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İmmünoterapi Gören Akciğer Kanserli Hastalarda Diyet Danışmanlığının Rolü

Yıl 2024, Cilt: 15 Sayı: 1, 165 - 173, 22.04.2024

Dilek Doğan Suphiye Mine Yurttagül

https://doi.org/10.22312/sdusbed.1419701

Öz

Akciğer kanseri ağırlıklı olarak 65 ila 84 yaş arası yaşlı bireylerde görülen ve tanı anında ortalama yaş 70 olan, ileri evrede tanı konulabilen, dünya çapında kansere bağlı ölümlerin önde gelen nedeni olarak gösterilen hastalıktır. Akciğer kanserine bağlı 2018 yılında yaklaşık 1,7 milyon birey hayatını kaybetmişken bu oranın küresel olarak 2035 yılına kadar artabileceği ve 3 milyon bireyin hastalığa bağlı olarak hayatını kaybedebileceği tahmin edilmektedir. Türkiye’de erkeklerde akciğer kanseri görülme sıklığı olarak ilk sırada, kadınlarda ise 5.sırada yer almaktadır. Uluslararası rehber görüşlerinde, akciğer kanserinin tedavi yöntemleri olarak kemoterapi, radyoterapi, kemo/radyoterapi, rezeksiyon yer almaktadır. 2018 Nobel Tıp ve Fizyoloji Ödülü ile akciğer kanserli hastalarda devrim niteliğinde kanser immünoterapisi tedavisi literatüre dahil edilmiştir. Kanser immünoterapötik ilaçları, kanser hastalarının tedavisinde büyük başarı gösterse de akciğer kanserli hastalarda malnütrisyon prevalansı %34,5 ile %69 arasında değişmekte olup yüksektir. Kanserli bireylerde malnütrisyon durumunun erken tanınması, bireysel beslenme değerlendirmesinin yapılması hastalığın klinik seyrini ve hastaların yaşam kalitesini olumlu yönde etkileyebilmektedir. İmmünoterapi öncesi ve sonrasında hastanın beslenme durumunu etkileyecek semptomları yönetecek ve diyetisyen tarafından yapılacak, nütrisyonel değerlendirme, nütrisyonel teşhis ve tanı, nütrisyonel müdahale, izleme/değerlendirme süreçlerini içeren diyet danışmanlığı temel tedavi yöntemlerinden biridir. Hasta tedavi sürecinde beslenme durumunu olumsuz etkileyecek hangi yan etkilere (iştahsızlık, tat, koku değişimleri, bulantı, diyare) sahipse, yan etkileri azaltacak ya da düzeltecek ve hastanın tüketebileceği, hastanın sevdiği, hastanın gereksinimi olan makro ve mikro besin öğelerini de karşılayacak beslenme önerilerinde bulunulmalıdır. Nitekim çalışmalar yetersiz beslenme ile immünoterapinin toleransı veya etkinliği arasında bir ilişki olduğunu göstermektedir. Akciğer kanserli hastaların beslenme durumu sürekli değişmektedir ve beslenme müdahale yaklaşımlarının, tedavi semptom yönetiminin zamanında yapılması gerekmektedir.

Anahtar Kelimeler

Akciğer kanseri İmmünoterapi Diyet Danışmanlığı Malnütrisyon

Etik Beyan

Bu çalışma için etik kurul onayına gerek yoktur.

Destekleyen Kurum

Çalışmayı destekleyen kurum veya kuruluş bulunmamaktadır.

