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GEBELİK VE LAKTASYON DÖNEMİNDE COVID 19 ENFEKSİYONUNA KARŞI AŞILAMA: KISA BİR DEĞERLENDİRME

Yıl 2023, Cilt: 47 Sayı: 3, 1132 - 1140, 20.09.2023

Asım Emre Biçer Aysel Pehlivanlı Arif Tanju Özçelikay

https://doi.org/10.33483/jfpau.1261673

Öz

Amaç: Aşılama, Covid 19 enfeksiyonuna karşı korunmada hayati rol oynamaktadır. Bununla birlikte, gebe ve emziren kadınlar aşının anne adayı, fetüs ve bebek üzerindeki bilinmeyen etkileri nedeniyle aşıların klinik denemelerinin dışında tutulmaktadır. Gebelik ve onu takip eden laktasyon dönemleri, anne ve bebek için pek çok uygulamanın tartışıldığı, kendine has fizyolojik, psikolojik ve patolojik özellikleri olan uzun bir süreçtir. Aşı türlerinin etki mekanizmalarına ilişkin mevcut sınırlı verilere dayanarak, Covid 19 aşılarının hamile kadınlar ve emziren anneler için herhangi bir risk oluşturması muhtemel değildir. Öte yandan, şu anda hamile ve emziren kadınlarda Covid 19 aşılarının güvenliğine ilişkin yeterli veri bulunmamaktadır.
Sonuç ve Tartışma: Hamile ve emziren kadınların aşılar hakkında karar vermesini desteklemek için aşılar hakkında kanıta dayalı ve kişiselleştirilmiş bilgilere ihtiyaç vardır. Tüm gebe ve emziren kadınlara Covid 19 aşılarının yararları ve riskleri hakkında yeterince bilgi verildikten ve onamları alındıktan sonra aşı önerilmelidir. Bu bağlamda bu kısa derleme gebelik ve laktasyon döneminde Covid 19 enfeksiyonuna karşı aşılamanın bilimsel verilere ve literatüre dayalı olarak tartışılması amacıyla yapılmıştır.

Anahtar Kelimeler

Aşılama Covid 19 enfeksiyonu gebelik laktasyon

Kaynakça

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VACCINATION AGAINST COVID 19 INFECTION DURING PREGNANCY AND LACTATION: A BRIEF REVIEW

Yıl 2023, Cilt: 47 Sayı: 3, 1132 - 1140, 20.09.2023

Asım Emre Biçer Aysel Pehlivanlı Arif Tanju Özçelikay

https://doi.org/10.33483/jfpau.1261673

Öz

Objective: Vaccination plays a crucial role in the protection against the Covid 19 infection. However, pregnant and lactating women are excluded from clinical trials of vaccines due to the unknown effects of the vaccine on the expectant mother, fetus, and infant. Pregnancy and the following lactation periods are long processes with unique physiological, psychological, and pathological characteristics, in which many practices are discussed for the mother and the baby. Based on the limited data available on the mechanisms of action of vaccine types, Covid 19 vaccines cannot possibly cause any risk to pregnant women and nursing mothers. On the other hand, there is currently insufficient data on the safety of Covid 19 vaccines in pregnant and lactating women.
Result and Discussion: Evidence-based and personalized information about vaccines is needed to support pregnant and breastfeeding women's decision-making about vaccines. Vaccination should be recommended to all pregnant and lactating women after they have been sufficiently informed about the advantage and risks of Covid 19 vaccines and their consent has been obtained. This brief review was conducted to discuss vaccination against Covid 19 infection during pregnancy and the lactation period based on scientific data and literature.

