Abstract
Aim: This study investigated the effect of mycophenolate mofetil (MPA) treatment instead of azathioprine (AZA) on renal function after kidney transplantation.
Methods: Thirteen of all recipients were taking a cyclosporine-based regimen and serum creatinine levels were above 1.5 mg/dL. In 13 patients, MPA treatment was started instead of AZA. Renal functions were evaluated for 12 months after MPA treatment.
Results: Serum creatinine levels increased from 2.11±0.48 mg/dL to 2.16±0.72 mg/dL at 12th months. This increase was not statistically significant. Serum creatinine levels decreased in 5 of 13 patients.
Conclusion: In selected patients, conversion from AZA to MPA may slow down the rate of deterioration in graft functions.
azathioprine mycophenolate mofetil kidney transplantation recipient
ULUDAG UNIVERSITY
Birincil Dil | İngilizce |
---|---|
Bölüm | Original Articles |
Yazarlar | |
Yayımlanma Tarihi | 29 Ekim 2019 |
Gönderilme Tarihi | 11 Ekim 2019 |
Kabul Tarihi | 22 Ekim 2019 |
Yayımlandığı Sayı | Yıl 2019 Cilt: 1 Sayı: 1 |