Kaynakça

  • [1]Broaddus, V. C. 2021.Murray & Nadel’s Textbook of Respiratory Medicine, Seventh Edition. Elsevier. 2208s
  • [2]T.C. Sağlık Bakanlığı Halk Sağlığı Genel Müdürlüğü Türkiye Kanser İstatistikleri 2018 Verileri. https://hsgm.saglik.gov.tr/depo/birimler/kanser-db/Dokumanlar/Istatistikler/Kanser_Rapor_2018.pdf. (Erişim Tarihi: 15.12.2023).
  • [3]Jemal, A., Bray, F., Center, M. M., Ferlay, J., Ward, E., Forman, D. 2011. Global cancer statistics. CA Cancer J Clin. 61, 69-90.
  • [4]Hecht, S.S. 2012. Lung carcinogenesis by tobacco smoke. Int J Cancer. 131, 2724-2732.
  • [5]Usman Ali, M., Miller, J., Peirson, L., Fitzpatrick-Lewis, D., Kenny, M., Sherifali, D., Raina P. 2016. Screening for Lung Cancer: A Systematic Review and Meta-Analysis. Prev. Med. 89, 301–314.
  • [6]Shankar, A., Dubey A, D. S., al. 2019. Environmental and occupational determinants of lung cancer. Transl Lung Cancer Res. 8, 31-S49.
  • [7]Schabath, M. B., Cote, M. L. 2019. Cancer Progress and Priorities: Lung Cancer. Cancer Epidemiol Biomarkers Prev. 28(10), 1563-1579.
  • [8]Alexander, M., Kim, S. Y., Cheng, H. 2020. Management of Non-Small Cell Lung Cancer. Lung. 198(6), 897-907.
  • [9]Lahiri, A., Maji, A., Potdar, P. D., Singh, N., Parikh, P., Bisht, B., Mukherjee, A., Paul, M. K. 2023. Lung cancer immunotherapy: progress, pitfalls, and promises. Mol Cancer. 21, 22(1), 40.
  • [10]Smyth, M. J., Teng, M. W. 2018 Nobel Prize in physiology or medicine. Clin Transl Immunology. 24, 7(10), 1041.
  • [11]Nigro, E., Perrotta, F., Scialò, F., D’Agnano, V., Mallardo, M., Bianco, A., Daniele, A. 2021. Food, Nutrition, Physical Activity and Microbiota: Which Impact on Lung Cancer? Int J Environ Res Public Health. 1;18(5), 2399.
  • [12]Soeters, P. B., Reijven, P. L., van Bokhorst-de van der Schueren, M. A., Schols, J. M., Halfens, R. J., Meijers, J. M., van Gemert, W. G. 2008. A rational approach to nutritional assessment. Clin Nutr. 27(5), 706-16.
  • [13]Polański, J., Jankowska-Polańska, B., Mazur, G. 2021. Relationship Between Nutritional Status and Quality of Life in Patients with Lung Cancer. Cancer Manag Res. 12(13), 1407-1416.
  • [14]Boloker, G., Wang, C., Zhang, J. 2018. Updated statistics of lung and bronchus cancer in United States. J Thorac Dis. 10(3), 1158-1161.
  • [15]Siegel, R. L., Miller, K. D., Jemal, A. 2018. Cancer statistics. CA Cancer J Clin. 68(1), 7–30.
  • [16]Lehto, R. H. 2016. Symptom burden in lung cancer: management updates. Lung Cancer Manag. 5(2), 61-78.
  • [17]Cederholm, T., Jensen, G. L., Correia, M., Gonzalez, M. C., Fukushima, R., Higashiguchi, T. 2019. GLIM criteria for the diagnosis of malnutrition—a consensus report from the global clinical nutrition community. Clin Nutr. 38(1), 1-9.
  • [18]Phillips, I., Allan, L., Hug, A., Westran, N., Heinemann, C., Hewish, M. 2023. Nutritional status and symptom burden in advanced non-small cell lung cancer: results of the Dietetic Assessment and Intervention in Lung Cancer (DAIL) trial. BMJ Supportive Palliative Care. 13(e1), e213-e219.
