Ramazan Ayının ve Mevsimlerin Peptik Ülser Perforasyonları Üzerine Olan Etkilerinin Değerlendirilmesi
Öz
Amaç: Peptik ülser perforasyonu en önemli cerrahi acillerden birisidir. Bu çalışmada ramazan ayının ve mevsimlerin peptik ülser perforasyonları üzerine olan muhtemel etkilerinin değerlendirilmesi amaçlanmıştır.
Gereç ve Yöntemler: Kliniğimizde peptik ülser perforasyonu nedeniyle opere edilen hastalar retrospektif olarak değerlendirildi. Hastalara ait demografik ve klinik veriler, operasyon tarihi, uygulanan ameliyat tekniği ve post-operatif takip verileri kaydedildi. Ayrıca, vakaların ramazan ayında görülme sıklığı ve kliniği de kaydedildi. Elde edilen veriler ile vakaların mevsimsel ve aylık karşılaştırması yapıldı.
Bulgular: Çalışmaya toplam 72 hasta dahil edildi. Hastaların 14 (%19)’ü kadın, 58 (%81)’ i erkek idi. Kadın hastaların yaş ortalaması 64±23, erkek hastaların ise 44±17 idi ( p <0,001). Hastaların 8 (%11)’nin ramazan ayında, 64 (%89)’ünün ramazan ayı dışında opere olduğu saptandı. Ramazan ayı ile diğer aylar arasında ameliyat sayısı açısından anlamlı bir farklılık saptanmadı (p >0,05). Olguların kış, ilkbahar, yaz ve sonbahar mevsiminde görülme sıklıkları sırası ile 12 (%16,7), 21 (%29,2), 23 (%31,9) ve 16 (%22,2) idi. Mevsimlere göre vaka sıklığı açısından anlamlı bir farklılık yoktu (p >0,05).
Sonuç: Ramazan ayının ve mevsimsel farklılıkların peptik ülser perforasyonlarının sıklığı ve klinik prognozu üzerine olumsuz bir risk faktörü teşkil etmediği saptanmıştır.
Anahtar Kelimeler
Kaynakça
- Søreide, K., Thorsen, K., Harrison, E. M., Bingener, J., Møller, M. H., Ohene-Yeboah, M., Søreide, J. A. Perforated peptic ulcer. The Lancet, 2015; 386(10000): 1288-1298. https://doi.org/10.1016/S0140-6736(15)00276-7
- Jennings DJ, Patterson S. "Peptic ulcer disease." Gastroenterology Nursing 2019;42 (5): 451-454. doi: 10.1097/ SGA.0000000000000478
- Yawar B, Marzouk A. M, Ali H, Ghorab T. M, Asim A, Bahli Z, Fleville S. Seasonal Variation of Presentation of Perforated Peptic Ulcer Disease: An Overview of Patient Demographics, Management and Outcomes. Cureus, 2021;13(11). e19618. doi: 10.7759/cureus.19618.
- Soreide K, Thorsen K, Soreide JA. Strategies to improve the out come of emergency surgery for perforated peptic ulcer. Br J Surg 2014; 101(1): 51-64.
- Wissam Jaffar Altaee, Safa M. Mahdi Alobaidi, The Effect of Ramadan Fasting on Duedenal Ulcer Perforation, The Iraqı Postgraduate Medıcal Journal 2011;10(3);381-387
- Gökakın AK, Atabey M, Koyuncu A, Topçu Ö, Aydin C, Akgöl G. The impact of Ramadan on peptic ulcer perforation. Ulusal Travma Ve Acıl Cerrahı Dergısı-Turkısh Journal Of Trauma & Emergency Surgery, 2012; 18(4). Doi: 10.5505/tjtes.2012.61257.
- Kanotra R, Ahmed M, Patel N, Thakkar B, Solanki S, Tareen S, Das, A. Seasonal variations and trends in hospitalization for peptic ulcer disease in the United States: a 12-year analysis of the nationwide inpatient sample. Cureus, 2016; 8(10). e854. doi: 10.7759/cureus.854.
