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A Relational Database Design for The Compounds Cytotoxically Active on Breast Cancer Cells

Yıl 2022, Cilt: 5 Sayı: 2, 225 - 232, 31.08.2022
https://doi.org/10.35377/saucis...1153071

Öz

Breast cancer is one of the most important global health problems affecting both developed and developing countries. The identification of anticancer compounds, effective on breast cancer cells, is of key importance in chemoprevention investigations and drug development studies. In the literature, there are numerous compounds that have been analyzed for their cytotoxic effects on breast cancer cells, but there is no database where the researchers who want to design a new study on breast cancer can find these compounds all at once. This paper presents a relational database that stores the data of natural and synthetic compounds cytotoxically active on breast cancer cells. The database contains 381 cytotoxicity results and data of 159 compounds, compiled from selected 80 studies. When all this data in our database was queried, it was found out that quercetin, which is a dietary flavonoid, is the most analyzed compound, and MCF-7 cell line is the most used breast cancer cell line.

Kaynakça

  • [1] WHO, “Newsroom Cancer,” 2022. [Online]. Available: https://www.who.int/news-room/fact-sheets/detail/cancer. [Accessed: 24-June-2022].
  • [2] H. Sung, J. Ferlay, R. L. Siegel, M. Laversanne, I. Soerjomataram, A. Jemal, and F. Bray, “Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries,” CA: A Cancer Journal for Clinicians, vol. 71, no. 3, pp. 209-249, 202.
  • [3] E. F. Codd, “A Relational Model of Data for Large Shared Data Banks,” Communications of the ACM, vol. 13, no. 6, pp. 377-387, 1970
Yıl 2022, Cilt: 5 Sayı: 2, 225 - 232, 31.08.2022
https://doi.org/10.35377/saucis...1153071

Öz

Kaynakça

  • [1] WHO, “Newsroom Cancer,” 2022. [Online]. Available: https://www.who.int/news-room/fact-sheets/detail/cancer. [Accessed: 24-June-2022].
  • [2] H. Sung, J. Ferlay, R. L. Siegel, M. Laversanne, I. Soerjomataram, A. Jemal, and F. Bray, “Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries,” CA: A Cancer Journal for Clinicians, vol. 71, no. 3, pp. 209-249, 202.
  • [3] E. F. Codd, “A Relational Model of Data for Large Shared Data Banks,” Communications of the ACM, vol. 13, no. 6, pp. 377-387, 1970
Toplam 3 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Bilgisayar Yazılımı, Yazılım Mühendisliği (Diğer)
Bölüm Makaleler
Yazarlar

Zeynep Oktay 0000-0003-1395-2265

Çiğdem Erol 0000-0002-5057-7145

Nazlı Arda 0000-0002-1043-5652

Yayımlanma Tarihi 31 Ağustos 2022
Gönderilme Tarihi 2 Ağustos 2022
Kabul Tarihi 5 Ağustos 2022
Yayımlandığı Sayı Yıl 2022Cilt: 5 Sayı: 2

Kaynak Göster

IEEE Z. Oktay, Ç. Erol, ve N. Arda, “A Relational Database Design for The Compounds Cytotoxically Active on Breast Cancer Cells”, SAUCIS, c. 5, sy. 2, ss. 225–232, 2022, doi: 10.35377/saucis...1153071.

    Sakarya University Journal of Computer and Information Sciences in Applied Sciences and Engineering: An interdisciplinary journal of information science