Olgu Sunumu
Yıl 2017,
Cilt: 42 Sayı: 2, 369 - 372, 30.06.2017
Öz
Jarcho-Levin sendromu vertebra deformitelerin olduğu ve sinir sistemi, kardiyak, üriner ve gastrointestinal sistemi ilgilendiren birçok anomalinin de eşlik edebildiği bir sendromdur. İnsidansı 2.5/100.000 olup meningomiyelosel ve hidrosefali bu olguların dörtte birine eşlik eder. Hastalar genellikle solunum yetmezliği ile kaybedilirler. Bu yazıda meningomiyelosel ve hidrosefalisi olan ve opere edilen iki spondilotorasik tip Jarcho-Levin olgusu sunulmuştur.
Anahtar Kelimeler
Kaynakça
- 1. Jarcho S, Levin PM. Hereditary malformation of the vertebral bodies. Johns Hopkins Hosp. 1938;62:216-26. 2. Güzoğlu N, Dilli D, Oğuz SŞ, Kızılelma A, Erdeve Ö, Ceylaner S ve ark. Nöral tüp defektinin eşlik ettiği spondilotorakal tip Jarcho-Levın Sendromu: Bir olgu sunumu. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 2010;63:65-7. 3. Aydın H, Çifçi E, Hekimoğlu B. Jarcho-Levın Sendromu: Spondilokostal Displazili yenidoğanda direkt grafi bulguları. Yeni Tıp Dergisi. 2008;25:245-7. 4. Miscellaneous syndromes. In: Smith’s Recognizable Patterns of Human Malformation. 7th ed (Eds KL Jones, MC Jones, M Casanelles): Philadelphia, Elsevier Saunders. 2013;782-3. 5. Kulkarni ML, Navaz S, Vani HN, Manjunath KS, Matani D. Jarcho Levin Syndrome. Indian J Pediatr. 2006;73:245-7. 6. Gedikbasi A, Yıldırım G, Bingol B, İsmayilzade R, Celikkol O, Ceylan Y. Nöral tüp defekti ve iniensefali ile komplike olmuş Jarcho –Levin Sendromu. JOPP Derg. 2010;2:89-92. 7. Gucev ZS, Tasic V, Pop-Jordanova N, Sparrow DB, Dunwoodie SL, Ellard S et al. Autosomal dominant spondylocostal dysostosis in three generations of a Macedonian family: negative mutation analysis of DLL3, MESP2, HES7 and LFNG. Am J Med Genet. 2010;152:1378-82. 8. Cornier AS, Staehling-Hampton K, Delventhal KM, Saga Y, Caubet JF, Sasaki N et al. Mutations in the MESP2 Gene Cause Spondylothoracic Dysostosis/ Jarcho-Levin Syndrome, Am J Hum Genet. 2008;82:1334–41. 9. Dane B, Dane C, Aksoy F, Cetin A, Yayla M. Jarcho-Levin syndrome presenting as neural tube defect: report of four cases and pitfalls of diagnosis. Fetal Diagn Ther. 2007;22:416-9. 10. Mortier GR, Lachman RS, Bocian M, Rimoin DL. Multiple vertebral segmentation defects: analysis of 26 new patients and review of the literature. Am J Med Genet. 1996;61:310-9. 11. Akın MA, Güneş T, Baykan A, Çoban D, Sezer S, Vatankulu F. Aynı olguda iki nadir hastalık: Jarcho-Levin Sendromuve komplex kardiyak patoloji. Turkish J Pediatr Dis. 2010;4:104-8. 12. Odacı E, Yıldıran A, Küçüködük Ş, Çiftçi N. Abnormalities may be related defective somitogenesis: multiple vertebral segmentation defects and neural tube defects. O.M.Ü. Tıp Dergisi. 2001;18:216-24. 13. Chen CP. Syndromes, Disorders and Maternal Risk Factors Associated With Syndromes, Disorders and Maternal Risk Factors Associated with Neural Tube Defects (II). Taiwan J Obstet Gynecol. 2008;47:10-7. 14. Naik PR, Lendon RG, Barson AJ. A radiological study of vertebral and rib malformations in children with myelomeningocele. Clin Radiol. 1978;29:427-30
Yıl 2017,
Cilt: 42 Sayı: 2, 369 - 372, 30.06.2017
Öz
Jarcho-Levin syndrome is associated with vertebra, central nervous system, cardiac, urinary and gastrointestinal system abnormalities. Incidence is 2.5/100000 and meningomyelocel and hydrocephalus is rare, in about 1/4 of the Jarcho-Levin cases. Patients die due to respiratory insufficiency. Here we present two cases of Jarcho-Levin syndrome operated for meningomyelocele and hydrocephalus.
