An overview about Laboratory Rodents, Digestive Physiology and Important Issues regarding Their Nutrition
Abstract
The current trends in biomedical research gloabally rely upon experimental animals for their pivotal contribution in proper designs of experiments to understand the underlying mechanisms of various diseases.. These animals which are mostly rodents; are broadly preferred in biomedical research for certain characters like well established gene maps, easy adaptibility and ability to produce large number of offsprings at breeding. Besides, these animals are well known for high compliance to different diets beacuse of their characteristic digestive system structure, and high susceptibility to targeted non-infectious or genetic diseases which may cause harm to humans. Rodents are fed with different diets that meet their maintenance and productivity requirements specific to each specie and strain, highly depending upon the production or experimental purposes. Commercial diets in pellet or extruded form consisting of various feed raw materials of plant and / or animal origin, are the most widely used diets for feeding and special diets are also prepared according to the requirements of research. This review deals in comprehending the details about orgin, history, feeding behaviours and strains of variously used experimental animals. Besides, nutrient requirements of this animals; characteristics, type, content, physical form of diet and effects of environmental factors on their diet have been discussed.
Keywords
References
- [1] Stokes WS. Humane endpoints for laboratory animals used in regulatory testing, ILAR Journal, 2002; 43: S31-S38.
- [2] Singh VP., Pratap K., Sinha J., Desiraju K., Bahal D., Kukreti R. Critical evaluation of challenges and future use of animals in experimentation for biomedical research. England: SAGE Publications 2016.
- [3] Barnard DE., Lewis SM., Teter BB., Thigpen JE. Open-and closed-formula laboratory animal diets and their importance to research, Journal of the American Association for Laboratory Animal Science 2009; 48: 709-713.
Abstract
References
- [1] Stokes WS. Humane endpoints for laboratory animals used in regulatory testing, ILAR Journal, 2002; 43: S31-S38.
- [2] Singh VP., Pratap K., Sinha J., Desiraju K., Bahal D., Kukreti R. Critical evaluation of challenges and future use of animals in experimentation for biomedical research. England: SAGE Publications 2016.
- [3] Barnard DE., Lewis SM., Teter BB., Thigpen JE. Open-and closed-formula laboratory animal diets and their importance to research, Journal of the American Association for Laboratory Animal Science 2009; 48: 709-713.
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Structural Biology |
| Journal Section | REVIEWS |
| Authors | |
| Publication Date | December 15, 2020 |
| Submission Date | October 26, 2020 |
| Acceptance Date | November 24, 2020 |
| Published in Issue | Year 2020 Volume: 3 Issue: 2 |
Cite
Cited By
Swertia bimaculata moderated liver damage in mice by regulating intestine microbiota
Ecotoxicology and Environmental Safety
https://doi.org/10.1016/j.ecoenv.2023.115223
*This journal is an international refereed journal
*Our journal does not charge any article processing fees over publication process.
* This journal is online publishes 5 issues per year (January, March, June, September, December)
*This journal published in Turkish and English as open access.
* This work is licensed under a Creative Commons Attribution 4.0 International License.