Araştırma Makalesi
BibTex RIS Kaynak Göster

In Vitro Anti-Helicobacter Pylori and Antimycobacterial Activity Evaluation Of Selected Plants From Turkey

Yıl 2020, Cilt: 5 Sayı: 2, 231 - 235, 30.06.2020
https://doi.org/10.35229/jaes.689341

Öz

In this study, the extracts of Ulmus minor Mill. subsp. minor (Ulmaceae), Lathyrus pratensis L. (Leguminosae), Glaucium leiocarpum Bois. (Papaveraceae), and Echium vulgare L. (Boraginacea) were investigated for their in vitro anti-Helicobacter pylori and anti-mycobacterial activity.
The air-dried plant material was powdered and extracted with 70% ethanol by maceration. The extract was filtered and evaporated to dryness under the vacuum and then dissolved in a water-ethanol (90:10) mixture and extracted with dichloromethane and ethyl acetate, respectively. Antibacterial activity was investigated by microdilution method against Helicobacter pylori ATCC 43504, Mycobacterium smegmatis ATCC 14468 and Mycobacterium avium ATCC 25291.
The ethyl acetate extract of U. minor showed activity with MIC of 250 µg / mL against H. pylori. The other extracts showed no or weak inhibitory activity at >2000 µg/mL concentrations against the tested microorganisms. In conclusion, ethyl acetate extract of U. minor may be used for the treatment of H. pylori infections.