  • [19]Güneş, M., Şimşek, A., Demire, B. 2020. Sarkopenik Yaşlı Bireylerde Dirençli Egzersiz Eğitiminin Etkileri. Süleyman Demirel Üniversitesi Sağlık Bilimleri Dergisi. 11(4), 494-9.
  • [20]Sarlkoğpen,Roch, B., Coffy, A., Jean-Baptiste, S., Palaysi, E., Daures, J. P., Pujol, J. L., Bommart S. 2020. Cachexia-Sarcopenia as a Determinant of Disease Control Rate and Survival in Non-Small Lung Cancer Patients Receiving Immune-Checkpoint Inhibitors. Lung Cancer. 143, 19-26.
  • [21]Buentzel, J., Heinz, J., Bleckmann, A., Bauer, C., Röver, C., Bohnenberger, H. 2019. Sarcopenia as prognostic factor in lung cancer patients: a systematic review and meta-analysis. Anticancer Res. 39(9), 4603-12.
  • [22]Fearon, K., Strasser, F., Anker, S. D., Bosaeus, I., Bruera, E., Fainsinger, RL. 2011. Definition and classification of cancer cachexia: an international consensus. Lancet Oncol. 12(5), 489-95.
  • [23]Muscaritoli, M., Lucia, S., Farcomeni, A., Lorusso, V., Saracino, V., Barone, C., Plastino, F., Gori, S., Magarotto, R., Carteni, G., et al. 2017. Prevalence of malnutrition in patients at first medical oncology visit: The PreMiO study. Oncotarget. 8, 79884-79896.
  • [24]Gouez, M., Delrieu, L., Bouleuc, C., Girard, N., Raynard, B., Marchal, T. 2022. Association between Nutritional Status and Treatment Response and Survival in Patients Treated with Immunotherapy for Lung Cancer: A Retrospective French Study. Cancers (Basel). 15, 14(14), 3439.
  • [25]Degens, J. H. R. J., Dingemans, A. C., Willemsen, A. C. H., Gietema, H. A., Hurkmans, D. P.,2021. Aerts J.G., Hendriks L.E.L., Schols A.M.W.J. The Prognostic Value of Weight and Body Composition Changes in Patients with Non-small-cell Lung Cancer Treated with Nivolumab. J. Cachexia Sarcopenia Muscle. 12, 657-664.
  • [26]Polański, J., Świątoniowska-Lonc, N., Kołaczyńska, S., Chabowski, M. 2023. Diet as a Factor Supporting Lung Cancer Treatment-A Systematic Review. Nutrients. 19, 15(6), 1477.
  • [27]Tanaka, N., Takeda, K., Kawasaki, Y., Yamane K., Teruya, Y., Kodani, M., Igishi T., Yamasaki A. 2018. Early Intensive Nutrition Intervention with Dietary Counseling and Oral Nutrition Supplement Prevents Weight Loss in Patients with Advanced Lung Cancer Receiving Chemotherapy: A Clinical Prospective Study. Yonago Acta Med. 61, 204-212.
  • [28]van der Werf, A., Langius, J. A. E., Beeker, A., ten Tije, A. J., Vulink, A.J., Haringhuizen, A., Berkhof, J., van der Vliet, H. J., Verheul, H. M. W., de van der Schueren, M. A. E. 2020. The Effect of Nutritional Counseling on Muscle Mass and Treatment Outcome in Patients with Metastatic Colorectal Cancer Undergoing Chemotherapy: A Randomized Controlled Trial. Clin. Nutr. 39, 3005-3013.
  • [29]Cereda, E., Cappello, S., Colombo, S., Klersy, C., Imarisio, I., Turri, A., Caraccia, M., Borioli V., Monaco, T., Benazzo, M., et al. 2018. Nutritional Counseling with or without Systematic Use of Oral Nutritional Supplements in Head and Neck Cancer Patients Undergoing Radiotherapy. Radiother Oncol. 126, 81-88.