- Igor Melnick, Oleg A Krishtal, William F. Colmers, Integration of energy homeostasis and stress by parvocellular neurons in rat hypothalamic paraventricular nucleus, J Physiol. 2020 Mar;598(5):1073-1092
- Al-Kaabi S, Butt MT, Taweel M, ve ark. Effect of Ramadan fasting on peptic ulcer disease. Indian Journal of Gastroenterology, 01 Jan 2004, 23(1):35
- Mehmet Akif Üstüner, Enver İlhan, Abdullah Şenlikçi, ve ark. Peptik Ülser Perforasyonlarında Morbidite ve Mortaliteye Etki Eden Faktörler, İzmir Eğitim ve Araştırma Hastanesi Tıp Dergisi,2013;17: 37-43
- Eisner, F., Hermann, D., Bajaeifer, K., Glatzle, J., Königsrainer, A., & Küper, MA (2017). Gastric Ulcer Complications after the Introduction of Proton Pump Inhibitors into Clinical Routine: 20-Year Experience, Visc Med. 2017;33: 221–226 doı: 10.1159/000475450
- Melcarne, L., García-Iglesias, P., & Calvet, X. (2016). Management of NSAID-associated peptic ulcer disease. Expert Review of Gastroenterology & Hepatology, 10(6), 723-733.
- A. Kocakucak, Does Ramadan fasting contribute tothe increase of peptic ulcer perforations ? European Review for Medical and Pharmacological Sciences, 2017; 21: 150-154.
- Rahman U, Salam F, Ishaq M.A. Effect of ramadan fasting on peptic ulcer disease and peptic perforation,Portal Regional da BVS , 2016; 27 (5): 36-39
- Abdoulhossein Davoodabadi, Hossein Akbari, Mohammd Ghasembandi, ve ark. Does Ramadan Fasting Increase Duodenal Ulcer Perforation?, J Fasting Health. 2016; 4(1): 25-31
- Bener A, Derbala MF, Al-Kaabi S, ve ark. Frequency of peptic ulcer disease during and after Ramadan in a United Arab Emirates hospital. East Mediterr Health J 2006;12: 105-11.
- Da-Yun Liu, An-Ning Gao, Guo-Du Tang, ve ark. Relationship between onset of peptic ulcer and meteorological factors, World J Gastroenterol 2006; 12(9):1463-1467
- Bakhat Yawar, Ahmed M. Marzouk, Heba Ali, ve ark. Seasonal Variation of Presentation of Perforated Peptic Ulcer Disease: An Over view of Patient Demographics, Management and Out comes, Cureus 2021;13(11): e19618. DOI 10.7759 /cureus.19618
- Roberto Manfredini, Roberto De Giorgio, Michael H Smolensky, ve ark. Seasonal pattern of peptic ulcer hospitalizations: analysis of the hospital discharge data of the Emilia-Romagna region of Italy, BMC Gastroenterology 2010; 10:37
- Tolga Kalaycı, Ümit Haluk İliklerden, Our Clinical Experiments of Peptic Ulcer Perforation with Literature Approache, Van Tıp Derg 2020; 27(3): 335-339
- Thorsen K, Soreide JA, Kvaloy JT, ve ark. Epidemiology of perforated peptic ulcer: age and gender adjusted analysis of incidence and mortality. World J Gastroenterol 2013; 19(3): 347-354.
- Sari, Y. E, Unluoglu, I, Cavusoglu, Y, Bilge, U. Inappropriate drug use rates of geriatric patients attending to a university hospital cardiology policlinic. Nigerian Journal of Clinical Practice 2021; 24(11), 1719.
- Kossioni, A, Bellou, O. Eating habits in older people in Greece: The role of age, dental status and chewing difficulties. Archives of gerontology and geriatrics, 2011;52(2), 197-201.
- Lau, J. Y, Sung, J, Hill, C, Henderson, C, Howden, C. W, Metz, D. C. Systematic review of the epidemiology of complicated peptic ulcer disease: incidence, recurrence, risk factors and mortality. Digestion, 2011; 84(2), 102-113.
- Sivaram, P, Sreekumar, A. Preoperative factors influencing mortality and morbidity in peptic ulcer perforation. European Journal of Trauma and Emergency Surgery, 2018; 44(2), 251-257.