Kaynakça

  • Arabi, Z., & Sardari, S. (2010). An investigation into the antifungal property of Fabaceae using bioinformatics tools. Avicenna journal of medical biotechnology, 2(2), 93.
  • Baytop T. (1984). Therapy with medicinal plants in Turkey (Past and Present), (p.189) Publication no 325, Istanbul University, Istanbul.
  • Bournine, L., Bensalem, S., Wauters, J. N., Iguer-Ouada, M., Maiza-Benabdesselam, F., Bedjou, F., ... & Frédérich, M. (2013). Identification and quantification of the main active anticancer alkaloids from the root of Glaucium flavum. International journal of molecular sciences, 14(12), 23533-23544.
  • Bulut, G., Haznedaroğlu, M. Z., Doğan, A., Koyu, H., & Tuzlacı, E. (2017). An ethnobotanical study of medicinal plants in Acipayam (Denizli-Turkey). Journal of Herbal Medicine, 10, 64-81.
  • Choi, S. Y., Lee, S., Choi, W. H., Lee, Y., Jo, Y. O., & Ha, T. Y. (2010). Isolation and anti-inflammatory activity of Bakuchiol from Ulmus davidiana var. japonica. Journal of medicinal food, 13(4), 1019-1023.
  • Cullen, J. (1965) Glaucium Mill. in: Davis P.H. (Ed.) Flora of Turkey and the East Aegean islands, Vol 1. Edinburgh University Press, Edinburgh, pp. 214–217.
  • Davis PH. (1982). Flora of Turkey and East Aegean Islands, University Press, Edinburgh.
  • Eşen, B. (2008). Aydınlar Köyü ve çevresinin (Erdemli/Mersin) etnobotanik özellikleri, (p.110), (Doctoral dissertation, Selçuk Üniversitesi Fen Bilimleri Enstitüsü).
  • Hakemi-Vala, M., Mehrara, M., Pourramezan, M., Rahimifard, J. A. N., Khoshnood, S., & Heidary, M. (2017). Comparison the Antimicrobial Effects of the Flowering Aerial Parts of Glaucium vitellinum Boiss. and Buhse and Gaillonia aucheri Jaub. and Spach. Novelty in Biomedicine, 5, 24-29.
  • Heydari, H., Saltan İşcan, G., Eryılmaz, M., Bahadır Acıkara, Ö., Yılmaz Sarıaltın, S., Tekin, M., & Çoban, T. (2019). Antimicrobial and Anti-Inflammatory Activity of Some Lathyrus L. (Fabaceae) Species Growing in Turkey. Turkish Journal of Pharmaceutical Sciences, 16(2).
  • Klemow, K. M., Clements, D. R., Threadgill, P. F., & Cavers, P. B. (2002). The biology of Canadian weeds. 116. Echium vulgare L. Canadian Journal of Plant Science, 82(1), 235-248.
  • Kuruüzüm-Uz, A., Güvenalp, Z., Ströch, K., Demirezer, L. Ö., & Zeeck, A. (2004). Phytochemical and antimicrobial investigation of Echium vulgare growing in Turkey. Biochemical Systematics and Ecology, 32(9), 833-836.
  • Lee, G. Y., Jang, D. S., Kim, J., Kim, C. S., Kim, Y. S., Kim, J. H., & Kim, J. S. (2008). Flavan-3-ols from Ulmus davidiana var. japonica with inhibitory activity on protein glycation. Planta medica, 74(15), 1800-1802.
  • Manganelli, R. U., Camangi, F., & Tomei, P. E. (2001). Curing animals with plants: traditional usage in Tuscany (Italy). Journal of Ethnopharmacology, 78(2-3), 171-191.
  • Morteza-Semnani, K., Amin, G., Shidfar, M. R., Hadizadeh, H., & Shafiee, A. (2003). Antifungal activity of the methanolic extract and alkaloids of Glaucium oxylobum. Fitoterapia, 74(5), 493-496.
  • Orhan, I., Şener, B., Choudhary, M. I., & Khalid, A. (2004). Acetylcholinesterase and butyrylcholinesterase inhibitory activity of some Turkish medicinal plants. Journal of ethnopharmacology, 91(1), 57-60.
  • Papageorgiou, V. P., Assimopoulou, A. N., Couladouros, E. A., Hepworth, D., & Nicolaou, K. C. (1999). The chemistry and biology of alkannin, shikonin, and related naphthazarin natural products. Angewandte Chemie International Edition, 38(3), 270-301.
  • Parsons, W. T., Parsons, W. T., & Cuthbertson, E. G. (2001). Noxious weeds of Australia. CSIRO publishing.
  • Soureshjan, E. H., & Heidari, M. (2014). In vitro Variation in antibacterial activity plant extracts on Glaucium elegans and Saffron (Crocus sativus L.) Onios. Electronic Journal of Biology, 10, 64-67.
  • Tağ, Ö., Yaşa, I., Polat, E., Özgökçe, F., & Karayıldırım, T. (2011). Anti-microbial activities of leaves and stems of Ulmus minor Miller subsp. minor. Planta Medica, 77(12), PM151.
  • Whitmire, J. M., & Merrell, D. S. (2012). Successful culture techniques for Helicobacter species: general culture techniques for Helicobacter pylori. In Helicobacter Species (pp. 17-27). Humana Press, Totowa, NJ.
  • Wikler, M. A. (2006). Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically: approved standard. CLSI (NCCLS), 26, M7-A7.
  • Yeşilada, E., Sezik, E., Honda, G., Takaishi, Y., Takeda, Y., & Tanaka, T. (1999). Traditional medicine in Turkey IX: Folk medicine in north-west Anatolia. Journal of Ethnopharmacology, 64(3), 195-210.
  • Zheng, M. S., Yang, J. H., Li, Y., Li, X., Chang, H. W., & Son, J. K. (2010). Anti-inflammatory activity of constituents isolated from Ulmus davidiana var. japonica. Biomolecules & Therapeutics, 18(3), 321-328.
  • Zhu, X., Skoneczny, D., Weidenhamer, J. D., Mwendwa, J. M., Weston, P. A., Gurr, G. M., ... & Weston, L. A. (2016). Identification and localization of bioactive naphthoquinones in the roots and rhizosphere of Paterson's curse (Echium plantagineum), a noxious invader. Journal of Experimental Botany, 67(12), 3777-3788.
Yıl 2020, Cilt: 5 Sayı: 2, 231 - 235, 30.06.2020
https://doi.org/10.35229/jaes.689341

