Öz
Kaynakça
- Zhu N, Zhang D, Wang W, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med 2020; 382: 727-33.
- COVID C, Team R. Severe outcomes among patients with coronavirus disease 2019 (COVID-19)—United States, February 12–March 16, 2020. MMWR Morb Mortal Wkly Rep 2020; 69: 343-46.
- Xie X, Zhong Z, Zhao W, Zheng C, Wang F, Liu J. Chest CT for typical 2019-nCoV pneumonia: relationship to negative RT-PCR testing. Radiology 2020; 200343.
- Wu WC, Chiou YY, Hung HH, et al. Prognostic significance of computed tomography scan-derived splenic volume in hepato- cellular carcinoma treated with radiofrequency ablation. J Clin Gastroenterol 2012; 46: 789–95.
- Strijk SP, Wagener DJ, Bogman MJ, de Pauw BE, Wobbes T. The spleen in Hodgkin disease: diagnostic value of CT. Radiology 1985; 154: 753–7.
- Konus OL, Ozdemir A, Akkaya A, Erbas G, Celik H, Isik S. Normal liver, spleen, and kidney dimensions in neonates, infants, and children: evaluation with sonography. AJR Am J Roentgenology 1998; 171: 1693-8.
- Loftus WK, Chow LTC, Metreweli C. Sonographic measurement of splenic length: correlation with measurement at autopsy. J Clin Ultrasound 1999; 27: 71–4.
- Sandrasegaran K, Kwo PW, DiGirolamo D, Stockberger SM, Cum- mings OW, Kopecky KK. Measurement of liver volume using spiral CT and the curved line and cubic spline algorithms: reproducibility and interobserver variation. Abdominal Imaging 1999; 24: 61–5.
- Schiano TD, Bodian C, Schwartz ME, Glajchen N, Min AD. Accuracy and significance of computed tomographic scan assessment of hepatic volume in patients undergoing liver transplantation. Transplantation 2000; 69: 545–50.
- Kucybała I, Ciuk S, Tęczar J. Spleen enlargement assessment using computed tomography: which coefficient correlates the strongest with the real volume of the spleen? Abdominal Radiology 2018; 43.9: 2455-61.
- Chen N, Zhou M, Dong X, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. The Lancet 2020; 395: 507-13.
- Fan W, Su Z, Bin Y, et al. Holmes Edward C., Zhang Yong-Zhen. A new coronavirus associated with human respiratory disease in China. Nature 2020; 579: 265-69.
- Xu X, Chang XN, Pan HX, et al. Pathological changes of the spleen in ten patients with coronavirus disease 2019 (COVID-19) by postmortem needle autopsy. Zhonghua bing li xue za zhi= Chinese journal of pathology 2020; 49: 576-82.
- Lamb PM, Lund A, Kanagasabay RR, Martin A, Webb JAW, Reznek RH. Spleen size: how well do linear ultrasound measurements correlate with threedimensional CT volume assessments?. Br J Radiol 2002; 75: 573–7.
- Elstein D, Hadas-Halpern I, Azuri Y, Abrahamov A, Bar-ziv Y, Zimran A. Accuracy of ultrasonography in assessing spleen and liver size in patients with Gaucher disease: comparison to computed tomographic measurements. J Ultrasound Med 1997; 16: 209–11.
- Linguraru MG, Sandberg JK, Jones EC, Summers RM. Assessing splenomegaly: automated volumetric analysis of the spleen. Acad Radiol 2013; 20: 675–84.
- Yetter EM, Acosta KB, Olson MC, Blundell K. Estimating splenic volume: sonographic measurements correlated with helical CT determination. AJR Am J Roentgenology 2003; 181: 1615–20.
- Prassopoulos P, Cavouras D. CT assessment of normal splenic size in children. Acta Radiologica 1994; 35: 152–4.
Öz
Abstract
Objectives There is not enough data on the effect of COVID 19 on spleen volume in patients with COVID-19. Our aim was to compare the spleen volume of the COVID-19 patients with the control group.
Methods 214 Patients (121 men, 93 women) who have a diagnosis of COVID 19 who have thorax CT were included in the study. In the patient group, there was evidence of viral pneumonia on thoracic CT or PCR was positive, all of them were patients who received treatment for COVID. The control group consisted of 185 patients (106 men, 79 women). Interobserver agreement was calculated. Analysis of the receiver operating characteristic (ROC) curve was used to identify a spleen volume cutoff value at which the accuracy for COVID 19 diagnosis was maximised.
Results The mean spleen volume of the patient group was found to be 260 (range, 96.3-565, SD: 82.5) which was statistically significantly higher than the control group which was 220 (range, 125.9-331.9, SD: 34.5) (p <0.05). Excellent agreement was found between two blind observers and between intraobserver spleen volume measurements. In our study, the spleen volume for the diagnosis of COVID-19 pneumonia was 208.4 (AUC 0.639; 95% CI 0.584-0.695), sensitivity and specificity were 69.6% and 66.7%, respectively.
Conclusions Quantitative evaluation of spleen volume can give an idea about the COVID diagnosis. Spleen volume is higher in COVID group than control group.