Anahtar Kelimeler

Covid 19 infection lactation pregnancy vaccination

Kaynakça

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  • 10. Abbas-Hanif, A., Rezai, H., Ahmed, S.F., Ahmed, A. (2022). The impact of COVID-19 on pregnancy and therapeutic drug development. British Journal of Pharmacology, 179(10), 2108-2120. [CrossRef]
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  • 29. Maertens, K., Orije, M.R.P., Van Damme, P., Leuridan, E. (2020). Vaccination during pregnancy: current and possible future recommendations. European Journal of Pediatrics, 179(2), 235-242. [CrossRef]
  • 30. Zaman, K., Roy, E., Arifeen, S.E., Rahman, M., Raqib, R., Wilson, E., Omer, S.B., Shahid, N.S., Breiman, R.F., Steinhoff, M.C. (2008). Effectiveness of maternal influenza immunization in mothers and infants. The New England Journal of Medicine, 359(15), 1555-1564. [CrossRef]
  • 31. Dereli, F., Ağartıoğlu Kundakçı, G., Yıldırım, J.G., Uyanık, G., Yılmaz, M. (2021). Aile sağlığı merkezine başvuran gebelerin bağışıklama durumlarının belirlenmesi. İzmir Katip Çelebi Üniversitesi Sağlık Bilimleri Fakültesi Dergisi, 6(2), 77-83.
  • 32. Sezerol, M.A., Davun, S. (2023). COVID-19 vaccine hesitancy and related factors among unvaccinated pregnant women during the pandemic period in Turkey. Vaccines, 11(1), 132. [CrossRef]
  • 33. Maternal and Fetal Medicine and Perinatalogy Society Türkiye Web site (2021). Retrieved June, 2021, from https://www.tmftp.org/files/sunumlar/23-nisan-2015/aliirfankutlar_pm2015.pdf/. Accessed date: 07. 06.2021.
  • 34. Badell, M.L., Dude, C.M., Rasmussen, S.A., Jamieson, D.J. (2022). Covid-19 vaccination in pregnancy. BMJ (Clinical research ed.), 378, e069741.
  • 35. Luxi, N., Giovanazzi, A., Capuano, A., Crisafulli, S., Cutroneo, P.M., Fantini, M.P., Ferrajolo, C., Moretti, U., Poluzzi, E., Raschi, E., Ravaldi, C., Reno, C., Tuccori, M., Vannacci, A., Zanoni, G., Trifirò, G., Ilmiovaccino COVID19 collaborating group (2021). COVID-19 vaccination in pregnancy, paediatrics, immunocompromised patients and persons with history of allergy or prior SARS-CoV-2 infection: Overview of current recommendations and pre- and post-marketing evidence for vaccine efficacy and safety. Drug Safety, 44(12), 1247-1269.
  • 36. Zambrano, L.D., Ellington, S., Strid, P., Galang, R.R., Oduyebo, T., Tong, V.T., Woodworth, K.R., Nahabedian, J.F., 3rd, Azziz-Baumgartner, E., Gilboa, S.M., Meaney-Delman, D., CDC COVID-19 response pregnancy and infant linked outcomes team (2020). Update: Characteristics of symptomatic women of reproductive age with laboratory-confirmed SARS-CoV-2 infection by pregnancy status-United States. Morbidity and Mortality Weekly Report, 69(44), 1641-1647.
  • 37. United States of America State of North Dakota official Web site 2021. Retrieved January, 2021, from https://www.health.nd.gov/sites/www/files/documents/COVID%20Vaccine%20Page/COVID-19_Vaccine_FAQ_General_Public.pdf/. Accessed date: 05.01.2022.
  • 38. Magnus, M.C., Örtqvist, A.K., Dahlqwist, E., Ljung, R., Skår, F., Oakley, L., Macsali, F., Pasternak, B., Gjessing, H.K., Håberg, S.E., Stephansson, O. (2022). Association of SARS-CoV-2 vaccination during pregnancy with pregnancy outcomes. JAMA, 327(15), 1469-1477. [CrossRef]
  • 39. Duran, S. (2008). Tıpta Uzmanlık Tezi. Ebe ve hemşirelerin anne sütü ve emzirme konusundaki bilgi ve tutumlarının, danışmanlık verdikleri annelerin bebeklerini anne sütü ile besleme davranışlarına etkisi. Aile Hekimliği Anabilim Dalı, Tıp Fakültesi, Trakya Üniversitesi, Edirne, Türkiye.
  • 40. American Academy of Pediatrics. (1997). Breast feding and the use of human milk. Pediatrics, 100, 1035.
  • 41. Muyldermans, J., De Weerdt, L., De Brabandere, L., Maertens, K., Tommelein, E. (2022). The effects of COVID-19 vaccination on lactating women: A systematic review of the literature. Frontiers in Immunology, 13, 852928. [CrossRef]
  • 42. Royal College of Obstetricians and Gynaecologists Web site (2021). Retrieved July, 2021, from https://www.rcog.org.uk/en/guidelines-research-services/coronavirus-covid-19-pregnancy-and-womens-health/covid-19-vaccines-and-pregnancy/covid-19-vaccines-pregnancy-and-breastfeeding/. Accessed date: 29.06.2021.
  • 43. Goverment of UK Web site (2021). Retrieved June, 2021, from https://www.gov.uk/government/ publications/covid-19-vaccination-women-of-childbearing-age-currently-pregnant-planning-a-pregnancy-or-breastfeeding/covid-19-vaccination-a-guide-for-women-of-childbearing-age-pregnant-planning-apregn ancy-or-breastfeeding/. Accessed date: 29.06.2021.
  • 44. Moderna Web site (2020). Retrieved November, 2020, from https://investors.modernatx.com/news/news-details/2020/Moderna-Announces-Primary-Efficacy-Analysis-in-Phase-3-COVE-Study-for-Its-COVID-19-Vaccine-Candidate-and-Filing-Today-with-U.S.-FDA-for-Emergency-UseAuthorization/default.aspx/. Accessed date: 07.02.2021.
  • 45. Clinical Trials Web site (2022). Retrieved January, 2022, from https://clinicaltrials.gov/ct2/show /NCT04754594/. Accessed date: 05.01.2022.
  • 46. Republic of Türkiye Ministry of Health Web site (2021). Retrieved July, 2021, from https://covid19asi.saglik.gov.tr/TR-78082/inaktif-covid-19-asisi-gebelere-uygulanabilir-mi.html#:~:text= Gebelikte%20inaktif%20COVID%2D19%20a%C5%9F%C4%B1s%C4%B1n%C4%B1n,kendi%20istekleri%20halinde%20a%C5%9F%C4%B1%20uygulanabilir/. Accessed date: 29.06.2021.
  • 47. Goverment of UK Web site (2021). Retrieved June, 2021, from https://www.gov.uk/government/ publications/safety-of-covid-19-vaccines-when-given-in-pregnancy/the-safety-of-covid-19-vaccines-whe n-given-in-pregnancy/. Accessed date: 29.06.2021.
Toplam 47 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Eczacılık ve İlaç Bilimleri
Bölüm Derleme
Yazarlar

