Öz
Aim: We aimed to investigate the morphometric development of the orbit and eyeball in the fetal period.
Material and Methods: The present study was carried out on 136 fetal eyes (86 males, 50 females) obtained from 68 fetuses aged between 15-40 gestational weeks. In this study, the area, height, width, volume, depth, and circumference parameters of the orbit were measured, while the anteroposterior and transverse diameters, weight and volume parameters of the eyeball were measured. Also, the diameter at the place where the optic nerve enters the eyeball was measured.
Results: It was determined that all parameters increased during the trimesters and there was a statistically significant difference between the trimesters in all parameters. There was no statistically significant difference in all parameters in terms of gender. In the comparison of the right and left sides, orbital area (p<0.011), orbital circumference (p<0.048) and orbital width (p<0.048) were higher on the right side. There was no difference between the parties in any of the parameters related to the eyeball (p>0.05). However, the diameter of the optic nerve was higher on the left side (p<0.001).
Conclusion: The data we obtained will be very useful in evaluating the pregnancy follow-up by imaging methods such as ultrasonography or magnetic resonance, in the early diagnosis of malformations or diseases, and in planning the treatment.
Anahtar Kelimeler
Destekleyen Kurum
Suleyman Demirel University Instructional Member Training Coordination Unit
Proje Numarası
OYP05444-DR-13
Kaynakça
- Kacar D, Barut C. The anatomy of the orbita wall and the preseptal region: Basic view. Medical Journal of Islamic World Academy of Sciences. 2011;19:15-20.
- Standring S. Gray’s Anatomy: The Anatomical Basis of Clinical Practice. 40th ed. Edinburgh: Churchill Livingstone/Elsevier; 2008.
- Achiron R, Gottlieb Z, Yaron Y, et al. The development of the fetal eye: in utero ultrasonographic measurements of the vitreous and lens. Prenat Diagn. 1995;15:155-60.
- Goldstein I, Tamir A, Zimmer EZ, et al. Growth of the fetal orbit and lens in normal pregnancies. Ultrasound Obstet Gynecol. 1998;12:175-9.
- Dilmen G, Koktener A, Turhan NO, et al. Growth of the fetal lens and orbit. Int J Gynecol Obstet. 2002;76:267–71.
- Robinson AJ, Blaser S, Toi A, et al. MRI of the fetal eyes: morphologic and biometric assessment for abnormal development with ultrasonographic and clinicopathologic correlation. Pediatr Radiol. 2008;38:971-81.
- Haas A, Weigleiin A, Faschinger C, et al. Fetal development of the human orbit. Graefes Arch Clin Exp Ophthalmol. 1993;231:217-20.
- Tomasik E, Czepita D, Zejmo M, et al. Development of the human eyeball and orbit during the fetal life. Ann Acad Med Stetin. 2005;51:37–40.
- Fitzhugh A, Naveed H, Davagnanam I, et al. Proposed three-dimensional model of the orbit and relevance to orbital fracture repair. Surg Radiol Anat. 2016;38:557-61.
- Ramos GA, Ylagan MV, Romine LE, et al. Diagnostic evaluation of the fetal face using 3-dimensional ultrasound. Ultrasound Quarterly. 2008;24:215-23.
- Denis D, Burguiere O, Burillon C. A biometric study of the eye, orbit, and face in 205 normal human fetuses. Invest Ophthalmol Vis Sci. 1998;39:2232-8.
- Ji Y, Qian Z, Dong Y, et al. Quantitative morphometry of the orbit in Chinese adults based on a three-dimensional reconstruction method. J Anat. 2010; 217:501-6.
- Sukonpan K, Phupong V. A biometric study of the fetal orbit and lens in normal pregnancies. J Clin Ultrasound. 2009;37:69-74.
- Seiji F, Moreira RS, Angelis MA, et al. Orbital asymmetry in development: an anatomical study. Orbit. 2009;28:342-6.
- Pommier S, Adalian P, Gaudart J, et al. Fetal age estimation using orbital measurements: 3D CT-Scan study including the effects of trisomy 21. J Forensic Sci. 2009;54:7-12.
- Paquette LB, Jackson HA, Tavare CJ, et al. In utero eye development documented by fetal MR imaging. Am J Neuroradiol. 2009;30:1787-91.
- Ying X, Li H, Yew DT. Morphometric measurements of fetal and neonatal eyes using MRI and ultrasound. Neuroembryology and Aging. 2008;5:60-2.