  • [30]Blackwood, H. A., Hall, C. C., Balstad, T. R., Solheim, T. S., Fallon, M., Haraldsdottir, E., Laird, B. J. A. 2020. Systematic Review Examining Nutrition Support Interventions in Patients with Incurable Cancer. Support. Care Cancer. 28, 1877-1889.
  • [31]Jain, R., Coss, C., Whooley, P., Phelps, M., Owen, D. H. 2020. The Role of Malnutrition and Muscle Wasting in Advanced Lung Cancer. Curr Oncol Rep. 22(6), 54.
  • [32]Schiessel, D. L., Baracos, V. E. 2018. Barriers to Cancer Nutrition Therapy: Excess Catabolism of Muscle and Adipose Tissues Induced by Tumour Products and Chemotherapy. Proc. Nutr. Soc. 77, 394-402.
  • [33]Caccialanza, R., Cotogni, P., Cereda, E., Bossi, P., Aprile, G., Delrio, P., Gnagnarella, P., Mascheroni, A., Monge, T., Corradi, E., Grieco, M., Riso, S., De Lorenzo, F., Traclò, F., Iannelli, E., Beretta, G D., Zanetti, M., Cinieri, S., Zagonel, V., Pedrazzoli, P. 2022. Nutritional Support in Cancer patients: update of the Italian Intersociety Working Group practical recommendations. J Cancer. 13(9), 2705-2716.
  • [34]Mele, M C., Rinninella, E., Cintoni, M., Pulcini, G., Di Donato, A., Grassi, F., Trestini, I., Pozzo, C., Tortora, G., Gasbarrini, A., Bria, E. 2021. Nutritional Support in Lung Cancer Patients: The State of the Art. Clin Lung Cancer. 22(4), e584-e594.
  • [35]Muscaritoli, M., Arends, J., Bachmann, P., Baracos, V., Barthelemy, N., Bertz, H., Bozzetti, F., Hütterer, E., Isenring, E., Kaasa, S., Krznaric, Z., Laird, B., Larsson, M., Laviano, A., Mühlebach, S., Oldervoll, L., Ravasco, P., Solheim, T. S., Strasser, F., de van der Schueren, M., Preiser, J. C, Bischoff, S. C. 2021. ESPEN practical guideline: Clinical Nutrition in cancer. Clin Nutr. 40(5), 2898-2913.
  • [36]Nishioka, N., Naito, T., Notsu, A., Mor,i K., Kodama, H., Miyawaki, E., Miyawaki, T., Mamesaya, N., Kobayashi, H., Omori, S., et al. 2020. Unfavorable Impact of Decreased Muscle Quality on the Efficacy of Immunotherapy for Advanced Non-small Cell Lung Cancer. Cancer Med. 10, 247-256.
  • [37]Arends, J., Bachmann, P., Baracos, V., Barthelemy, N., Bertz, H., Bozzetti, F., Fearon, K., Hütterer, E., Isenring, E., Kaasa, S., et al. 2017. ESPEN Guidelines on Nutrition in Cancer Patients. Clin. Nutr. 36, 11-48.
  • [38]Berardi, R., Caramanti, M., Castagnani, M., Guglielmi, S., Marcucci, F., Savini, A., Morgese, F., Rinaldi, S., Ferrini, C., Tiberi, M., et al. 2015. Hyponatremia is a predictor of hospital length and cost of stay and outcome in cancer patients. Support. Care Cancer. 23, 3095–3101.
  • [39]Piccinini, L., Borella, P., Bargellini, A., Medici, C. I., Zoboli, A. A. 1996. case-control study on selenium, zinc, and copper in plasma and hair of subjects affected by breast and lung cancer. Biol. Trace Element Res. 51, 23-30.
  • [40]Bahat, G., Akmansu, M., Güngör, L., ve ark. 2022. Beslenme destek tedavisinde oral nütrisyonel destek ürünleri kullanımı: KEPAN rehberi. Clin Sci Nutr. 4(1): 1-35.