Asım Emre Biçer 0000-0003-1985-4455

Aysel Pehlivanlı 0000-0003-3276-0162

Arif Tanju Özçelikay 0000-0001-9142-9061

Erken Görünüm Tarihi 6 Ağustos 2023
Yayımlanma Tarihi 20 Eylül 2023
Gönderilme Tarihi 12 Mart 2023
Kabul Tarihi 10 Temmuz 2023
Yayımlandığı Sayı Yıl 2023 Cilt: 47 Sayı: 3

Kaynak Göster

APA Biçer, A. E., Pehlivanlı, A., & Özçelikay, A. T. (2023). VACCINATION AGAINST COVID 19 INFECTION DURING PREGNANCY AND LACTATION: A BRIEF REVIEW. Journal of Faculty of Pharmacy of Ankara University, 47(3), 1132-1140. https://doi.org/10.33483/jfpau.1261673
AMA Biçer AE, Pehlivanlı A, Özçelikay AT. VACCINATION AGAINST COVID 19 INFECTION DURING PREGNANCY AND LACTATION: A BRIEF REVIEW. Ankara Ecz. Fak. Derg. Eylül 2023;47(3):1132-1140. doi:10.33483/jfpau.1261673
Chicago Biçer, Asım Emre, Aysel Pehlivanlı, ve Arif Tanju Özçelikay. “VACCINATION AGAINST COVID 19 INFECTION DURING PREGNANCY AND LACTATION: A BRIEF REVIEW”. Journal of Faculty of Pharmacy of Ankara University 47, sy. 3 (Eylül 2023): 1132-40. https://doi.org/10.33483/jfpau.1261673.
EndNote Biçer AE, Pehlivanlı A, Özçelikay AT (01 Eylül 2023) VACCINATION AGAINST COVID 19 INFECTION DURING PREGNANCY AND LACTATION: A BRIEF REVIEW. Journal of Faculty of Pharmacy of Ankara University 47 3 1132–1140.
IEEE A. E. Biçer, A. Pehlivanlı, ve A. T. Özçelikay, “VACCINATION AGAINST COVID 19 INFECTION DURING PREGNANCY AND LACTATION: A BRIEF REVIEW”, Ankara Ecz. Fak. Derg., c. 47, sy. 3, ss. 1132–1140, 2023, doi: 10.33483/jfpau.1261673.
ISNAD Biçer, Asım Emre vd. “VACCINATION AGAINST COVID 19 INFECTION DURING PREGNANCY AND LACTATION: A BRIEF REVIEW”. Journal of Faculty of Pharmacy of Ankara University 47/3 (Eylül 2023), 1132-1140. https://doi.org/10.33483/jfpau.1261673.
JAMA Biçer AE, Pehlivanlı A, Özçelikay AT. VACCINATION AGAINST COVID 19 INFECTION DURING PREGNANCY AND LACTATION: A BRIEF REVIEW. Ankara Ecz. Fak. Derg. 2023;47:1132–1140.
MLA Biçer, Asım Emre vd. “VACCINATION AGAINST COVID 19 INFECTION DURING PREGNANCY AND LACTATION: A BRIEF REVIEW”. Journal of Faculty of Pharmacy of Ankara University, c. 47, sy. 3, 2023, ss. 1132-40, doi:10.33483/jfpau.1261673.
Vancouver Biçer AE, Pehlivanlı A, Özçelikay AT. VACCINATION AGAINST COVID 19 INFECTION DURING PREGNANCY AND LACTATION: A BRIEF REVIEW. Ankara Ecz. Fak. Derg. 2023;47(3):1132-40.
 Kapak Resmi İndir

Kapsam ve Amaç

Ankara Üniversitesi Eczacılık Fakültesi Dergisi, açık erişim, hakemli bir dergi olup Türkçe veya İngilizce olarak farmasötik bilimler alanındaki önemli gelişmeleri içeren orijinal araştırmalar, derlemeler ve kısa bildiriler için uluslararası bir yayım ortamıdır. Bilimsel toplantılarda sunulan bildiriler supleman özel sayısı olarak dergide yayımlanabilir. Ayrıca, tüm farmasötik alandaki gelecek ve önceki ulusal ve uluslararası bilimsel toplantılar ile sosyal aktiviteleri içerir.