- Songur A, Tunahan S, Acar T, et al. The investigation of the course of intracranial of optic nerve and histological analysis. Medical Journal of Kocatepe. 2011;12:114-21.
Öz
Anahtar Kelimeler
Proje Numarası
OYP05444-DR-13
Kaynakça
- Kacar D, Barut C. The anatomy of the orbita wall and the preseptal region: Basic view. Medical Journal of Islamic World Academy of Sciences. 2011;19:15-20.
- Standring S. Gray’s Anatomy: The Anatomical Basis of Clinical Practice. 40th ed. Edinburgh: Churchill Livingstone/Elsevier; 2008.
- Achiron R, Gottlieb Z, Yaron Y, et al. The development of the fetal eye: in utero ultrasonographic measurements of the vitreous and lens. Prenat Diagn. 1995;15:155-60.
- Goldstein I, Tamir A, Zimmer EZ, et al. Growth of the fetal orbit and lens in normal pregnancies. Ultrasound Obstet Gynecol. 1998;12:175-9.
- Dilmen G, Koktener A, Turhan NO, et al. Growth of the fetal lens and orbit. Int J Gynecol Obstet. 2002;76:267–71.
- Robinson AJ, Blaser S, Toi A, et al. MRI of the fetal eyes: morphologic and biometric assessment for abnormal development with ultrasonographic and clinicopathologic correlation. Pediatr Radiol. 2008;38:971-81.
- Haas A, Weigleiin A, Faschinger C, et al. Fetal development of the human orbit. Graefes Arch Clin Exp Ophthalmol. 1993;231:217-20.
- Tomasik E, Czepita D, Zejmo M, et al. Development of the human eyeball and orbit during the fetal life. Ann Acad Med Stetin. 2005;51:37–40.
- Fitzhugh A, Naveed H, Davagnanam I, et al. Proposed three-dimensional model of the orbit and relevance to orbital fracture repair. Surg Radiol Anat. 2016;38:557-61.
- Ramos GA, Ylagan MV, Romine LE, et al. Diagnostic evaluation of the fetal face using 3-dimensional ultrasound. Ultrasound Quarterly. 2008;24:215-23.
- Denis D, Burguiere O, Burillon C. A biometric study of the eye, orbit, and face in 205 normal human fetuses. Invest Ophthalmol Vis Sci. 1998;39:2232-8.
- Ji Y, Qian Z, Dong Y, et al. Quantitative morphometry of the orbit in Chinese adults based on a three-dimensional reconstruction method. J Anat. 2010; 217:501-6.
- Sukonpan K, Phupong V. A biometric study of the fetal orbit and lens in normal pregnancies. J Clin Ultrasound. 2009;37:69-74.
- Seiji F, Moreira RS, Angelis MA, et al. Orbital asymmetry in development: an anatomical study. Orbit. 2009;28:342-6.
- Pommier S, Adalian P, Gaudart J, et al. Fetal age estimation using orbital measurements: 3D CT-Scan study including the effects of trisomy 21. J Forensic Sci. 2009;54:7-12.
- Paquette LB, Jackson HA, Tavare CJ, et al. In utero eye development documented by fetal MR imaging. Am J Neuroradiol. 2009;30:1787-91.
- Ying X, Li H, Yew DT. Morphometric measurements of fetal and neonatal eyes using MRI and ultrasound. Neuroembryology and Aging. 2008;5:60-2.
- Songur A, Tunahan S, Acar T, et al. The investigation of the course of intracranial of optic nerve and histological analysis. Medical Journal of Kocatepe. 2011;12:114-21.
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Konular | Klinik Tıp Bilimleri |
| Bölüm | Özgün Makaleler |
| Yazarlar | |
| Proje Numarası | OYP05444-DR-13 |
| Erken Görünüm Tarihi | 15 Mayıs 2023 |
| Yayımlanma Tarihi | 15 Mayıs 2023 |
| Kabul Tarihi | 7 Mart 2023 |
| Yayımlandığı Sayı | Yıl 2023 Cilt: 5 Sayı: 2 |
Chief Editors
Assoc. Prof. Zülal Öner
Address: İzmir Bakırçay University, Department of Anatomy, İzmir, Turkey
Assoc. Prof. Deniz Şenol
Address: Düzce University, Department of Anatomy, Düzce, Turkey
E-mail: medrecsjournal@gmail.com
Publisher:
Medical Records Association (Tıbbi Kayıtlar Derneği)
Address: Düzce / Türkiye
Publication Support:
Effect Publishing & Agency
Phone: + 90 (553) 610 67 80
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