The Role of Dıetary Counselıng in Lung Cancer Patıents Receıvıng Immunotherapy

Yıl 2024, Cilt: 15 Sayı: 1, 165 - 173, 22.04.2024

Dilek Doğan Suphiye Mine Yurttagül

https://doi.org/10.22312/sdusbed.1419701

Öz

Lung cancer is predominantly seen in elderly people aged 65 to 84 years, with an average age of 70 years at the time of diagnosis, can be diagnosed at an advanced stage, and is the leading cause of cancer-related deaths worldwide. While approximately 1.7 million people lost their lives due to lung cancer in 2018, it is estimated that this rate may increase globally until 2035 and 3 million people may lose their lives due to the disease. In Turkey, lung cancer ranks first in terms of incidence in men and 5th in women. International guidelines include chemotherapy, radiotherapy, chemo/radiotherapy and resection as treatment modalities for lung cancer. With the 2018 Nobel Prize in Medicine and Physiology, revolutionary cancer immunotherapy treatment in patients with lung cancer was included in the literature. Although cancer immunotherapeutic drugs have shown great success in the treatment of cancer patients, the prevalence of malnutrition in patients with lung cancer is high, ranging from 34.5% to 69%. Early recognition of malnutrition in cancer patients and individual nutritional assessment can positively affect the clinical course of the disease and the quality of life of patients. Dietary counseling, which includes nutritional assessment, nutritional diagnosis and diagnosis, nutritional intervention, monitoring/evaluation processes, is one of the basic treatment methods that will manage the symptoms that will affect the nutritional status of the patient before and after immunotherapy. If the patient has any side effects (loss of appetite, taste, odor changes, nausea, diarrhea) that may adversely affect his/her nutritional status during the treatment process, nutritional recommendations should be made to reduce or correct the side effects and to meet the macro and micronutrients that the patient can consume, that the patient likes, and that the patient needs. Indeed, studies show that there is a relationship between malnutrition and tolerance or efficacy of immunotherapy. The nutritional status of patients with lung cancer is constantly changing and nutritional intervention approaches and treatment symptom management should be timely.