Öz

Kaynakça

  • Arabi, Z., & Sardari, S. (2010). An investigation into the antifungal property of Fabaceae using bioinformatics tools. Avicenna journal of medical biotechnology, 2(2), 93.
  • Baytop T. (1984). Therapy with medicinal plants in Turkey (Past and Present), (p.189) Publication no 325, Istanbul University, Istanbul.
  • Bournine, L., Bensalem, S., Wauters, J. N., Iguer-Ouada, M., Maiza-Benabdesselam, F., Bedjou, F., ... & Frédérich, M. (2013). Identification and quantification of the main active anticancer alkaloids from the root of Glaucium flavum. International journal of molecular sciences, 14(12), 23533-23544.
  • Bulut, G., Haznedaroğlu, M. Z., Doğan, A., Koyu, H., & Tuzlacı, E. (2017). An ethnobotanical study of medicinal plants in Acipayam (Denizli-Turkey). Journal of Herbal Medicine, 10, 64-81.
  • Choi, S. Y., Lee, S., Choi, W. H., Lee, Y., Jo, Y. O., & Ha, T. Y. (2010). Isolation and anti-inflammatory activity of Bakuchiol from Ulmus davidiana var. japonica. Journal of medicinal food, 13(4), 1019-1023.
  • Cullen, J. (1965) Glaucium Mill. in: Davis P.H. (Ed.) Flora of Turkey and the East Aegean islands, Vol 1. Edinburgh University Press, Edinburgh, pp. 214–217.
  • Davis PH. (1982). Flora of Turkey and East Aegean Islands, University Press, Edinburgh.
  • Eşen, B. (2008). Aydınlar Köyü ve çevresinin (Erdemli/Mersin) etnobotanik özellikleri, (p.110), (Doctoral dissertation, Selçuk Üniversitesi Fen Bilimleri Enstitüsü).
  • Hakemi-Vala, M., Mehrara, M., Pourramezan, M., Rahimifard, J. A. N., Khoshnood, S., & Heidary, M. (2017). Comparison the Antimicrobial Effects of the Flowering Aerial Parts of Glaucium vitellinum Boiss. and Buhse and Gaillonia aucheri Jaub. and Spach. Novelty in Biomedicine, 5, 24-29.
  • Heydari, H., Saltan İşcan, G., Eryılmaz, M., Bahadır Acıkara, Ö., Yılmaz Sarıaltın, S., Tekin, M., & Çoban, T. (2019). Antimicrobial and Anti-Inflammatory Activity of Some Lathyrus L. (Fabaceae) Species Growing in Turkey. Turkish Journal of Pharmaceutical Sciences, 16(2).
  • Klemow, K. M., Clements, D. R., Threadgill, P. F., & Cavers, P. B. (2002). The biology of Canadian weeds. 116. Echium vulgare L. Canadian Journal of Plant Science, 82(1), 235-248.
  • Kuruüzüm-Uz, A., Güvenalp, Z., Ströch, K., Demirezer, L. Ö., & Zeeck, A. (2004). Phytochemical and antimicrobial investigation of Echium vulgare growing in Turkey. Biochemical Systematics and Ecology, 32(9), 833-836.
  • Lee, G. Y., Jang, D. S., Kim, J., Kim, C. S., Kim, Y. S., Kim, J. H., & Kim, J. S. (2008). Flavan-3-ols from Ulmus davidiana var. japonica with inhibitory activity on protein glycation. Planta medica, 74(15), 1800-1802.
  • Manganelli, R. U., Camangi, F., & Tomei, P. E. (2001). Curing animals with plants: traditional usage in Tuscany (Italy). Journal of Ethnopharmacology, 78(2-3), 171-191.
  • Morteza-Semnani, K., Amin, G., Shidfar, M. R., Hadizadeh, H., & Shafiee, A. (2003). Antifungal activity of the methanolic extract and alkaloids of Glaucium oxylobum. Fitoterapia, 74(5), 493-496.
  • Orhan, I., Şener, B., Choudhary, M. I., & Khalid, A. (2004). Acetylcholinesterase and butyrylcholinesterase inhibitory activity of some Turkish medicinal plants. Journal of ethnopharmacology, 91(1), 57-60.