Anahtar Kelimeler
coronavirus disease COVID-19 computed tomography Splenomegaly
Kaynakça
- Zhu N, Zhang D, Wang W, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med 2020; 382: 727-33.
- COVID C, Team R. Severe outcomes among patients with coronavirus disease 2019 (COVID-19)—United States, February 12–March 16, 2020. MMWR Morb Mortal Wkly Rep 2020; 69: 343-46.
- Xie X, Zhong Z, Zhao W, Zheng C, Wang F, Liu J. Chest CT for typical 2019-nCoV pneumonia: relationship to negative RT-PCR testing. Radiology 2020; 200343.
- Wu WC, Chiou YY, Hung HH, et al. Prognostic significance of computed tomography scan-derived splenic volume in hepato- cellular carcinoma treated with radiofrequency ablation. J Clin Gastroenterol 2012; 46: 789–95.
- Strijk SP, Wagener DJ, Bogman MJ, de Pauw BE, Wobbes T. The spleen in Hodgkin disease: diagnostic value of CT. Radiology 1985; 154: 753–7.
- Konus OL, Ozdemir A, Akkaya A, Erbas G, Celik H, Isik S. Normal liver, spleen, and kidney dimensions in neonates, infants, and children: evaluation with sonography. AJR Am J Roentgenology 1998; 171: 1693-8.
- Loftus WK, Chow LTC, Metreweli C. Sonographic measurement of splenic length: correlation with measurement at autopsy. J Clin Ultrasound 1999; 27: 71–4.
- Sandrasegaran K, Kwo PW, DiGirolamo D, Stockberger SM, Cum- mings OW, Kopecky KK. Measurement of liver volume using spiral CT and the curved line and cubic spline algorithms: reproducibility and interobserver variation. Abdominal Imaging 1999; 24: 61–5.
- Schiano TD, Bodian C, Schwartz ME, Glajchen N, Min AD. Accuracy and significance of computed tomographic scan assessment of hepatic volume in patients undergoing liver transplantation. Transplantation 2000; 69: 545–50.
- Kucybała I, Ciuk S, Tęczar J. Spleen enlargement assessment using computed tomography: which coefficient correlates the strongest with the real volume of the spleen? Abdominal Radiology 2018; 43.9: 2455-61.
- Chen N, Zhou M, Dong X, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. The Lancet 2020; 395: 507-13.
- Fan W, Su Z, Bin Y, et al. Holmes Edward C., Zhang Yong-Zhen. A new coronavirus associated with human respiratory disease in China. Nature 2020; 579: 265-69.
- Xu X, Chang XN, Pan HX, et al. Pathological changes of the spleen in ten patients with coronavirus disease 2019 (COVID-19) by postmortem needle autopsy. Zhonghua bing li xue za zhi= Chinese journal of pathology 2020; 49: 576-82.
- Lamb PM, Lund A, Kanagasabay RR, Martin A, Webb JAW, Reznek RH. Spleen size: how well do linear ultrasound measurements correlate with threedimensional CT volume assessments?. Br J Radiol 2002; 75: 573–7.
- Elstein D, Hadas-Halpern I, Azuri Y, Abrahamov A, Bar-ziv Y, Zimran A. Accuracy of ultrasonography in assessing spleen and liver size in patients with Gaucher disease: comparison to computed tomographic measurements. J Ultrasound Med 1997; 16: 209–11.
- Linguraru MG, Sandberg JK, Jones EC, Summers RM. Assessing splenomegaly: automated volumetric analysis of the spleen. Acad Radiol 2013; 20: 675–84.
- Yetter EM, Acosta KB, Olson MC, Blundell K. Estimating splenic volume: sonographic measurements correlated with helical CT determination. AJR Am J Roentgenology 2003; 181: 1615–20.
- Prassopoulos P, Cavouras D. CT assessment of normal splenic size in children. Acta Radiologica 1994; 35: 152–4.
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Konular | Sağlık Kurumları Yönetimi |
| Bölüm | Research Articles |
| Yazarlar | |
| Yayımlanma Tarihi | 24 Nisan 2021 |
| Yayımlandığı Sayı | Yıl 2021 Cilt: 3 Sayı: 2 |
Üniversitelerarası Kurul (ÜAK) Eşdeğerliği: Ulakbim TR Dizin'de olan dergilerde yayımlanan makale [10 PUAN] ve 1a, b, c hariç uluslararası indekslerde (1d) olan dergilerde yayımlanan makale [5 PUAN]
- Dahil olduğumuz İndeksler (Dizinler) ve Platformlar sayfanın en altındadır.
Not: Dergimiz WOS indeksli değildir ve bu nedenle Q olarak sınıflandırılmamaktadır.
Yüksek Öğretim Kurumu (YÖK) kriterlerine göre yağmacı/şüpheli dergiler hakkındaki kararları ile yazar aydınlatma metni ve dergi ücretlendirme politikasını tarayıcınızdan indirebilirsiniz. https://dergipark.org.tr/tr/journal/3449/page/10809/update
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