Anahtar Kelimeler

lung cancer immunotherapy dieatry counseling malnutrition

Kaynakça

  • [1]Broaddus, V. C. 2021.Murray & Nadel’s Textbook of Respiratory Medicine, Seventh Edition. Elsevier. 2208s
  • [2]T.C. Sağlık Bakanlığı Halk Sağlığı Genel Müdürlüğü Türkiye Kanser İstatistikleri 2018 Verileri. https://hsgm.saglik.gov.tr/depo/birimler/kanser-db/Dokumanlar/Istatistikler/Kanser_Rapor_2018.pdf. (Erişim Tarihi: 15.12.2023).
  • [3]Jemal, A., Bray, F., Center, M. M., Ferlay, J., Ward, E., Forman, D. 2011. Global cancer statistics. CA Cancer J Clin. 61, 69-90.
  • [4]Hecht, S.S. 2012. Lung carcinogenesis by tobacco smoke. Int J Cancer. 131, 2724-2732.
  • [5]Usman Ali, M., Miller, J., Peirson, L., Fitzpatrick-Lewis, D., Kenny, M., Sherifali, D., Raina P. 2016. Screening for Lung Cancer: A Systematic Review and Meta-Analysis. Prev. Med. 89, 301–314.
  • [6]Shankar, A., Dubey A, D. S., al. 2019. Environmental and occupational determinants of lung cancer. Transl Lung Cancer Res. 8, 31-S49.
  • [7]Schabath, M. B., Cote, M. L. 2019. Cancer Progress and Priorities: Lung Cancer. Cancer Epidemiol Biomarkers Prev. 28(10), 1563-1579.
  • [8]Alexander, M., Kim, S. Y., Cheng, H. 2020. Management of Non-Small Cell Lung Cancer. Lung. 198(6), 897-907.
  • [9]Lahiri, A., Maji, A., Potdar, P. D., Singh, N., Parikh, P., Bisht, B., Mukherjee, A., Paul, M. K. 2023. Lung cancer immunotherapy: progress, pitfalls, and promises. Mol Cancer. 21, 22(1), 40.
  • [10]Smyth, M. J., Teng, M. W. 2018 Nobel Prize in physiology or medicine. Clin Transl Immunology. 24, 7(10), 1041.
  • [11]Nigro, E., Perrotta, F., Scialò, F., D’Agnano, V., Mallardo, M., Bianco, A., Daniele, A. 2021. Food, Nutrition, Physical Activity and Microbiota: Which Impact on Lung Cancer? Int J Environ Res Public Health. 1;18(5), 2399.
  • [12]Soeters, P. B., Reijven, P. L., van Bokhorst-de van der Schueren, M. A., Schols, J. M., Halfens, R. J., Meijers, J. M., van Gemert, W. G. 2008. A rational approach to nutritional assessment. Clin Nutr. 27(5), 706-16.
  • [13]Polański, J., Jankowska-Polańska, B., Mazur, G. 2021. Relationship Between Nutritional Status and Quality of Life in Patients with Lung Cancer. Cancer Manag Res. 12(13), 1407-1416.
  • [14]Boloker, G., Wang, C., Zhang, J. 2018. Updated statistics of lung and bronchus cancer in United States. J Thorac Dis. 10(3), 1158-1161.
  • [15]Siegel, R. L., Miller, K. D., Jemal, A. 2018. Cancer statistics. CA Cancer J Clin. 68(1), 7–30.
  • [16]Lehto, R. H. 2016. Symptom burden in lung cancer: management updates. Lung Cancer Manag. 5(2), 61-78.
  • [17]Cederholm, T., Jensen, G. L., Correia, M., Gonzalez, M. C., Fukushima, R., Higashiguchi, T. 2019. GLIM criteria for the diagnosis of malnutrition—a consensus report from the global clinical nutrition community. Clin Nutr. 38(1), 1-9.
  • [18]Phillips, I., Allan, L., Hug, A., Westran, N., Heinemann, C., Hewish, M. 2023. Nutritional status and symptom burden in advanced non-small cell lung cancer: results of the Dietetic Assessment and Intervention in Lung Cancer (DAIL) trial. BMJ Supportive Palliative Care. 13(e1), e213-e219.
  • [19]Güneş, M., Şimşek, A., Demire, B. 2020. Sarkopenik Yaşlı Bireylerde Dirençli Egzersiz Eğitiminin Etkileri. Süleyman Demirel Üniversitesi Sağlık Bilimleri Dergisi. 11(4), 494-9.