Öz
Objective: Peptic ulcer perforation is one of the most important surgical emergencies. In this study, it was aimed to evaluate the possible effects of Ramadan and the seasons on peptic ulcer perforations.
Materials and Methods: The patients operated for peptic ulcer perforation in our clinic were evaluated retrospectively. Demographic and clinical data of the patients, date of operation, surgical technique performed and post-operative follow-up data were recorded. In addition, the incidence and clinic of the cases during the Ramadan were recorded. The seasonal and monthly comparisons of the cases were made with the obtained data.
Results: A total of 72 patients were included in the study. Of the patients, 14 (19%) were female and 58 (81%) were male. The mean age of female patients was 64±23 years, and the mean age of male patients was 44±17 years (p <0,001). It was determined that 8 (11%) of the patients were operated during the Ramadan and 64 (89%) of them were operated outside of the Ramadan. No significant difference was found between the Ramadan and the other months in terms of the number of operations (p>0,05). The frequencies of the cases in winter, spring, autumn and winter seasons were 12 (16.7%), 21 (29.2%), 23 (31.9%), and 16 (22.2%), respectively. There was no significant difference in the case frequency according to the seasons (p >0,05). The incidence of the cases in winter, spring, summer and autumn seasons, respectively; were 12 (16.7%), 21 (29.2%), 23 (31.9%) and 16 (22.2%).
Conclusion: It was determined that the Ramadan and seasonal differences do not constitute a negative risk factor on the frequency and clinical prognosis of the peptic ulcer perforations.
Anahtar Kelimeler
Kaynakça
- Søreide, K., Thorsen, K., Harrison, E. M., Bingener, J., Møller, M. H., Ohene-Yeboah, M., Søreide, J. A. Perforated peptic ulcer. The Lancet, 2015; 386(10000): 1288-1298. https://doi.org/10.1016/S0140-6736(15)00276-7
- Jennings DJ, Patterson S. "Peptic ulcer disease." Gastroenterology Nursing 2019;42 (5): 451-454. doi: 10.1097/ SGA.0000000000000478
- Yawar B, Marzouk A. M, Ali H, Ghorab T. M, Asim A, Bahli Z, Fleville S. Seasonal Variation of Presentation of Perforated Peptic Ulcer Disease: An Overview of Patient Demographics, Management and Outcomes. Cureus, 2021;13(11). e19618. doi: 10.7759/cureus.19618.
- Soreide K, Thorsen K, Soreide JA. Strategies to improve the out come of emergency surgery for perforated peptic ulcer. Br J Surg 2014; 101(1): 51-64.
- Wissam Jaffar Altaee, Safa M. Mahdi Alobaidi, The Effect of Ramadan Fasting on Duedenal Ulcer Perforation, The Iraqı Postgraduate Medıcal Journal 2011;10(3);381-387
- Gökakın AK, Atabey M, Koyuncu A, Topçu Ö, Aydin C, Akgöl G. The impact of Ramadan on peptic ulcer perforation. Ulusal Travma Ve Acıl Cerrahı Dergısı-Turkısh Journal Of Trauma & Emergency Surgery, 2012; 18(4). Doi: 10.5505/tjtes.2012.61257.
- Kanotra R, Ahmed M, Patel N, Thakkar B, Solanki S, Tareen S, Das, A. Seasonal variations and trends in hospitalization for peptic ulcer disease in the United States: a 12-year analysis of the nationwide inpatient sample. Cureus, 2016; 8(10). e854. doi: 10.7759/cureus.854.
