.
Dai X, Zhang J, Arfuso F, et al. Targeting TNF-related apoptosis-inducing ligand (TRAIL) receptor by natural products as a potential therapeutic approach for cancer therapy. Exp Biol Med (Maywood). 2015; 240(6),760-773.
Danial N. N, Hockenbery D. M. Chapter 18-Cell death. In Hematology, 7th ed.; Hoffman, R., Benz, E.J., Silberstein, L.E., Heslop, H.E., Weitz, J.I., Anastasi, J., Salama, M.E., Abutalib, S.A., Eds.; Elsevier: Amsterdam, The Netherlands, 2018; 186-196.
Donnelly O. G, Errington-Mais F, Steele L, et al. Measles virus causes immunogenic cell death in human melanoma. Gene Ther. 2013; 20(1),7-15.
Elkholi, R., Floros, K. V., Chipuk, J. E. The role of bh3-only proteins in tumor cell development, signaling and treatment. Genes Cancer. 2011; 2(5),523–537.
Elliott M. R, Chekeni F. B, Trampont P. C, et al. Nucleotides Released by Apoptotic Cells Act as a Find-Me Signal to Promote Phagocytic Clearance. Nature. 2009; 461(7261), 282-286. https://dx.doi.org/10.1038/nature08296.
Elmore S. Apoptosis: A Review Of Programmed Cell Death. Toxicol Pathol. 2007; 35(4), 495-516.
Enari M, Sakahira H, Yokoyama H, Okawa K, Iwamatsu A, Nagata S. A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature. 1998; 391(6662), 43-50.
Falschlehner C, Schaefer U, Walczak H. Following Traıl's Path in The Immune System. Immunology. 2009; 127 (2), 145-154.
Fleming J. B, Shen G. L, Holloway S. E, Davis M, Brekken R. A. Molecular consequences of silencing mutant K-ras in pancreatic cancer cells: Justification for K-ras-directed therapy. Mol Cancer Res. 2005; 3, 413-423.
Fulda, S., Debatin, K. M. Caspase Activation in Cancer Therapy. In: Madame Curie Bioscience Database [Internet]. Austin (TX): Landes Bioscience. 2000-2013.
Fulda S, Debatin K. M. Extrinsic Versus İntrinsic Apoptosis Pathways İn Anticancer Chemotherapy. Oncogene. 2006; (25), 4798-4811.
Garg H, Suri P, Gupta J. C, Talwar G. P, Dubey S. Survivin: a unique target for tumor therapy. Cancer Cell Int. 2016; 23;16:49.
Giorgio M, Migliaccio E, Orsini F, et al. Electron Transfer Between Cytochrome C And P66shc Generates Reactive Oxygen Species That Trigger Mitochondrial Apoptosis. Cell. 2005; 122(2), 221-33.
Green D. R, Llambi F. Cell Death Signaling. Cold Spring Harb Perspect Biol. 2015; 12(3), A006080.
Hensley P, Mishra M, Kyprianou N. Targeting Caspases İn Cancer Therapeutics. Biol Chem. 2013; 394(7), 831-843. https://dx.doi.org/10.1515/hsz-2013-0128.
Humphreys L, Espona‐Fiedler M, Longley D. B. Flıp As A Therapeutic Target İn Cancer. Febs J. 2018; 285(22), 4104-4123.
Hyer M. L, Samuel T, Reed J. C. The Flıp-Side Of Fas Signaling Clinical Cancer Research. 2006; 15(12),5929-31. https://dx.doi.org/10.1158/1078-0432.CCR-06-2098.
Ivanov, V. N., Bhoumik, A., Ronai, Z. Death Receptors And Melanoma Resistance To Apoptosis. Oncogene. 2003; (22), 3152-3161.
Jan R, Chaudhry G. Understanding Apoptosis And Apoptotic Pathways Targeted Cancer Therapeutics. Adv Pharma Bull. 2019; 9(2), 205-218.
Jia L. T, Chen S. Y, Yang A. G. Cancer gene therapy targeting cellular apoptosis machinery. Cancer Treat Rev. 2012; 38, 868-876.
Johnstone R. W, Ruefli A. A, Lowe S. W. Apoptosis: A Link Between Cancer Genetics And Chemotherapy. Article History. 2002; 2(108), 153-164.
Kannan K, Jain S. Oxidative Stress And Apoptosis. Pathophysiology. 2000; 7(3), 153-163.
Karstedt S. V, Montinare A, Walczak H. Exploring the TRAILs less travelled: TRAIL in cancer biology and therapy. Nature Reviews Cancer. 2017; 17, 352-366.
Kerr J. F, Winterford C, Harmon B. Apoptosis. its Significance in Cancer and Cancer Therapy. Cancer. 1994; 15;73(8), 2013-2026.
Kerr J. F, Wyllie A. H, Currie A. R. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer. 1972; 26, 239-257.
Kim J. S, Lee J. H, Jeong W. W. et al. Reactive oxygen species-dependent EndoG release mediates cisplatin-induced caspase-independent apoptosis in human head and neck squamous carcinoma cells. Int J Cancer. 2008 Feb 2008; 1;122(3), 672-80
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Toplam 101 adet kaynakça vardır.

Ayrıntılar

Birincil Dil	İngilizce
Konular	Veteriner Cerrahi
Bölüm	2022 Volume 6 Number 2
Yazarlar	Melisa Beyhan Yılmaz 0000-0002-0769-8742 Dilek Muz 0000-0001-9358-8103
Proje Numarası	-
Erken Görünüm Tarihi	21 Kasım 2022
Yayımlanma Tarihi	25 Kasım 2022
Gönderilme Tarihi	25 Mayıs 2022
Yayımlandığı Sayı	Yıl 2022 Cilt: 6 Sayı: 2

Kaynak Göster

APA	Beyhan Yılmaz, M., & Muz, D. (2022). Apoptosis in cancer. Turkish Journal of Veterinary Research, 6(2), 85-95. https://doi.org/10.47748/tjvr.1121211
AMA	Beyhan Yılmaz M, Muz D. Apoptosis in cancer. TJVR. Kasım 2022;6(2):85-95. doi:10.47748/tjvr.1121211
Chicago	Beyhan Yılmaz, Melisa, ve Dilek Muz. “Apoptosis in Cancer”. Turkish Journal of Veterinary Research 6, sy. 2 (Kasım 2022): 85-95. https://doi.org/10.47748/tjvr.1121211.
EndNote	Beyhan Yılmaz M, Muz D (01 Kasım 2022) Apoptosis in cancer. Turkish Journal of Veterinary Research 6 2 85–95.
IEEE	M. Beyhan Yılmaz ve D. Muz, “Apoptosis in cancer”, TJVR, c. 6, sy. 2, ss. 85–95, 2022, doi: 10.47748/tjvr.1121211.
ISNAD	Beyhan Yılmaz, Melisa - Muz, Dilek. “Apoptosis in Cancer”. Turkish Journal of Veterinary Research 6/2 (Kasım 2022), 85-95. https://doi.org/10.47748/tjvr.1121211.
JAMA	Beyhan Yılmaz M, Muz D. Apoptosis in cancer. TJVR. 2022;6:85–95.
MLA	Beyhan Yılmaz, Melisa ve Dilek Muz. “Apoptosis in Cancer”. Turkish Journal of Veterinary Research, c. 6, sy. 2, 2022, ss. 85-95, doi:10.47748/tjvr.1121211.
Vancouver	Beyhan Yılmaz M, Muz D. Apoptosis in cancer. TJVR. 2022;6(2):85-9.

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