  • [20]Sarlkoğpen,Roch, B., Coffy, A., Jean-Baptiste, S., Palaysi, E., Daures, J. P., Pujol, J. L., Bommart S. 2020. Cachexia-Sarcopenia as a Determinant of Disease Control Rate and Survival in Non-Small Lung Cancer Patients Receiving Immune-Checkpoint Inhibitors. Lung Cancer. 143, 19-26.
  • [21]Buentzel, J., Heinz, J., Bleckmann, A., Bauer, C., Röver, C., Bohnenberger, H. 2019. Sarcopenia as prognostic factor in lung cancer patients: a systematic review and meta-analysis. Anticancer Res. 39(9), 4603-12.
  • [22]Fearon, K., Strasser, F., Anker, S. D., Bosaeus, I., Bruera, E., Fainsinger, RL. 2011. Definition and classification of cancer cachexia: an international consensus. Lancet Oncol. 12(5), 489-95.
  • [23]Muscaritoli, M., Lucia, S., Farcomeni, A., Lorusso, V., Saracino, V., Barone, C., Plastino, F., Gori, S., Magarotto, R., Carteni, G., et al. 2017. Prevalence of malnutrition in patients at first medical oncology visit: The PreMiO study. Oncotarget. 8, 79884-79896.
  • [24]Gouez, M., Delrieu, L., Bouleuc, C., Girard, N., Raynard, B., Marchal, T. 2022. Association between Nutritional Status and Treatment Response and Survival in Patients Treated with Immunotherapy for Lung Cancer: A Retrospective French Study. Cancers (Basel). 15, 14(14), 3439.
  • [25]Degens, J. H. R. J., Dingemans, A. C., Willemsen, A. C. H., Gietema, H. A., Hurkmans, D. P.,2021. Aerts J.G., Hendriks L.E.L., Schols A.M.W.J. The Prognostic Value of Weight and Body Composition Changes in Patients with Non-small-cell Lung Cancer Treated with Nivolumab. J. Cachexia Sarcopenia Muscle. 12, 657-664.
  • [26]Polański, J., Świątoniowska-Lonc, N., Kołaczyńska, S., Chabowski, M. 2023. Diet as a Factor Supporting Lung Cancer Treatment-A Systematic Review. Nutrients. 19, 15(6), 1477.
  • [27]Tanaka, N., Takeda, K., Kawasaki, Y., Yamane K., Teruya, Y., Kodani, M., Igishi T., Yamasaki A. 2018. Early Intensive Nutrition Intervention with Dietary Counseling and Oral Nutrition Supplement Prevents Weight Loss in Patients with Advanced Lung Cancer Receiving Chemotherapy: A Clinical Prospective Study. Yonago Acta Med. 61, 204-212.
  • [28]van der Werf, A., Langius, J. A. E., Beeker, A., ten Tije, A. J., Vulink, A.J., Haringhuizen, A., Berkhof, J., van der Vliet, H. J., Verheul, H. M. W., de van der Schueren, M. A. E. 2020. The Effect of Nutritional Counseling on Muscle Mass and Treatment Outcome in Patients with Metastatic Colorectal Cancer Undergoing Chemotherapy: A Randomized Controlled Trial. Clin. Nutr. 39, 3005-3013.
  • [29]Cereda, E., Cappello, S., Colombo, S., Klersy, C., Imarisio, I., Turri, A., Caraccia, M., Borioli V., Monaco, T., Benazzo, M., et al. 2018. Nutritional Counseling with or without Systematic Use of Oral Nutritional Supplements in Head and Neck Cancer Patients Undergoing Radiotherapy. Radiother Oncol. 126, 81-88.
  • [30]Blackwood, H. A., Hall, C. C., Balstad, T. R., Solheim, T. S., Fallon, M., Haraldsdottir, E., Laird, B. J. A. 2020. Systematic Review Examining Nutrition Support Interventions in Patients with Incurable Cancer. Support. Care Cancer. 28, 1877-1889.
  • [31]Jain, R., Coss, C., Whooley, P., Phelps, M., Owen, D. H. 2020. The Role of Malnutrition and Muscle Wasting in Advanced Lung Cancer. Curr Oncol Rep. 22(6), 54.