- Igor Melnick, Oleg A Krishtal, William F. Colmers, Integration of energy homeostasis and stress by parvocellular neurons in rat hypothalamic paraventricular nucleus, J Physiol. 2020 Mar;598(5):1073-1092
- Al-Kaabi S, Butt MT, Taweel M, ve ark. Effect of Ramadan fasting on peptic ulcer disease. Indian Journal of Gastroenterology, 01 Jan 2004, 23(1):35
- Mehmet Akif Üstüner, Enver İlhan, Abdullah Şenlikçi, ve ark. Peptik Ülser Perforasyonlarında Morbidite ve Mortaliteye Etki Eden Faktörler, İzmir Eğitim ve Araştırma Hastanesi Tıp Dergisi,2013;17: 37-43
- Eisner, F., Hermann, D., Bajaeifer, K., Glatzle, J., Königsrainer, A., & Küper, MA (2017). Gastric Ulcer Complications after the Introduction of Proton Pump Inhibitors into Clinical Routine: 20-Year Experience, Visc Med. 2017;33: 221–226 doı: 10.1159/000475450
- Melcarne, L., García-Iglesias, P., & Calvet, X. (2016). Management of NSAID-associated peptic ulcer disease. Expert Review of Gastroenterology & Hepatology, 10(6), 723-733.
- A. Kocakucak, Does Ramadan fasting contribute tothe increase of peptic ulcer perforations ? European Review for Medical and Pharmacological Sciences, 2017; 21: 150-154.
- Rahman U, Salam F, Ishaq M.A. Effect of ramadan fasting on peptic ulcer disease and peptic perforation,Portal Regional da BVS , 2016; 27 (5): 36-39
- Abdoulhossein Davoodabadi, Hossein Akbari, Mohammd Ghasembandi, ve ark. Does Ramadan Fasting Increase Duodenal Ulcer Perforation?, J Fasting Health. 2016; 4(1): 25-31
- Bener A, Derbala MF, Al-Kaabi S, ve ark. Frequency of peptic ulcer disease during and after Ramadan in a United Arab Emirates hospital. East Mediterr Health J 2006;12: 105-11.
- Da-Yun Liu, An-Ning Gao, Guo-Du Tang, ve ark. Relationship between onset of peptic ulcer and meteorological factors, World J Gastroenterol 2006; 12(9):1463-1467
- Bakhat Yawar, Ahmed M. Marzouk, Heba Ali, ve ark. Seasonal Variation of Presentation of Perforated Peptic Ulcer Disease: An Over view of Patient Demographics, Management and Out comes, Cureus 2021;13(11): e19618. DOI 10.7759 /cureus.19618
- Roberto Manfredini, Roberto De Giorgio, Michael H Smolensky, ve ark. Seasonal pattern of peptic ulcer hospitalizations: analysis of the hospital discharge data of the Emilia-Romagna region of Italy, BMC Gastroenterology 2010; 10:37
- Tolga Kalaycı, Ümit Haluk İliklerden, Our Clinical Experiments of Peptic Ulcer Perforation with Literature Approache, Van Tıp Derg 2020; 27(3): 335-339
- Thorsen K, Soreide JA, Kvaloy JT, ve ark. Epidemiology of perforated peptic ulcer: age and gender adjusted analysis of incidence and mortality. World J Gastroenterol 2013; 19(3): 347-354.
- Sari, Y. E, Unluoglu, I, Cavusoglu, Y, Bilge, U. Inappropriate drug use rates of geriatric patients attending to a university hospital cardiology policlinic. Nigerian Journal of Clinical Practice 2021; 24(11), 1719.
- Kossioni, A, Bellou, O. Eating habits in older people in Greece: The role of age, dental status and chewing difficulties. Archives of gerontology and geriatrics, 2011;52(2), 197-201.
- Lau, J. Y, Sung, J, Hill, C, Henderson, C, Howden, C. W, Metz, D. C. Systematic review of the epidemiology of complicated peptic ulcer disease: incidence, recurrence, risk factors and mortality. Digestion, 2011; 84(2), 102-113.
- Sivaram, P, Sreekumar, A. Preoperative factors influencing mortality and morbidity in peptic ulcer perforation. European Journal of Trauma and Emergency Surgery, 2018; 44(2), 251-257.
Ayrıntılar
| Birincil Dil | Türkçe |
|---|---|
| Konular | Klinik Tıp Bilimleri |
| Bölüm | Araştırma Makaleleri |
| Yazarlar | |
| Yayımlanma Tarihi | 31 Ağustos 2022 |
| Gönderilme Tarihi | 4 Mayıs 2022 |
| Yayımlandığı Sayı | Yıl 2022 Cilt: 11 Sayı: 2 |
