Acute lymphoblastic leukemia (ALL) is an aggressive hematologic malignancy of lymphoid progenitor cells. During treatment of ALL, the patients may be complicated by fatal infections such as sinonasal mucormycosis. In patients with immunocompromised conditions like haematologic malignancies, mucormycosis can be deadly. Once mucormycosis has been detected, it is critical to act quickly to begin treatment. Amphotericin B, posaconazole, or isavuconazole are the medications of choice. Effective treatment requires a long-term course of therapy. Switching to other effective medications should be considered when the preferred treatment is not working. The factors contributing to mucormycosis must also be treated, such as the underlying conditions (haematologic malignancies). Herein, we aimed to discuss a clinically stable ALL patient complicated with extensive sinonasal mucormycosis. She improved with amphotericin B (5 mg/kg/day) and oral posaconazol (300 mg/day) treatment.
acute lymphoblastic leukemia mucormycosis sinonasal mucormycosis Amphoteracin B posaconazol
Birincil Dil | İngilizce |
---|---|
Konular | Kardiyovasküler Tıp ve Hematoloji (Diğer) |
Bölüm | Case Reports |
Yazarlar | |
Yayımlanma Tarihi | 29 Ocak 2024 |
Gönderilme Tarihi | 19 Haziran 2023 |
Kabul Tarihi | 9 Kasım 2023 |
Yayımlandığı Sayı | Yıl 2024 Cilt: 6 Sayı: 1 |