  • [32]Schiessel, D. L., Baracos, V. E. 2018. Barriers to Cancer Nutrition Therapy: Excess Catabolism of Muscle and Adipose Tissues Induced by Tumour Products and Chemotherapy. Proc. Nutr. Soc. 77, 394-402.
  • [33]Caccialanza, R., Cotogni, P., Cereda, E., Bossi, P., Aprile, G., Delrio, P., Gnagnarella, P., Mascheroni, A., Monge, T., Corradi, E., Grieco, M., Riso, S., De Lorenzo, F., Traclò, F., Iannelli, E., Beretta, G D., Zanetti, M., Cinieri, S., Zagonel, V., Pedrazzoli, P. 2022. Nutritional Support in Cancer patients: update of the Italian Intersociety Working Group practical recommendations. J Cancer. 13(9), 2705-2716.
  • [34]Mele, M C., Rinninella, E., Cintoni, M., Pulcini, G., Di Donato, A., Grassi, F., Trestini, I., Pozzo, C., Tortora, G., Gasbarrini, A., Bria, E. 2021. Nutritional Support in Lung Cancer Patients: The State of the Art. Clin Lung Cancer. 22(4), e584-e594.
  • [35]Muscaritoli, M., Arends, J., Bachmann, P., Baracos, V., Barthelemy, N., Bertz, H., Bozzetti, F., Hütterer, E., Isenring, E., Kaasa, S., Krznaric, Z., Laird, B., Larsson, M., Laviano, A., Mühlebach, S., Oldervoll, L., Ravasco, P., Solheim, T. S., Strasser, F., de van der Schueren, M., Preiser, J. C, Bischoff, S. C. 2021. ESPEN practical guideline: Clinical Nutrition in cancer. Clin Nutr. 40(5), 2898-2913.
  • [36]Nishioka, N., Naito, T., Notsu, A., Mor,i K., Kodama, H., Miyawaki, E., Miyawaki, T., Mamesaya, N., Kobayashi, H., Omori, S., et al. 2020. Unfavorable Impact of Decreased Muscle Quality on the Efficacy of Immunotherapy for Advanced Non-small Cell Lung Cancer. Cancer Med. 10, 247-256.
  • [37]Arends, J., Bachmann, P., Baracos, V., Barthelemy, N., Bertz, H., Bozzetti, F., Fearon, K., Hütterer, E., Isenring, E., Kaasa, S., et al. 2017. ESPEN Guidelines on Nutrition in Cancer Patients. Clin. Nutr. 36, 11-48.
  • [38]Berardi, R., Caramanti, M., Castagnani, M., Guglielmi, S., Marcucci, F., Savini, A., Morgese, F., Rinaldi, S., Ferrini, C., Tiberi, M., et al. 2015. Hyponatremia is a predictor of hospital length and cost of stay and outcome in cancer patients. Support. Care Cancer. 23, 3095–3101.
  • [39]Piccinini, L., Borella, P., Bargellini, A., Medici, C. I., Zoboli, A. A. 1996. case-control study on selenium, zinc, and copper in plasma and hair of subjects affected by breast and lung cancer. Biol. Trace Element Res. 51, 23-30.
  • [40]Bahat, G., Akmansu, M., Güngör, L., ve ark. 2022. Beslenme destek tedavisinde oral nütrisyonel destek ürünleri kullanımı: KEPAN rehberi. Clin Sci Nutr. 4(1): 1-35.
Toplam 40 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Klinik Onkoloji
Bölüm Derlemeler
Yazarlar

Dilek Doğan 0000-0003-1800-4635

Suphiye Mine Yurttagül 0000-0001-5170-0523

Yayımlanma Tarihi 22 Nisan 2024
Gönderilme Tarihi 16 Ocak 2024
Kabul Tarihi 3 Nisan 2024
Yayımlandığı Sayı Yıl 2024 Cilt: 15 Sayı: 1

Kaynak Göster

Vancouver Doğan D, Yurttagül SM. İmmünoterapi Gören Akciğer Kanserli Hastalarda Diyet Danışmanlığının Rolü. Süleyman Demirel Üniversitesi Sağlık Bilimleri Dergisi. 2024;15(1):165-73.
 Kapak Resmi İndir

SDÜ Sağlık Bilimleri Dergisi, makalenin gönderilmesi ve yayınlanması dahil olmak üzere hiçbir aşamada herhangi bir ücret talep etmemektedir. Dergimiz, bilimsel araştırmaları okuyucuya ücretsiz sunmanın bilginin küresel paylaşımını artıracağı ilkesini benimseyerek, içeriğine anında açık erişim sağlamaktadır.