Six
thiazolyl-pyrazoline derivatives were synthesized starting from
corresponding chalcone compounds for their antioxidant capacity and antiurease inhibitory activities. In addition
to the conventional method, ultrasonic sonication and microwave irradiation
methods which are environmental methods were
used in the synthesis stage. Compound
2-(5-(3-bromophenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)-4-phenyl thiazole (5a) exhibited the most potent antiurease
activity with IC50 of 2,28±0,02, which was comparable to the
positive control.
Thiazole microwave irradiation Ultrasound sonication Biological activity
Prof. Dr. Neslihan Demirbaş, Prof. Dr. Ahmet Demirbaş, Chemist MSc Yakup Şirin
Birincil Dil | İngilizce |
---|---|
Konular | Organik Kimya |
Bölüm | Makaleler |
Yazarlar | |
Yayımlanma Tarihi | 15 Şubat 2020 |
Gönderilme Tarihi | 11 Mayıs 2019 |
Kabul Tarihi | 12 Ekim 2019 |
Yayımlandığı Sayı | Yıl 2020 Cilt: 7 Sayı: 1 |