Anahtar Kelimeler
Kaynakça
- 1. Jarcho S, Levin PM. Hereditary malformation of the vertebral bodies. Johns Hopkins Hosp. 1938;62:216-26. 2. Güzoğlu N, Dilli D, Oğuz SŞ, Kızılelma A, Erdeve Ö, Ceylaner S ve ark. Nöral tüp defektinin eşlik ettiği spondilotorakal tip Jarcho-Levın Sendromu: Bir olgu sunumu. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 2010;63:65-7. 3. Aydın H, Çifçi E, Hekimoğlu B. Jarcho-Levın Sendromu: Spondilokostal Displazili yenidoğanda direkt grafi bulguları. Yeni Tıp Dergisi. 2008;25:245-7. 4. Miscellaneous syndromes. In: Smith’s Recognizable Patterns of Human Malformation. 7th ed (Eds KL Jones, MC Jones, M Casanelles): Philadelphia, Elsevier Saunders. 2013;782-3. 5. Kulkarni ML, Navaz S, Vani HN, Manjunath KS, Matani D. Jarcho Levin Syndrome. Indian J Pediatr. 2006;73:245-7. 6. Gedikbasi A, Yıldırım G, Bingol B, İsmayilzade R, Celikkol O, Ceylan Y. Nöral tüp defekti ve iniensefali ile komplike olmuş Jarcho –Levin Sendromu. JOPP Derg. 2010;2:89-92. 7. Gucev ZS, Tasic V, Pop-Jordanova N, Sparrow DB, Dunwoodie SL, Ellard S et al. Autosomal dominant spondylocostal dysostosis in three generations of a Macedonian family: negative mutation analysis of DLL3, MESP2, HES7 and LFNG. Am J Med Genet. 2010;152:1378-82. 8. Cornier AS, Staehling-Hampton K, Delventhal KM, Saga Y, Caubet JF, Sasaki N et al. Mutations in the MESP2 Gene Cause Spondylothoracic Dysostosis/ Jarcho-Levin Syndrome, Am J Hum Genet. 2008;82:1334–41. 9. Dane B, Dane C, Aksoy F, Cetin A, Yayla M. Jarcho-Levin syndrome presenting as neural tube defect: report of four cases and pitfalls of diagnosis. Fetal Diagn Ther. 2007;22:416-9. 10. Mortier GR, Lachman RS, Bocian M, Rimoin DL. Multiple vertebral segmentation defects: analysis of 26 new patients and review of the literature. Am J Med Genet. 1996;61:310-9. 11. Akın MA, Güneş T, Baykan A, Çoban D, Sezer S, Vatankulu F. Aynı olguda iki nadir hastalık: Jarcho-Levin Sendromuve komplex kardiyak patoloji. Turkish J Pediatr Dis. 2010;4:104-8. 12. Odacı E, Yıldıran A, Küçüködük Ş, Çiftçi N. Abnormalities may be related defective somitogenesis: multiple vertebral segmentation defects and neural tube defects. O.M.Ü. Tıp Dergisi. 2001;18:216-24. 13. Chen CP. Syndromes, Disorders and Maternal Risk Factors Associated With Syndromes, Disorders and Maternal Risk Factors Associated with Neural Tube Defects (II). Taiwan J Obstet Gynecol. 2008;47:10-7. 14. Naik PR, Lendon RG, Barson AJ. A radiological study of vertebral and rib malformations in children with myelomeningocele. Clin Radiol. 1978;29:427-30
Toplam 1 adet kaynakça vardır.
Ayrıntılar
| Konular | Sağlık Kurumları Yönetimi |
|---|---|
| Bölüm | Olgu Sunumu |
| Yazarlar | |
| Yayımlanma Tarihi | 30 Haziran 2017 |
| Kabul Tarihi | 7 Eylül 2016 |
| Yayımlandığı Sayı | Yıl 2017 Cilt: 42 Sayı: 2 |