  • Papageorgiou, V. P., Assimopoulou, A. N., Couladouros, E. A., Hepworth, D., & Nicolaou, K. C. (1999). The chemistry and biology of alkannin, shikonin, and related naphthazarin natural products. Angewandte Chemie International Edition, 38(3), 270-301.
  • Parsons, W. T., Parsons, W. T., & Cuthbertson, E. G. (2001). Noxious weeds of Australia. CSIRO publishing.
  • Soureshjan, E. H., & Heidari, M. (2014). In vitro Variation in antibacterial activity plant extracts on Glaucium elegans and Saffron (Crocus sativus L.) Onios. Electronic Journal of Biology, 10, 64-67.
  • Tağ, Ö., Yaşa, I., Polat, E., Özgökçe, F., & Karayıldırım, T. (2011). Anti-microbial activities of leaves and stems of Ulmus minor Miller subsp. minor. Planta Medica, 77(12), PM151.
  • Whitmire, J. M., & Merrell, D. S. (2012). Successful culture techniques for Helicobacter species: general culture techniques for Helicobacter pylori. In Helicobacter Species (pp. 17-27). Humana Press, Totowa, NJ.
  • Wikler, M. A. (2006). Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically: approved standard. CLSI (NCCLS), 26, M7-A7.
  • Yeşilada, E., Sezik, E., Honda, G., Takaishi, Y., Takeda, Y., & Tanaka, T. (1999). Traditional medicine in Turkey IX: Folk medicine in north-west Anatolia. Journal of Ethnopharmacology, 64(3), 195-210.
  • Zheng, M. S., Yang, J. H., Li, Y., Li, X., Chang, H. W., & Son, J. K. (2010). Anti-inflammatory activity of constituents isolated from Ulmus davidiana var. japonica. Biomolecules & Therapeutics, 18(3), 321-328.
  • Zhu, X., Skoneczny, D., Weidenhamer, J. D., Mwendwa, J. M., Weston, P. A., Gurr, G. M., ... & Weston, L. A. (2016). Identification and localization of bioactive naphthoquinones in the roots and rhizosphere of Paterson's curse (Echium plantagineum), a noxious invader. Journal of Experimental Botany, 67(12), 3777-3788.
Toplam 25 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Bölüm Makaleler
Yazarlar

Ayşe Esra Karadağ 0000-0002-3412-0807

Ayşegül Çaşkurlu Bu kişi benim 0000-0001-7277-920X

Fatma Tosun 0000-0003-2533-5141

Yayımlanma Tarihi 30 Haziran 2020
Gönderilme Tarihi 14 Şubat 2020
Kabul Tarihi 5 Haziran 2020
Yayımlandığı Sayı Yıl 2020 Cilt: 5 Sayı: 2

Kaynak Göster

APA Karadağ, A. E., Çaşkurlu, A., & Tosun, F. (2020). In Vitro Anti-Helicobacter Pylori and Antimycobacterial Activity Evaluation Of Selected Plants From Turkey. Journal of Anatolian Environmental and Animal Sciences, 5(2), 231-235. https://doi.org/10.35229/jaes.689341


13221            13345           13349              13352              13353              13354          13355    13356   13358   13359   13361     13363   13364                crossref1.png            
         Paperity.org                                  13369                                         EBSCOHost                                                        Scilit                                                    CABI   
JAES/AAS-Journal of Anatolian Environmental and Animal Sciences/Anatolian Academic Sciences&Anadolu Çevre ve Hayvancılık Dergisi/Anadolu Akademik Bilimler-AÇEH/AAS