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Cytotoxicity and Acetylcholinesterase inhibitory and PRAP activities of the essential oils of selected Tanacetum L. species.

Year 2015, Volume: 2 Issue: 4, 11 - 16, 28.03.2016

Kaan Polatoğlu Hüseyin Servi Yasemin Yücel Yücel Ayşe Nalbantsoy

Abstract

Essential oils obtained from flowers of Tanacetum mucroniferum Hub. - Mor. & Grierson, leaves of Tanacetum densum (Labill.) Heywood ssp. eginense Heywood, stems of Tanacetum densum (Labill.) Heywood ssp. sivasicum Hub. - Mor. & Grierson were investigated for their cytotoxicity, AChE inhibitory and PRAP activities. We have previously investigated chemical composition of these oils and we have also suspected that these oils also do have strong AChE inhibitory activities due to the insecticidal activities which we have reported for the other members of this genus. Highest activities were observed for pure oils: T. mucronifeum, T.densum ssp. sivasicum and T. densum ssp. eginense were 100.00±0.0%; 100.00±0.0% and 91.31±3.30% respectively (n=3). The observed activities were concentration dependent. Compared with the positive control α-tocopherol (3.735±0.063 AU; n=3) in same concentrations, all of the investigated oils showed low PRAP activity at the highest concentration (10 mg/mL). Highest activity was observed for T. mucroniferum (1.319±0.017 AU; n=3) at 10 mg/mL concentration.

Keywords

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References

  • Chiasson, H., Belanger, A., Bostanian, N., Vincent, C., Poliquin, A., (2001). Acaricidal properties of Artemisia absinthium and Tanacetum vulgare (Asteraceae) essential oils obtained by three methods of extraction. Journal of Economic Entomology, 94(1), 167–171.
  • Ellman, G. L., Courtney, K. D., Andres Jr., V., Featherstone, R. M. (1961). A new and rapid colorimetric determination of acetylcholinesterase activity. Biochemical Pharmacology, 7, 88–95.
  • Falcioni, G., Fedeli, D., Tiano, L., Calzuola, I., Mancinelli, L., Marsili, V., Gianfranceschi, G., 2002. Antioxidant activity of wheat sprouts extracts in vitro: inhibition of DNA oxidative damage. Journal of Food Science, 67, 2918–2922.
  • Gabel, B., Thiery, D. (1994). Nonhost plant odor (Tanacetum-vulgare, ASTERACEA) affects. The reproductive- behavior of Lobesia-botrana DEN-ET-SCHIFF (LEPIDOPTERA, TORTRICIDAE). Journal of Insect Behaviour, 7(2), 149–157.
  • Isman, M. B. (2006). Botanical insecticides deterrents, and repellents in modern agriculture and an increasingly regulated world. Annual Review of Entomology, 51, 45–66.
  • Lopez, M. D., Pascual-Villalobos, M. J. (2010). Mode of inhibition of acetylcholinesterase by monoterpenoids and implications for pest control. Industrial Crops and Products, 31, 284–288.
  • Mosmann, T. (1983). Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. Journal of Immunological Methods, 65, 55–63.
  • Nalbantsoy, A., Ayyıldız Tamis, D., Akgun, I. H., Ozturk Yalcın, T., Deliloğlu Gürhan, I., Karaboz, I. (2008). Antimicrobial and Cytotoxic Activities of Zingiber officinalis Extracts. Journal of Pharmaceutical Sciences, FABAD, 33, 76–85.
  • Palsson, K., Jaenson, T. G. T., Baeckstrom, P., Borg-Karlson, A. K. (2008). Thick repellent substances in the essential oil of Tanacetum vulgare. Journal of Medical Entomology, 45(1), 88–93.
  • Perry, N. S., Houghton, P. J., Theobald, A., Jenner, P., Perry, E. K. (2000). In-vitro Inhibition of Human Erythrocyte Acetylcholinesterase by Salvia lavandulaefolia Essential Oil and Constituent Terpenes. Journal of
  • Pharmacy and Pharmacology, 52(7), 895-9
  • Polatoglu, K., Başer, K. H. C., Gören, N., Demirci, B. (2009). The Essential Oil Composition of Tanacetum densum (Labill.) Heywood ssp. sivasicum Hub.-Mor. & Grierson from Turkey. Journal of Essential Oil Research, 21, 200-202.
  • Polatoglu, K., Demirci, B., Demirci, F., Gören, N., Başer, K. H. C. (2012a). Composition of Tanacetum densum (Labill.) Heywood ssp. eginense Heywood from Turkey. Records of Natural Products, 6(4), 402-406.
  • Polatoglu, K., Şen, A., Kandemir, A., Gören, N. (2012b). Essential oil composition and DPPH scavenging activity of endemic Tanacetum mucroniferum Hub. –Mor. & Grierson from Turkey. Journal of Essential Oil Bearing Plants, 15(1), 66-74.
  • Perry, N. S., Houghton, P. J., Theobald, A., Jenner, P., Perry, E. K. (2000). In-vitro Inhibition of Human Erythrocyte Acetylcholinesterase by Salvia lavandulaefolia Essential Oil and Constituent Terpenes. Journal of Pharmacy and Pharmacology, 52(7), 895-902.
  • Polatoğlu, K., Karakoç, Ö. C., Yücel, Y. Y., Demirci, B., Gören, N., Başer, K. H. C. (2015a). Composition, insecticidal activity and other biological activities of Tanacetum abrotanifolium Druce. essential oil. Industrial Crops and Products, 71, 7-14
  • Polatoğlu, K., Karakoç, Ö. C., Demirci, B., Gören, N., & Can Başer, K. H. (2015b). Sitophilus granarius L.(Coleoptera) Toxicity and Biological Activities of the Essential Oils of Tanacetum macrophyllum (Waldst. &Kit.) Schultz Bip. Journal of oleo science, 64(8), 881-893.
  • Villaverde, J. J., Sevilla-Morán, B., Sandín-Espâna, P., López-Goti, C., Alonso-Prados, J. L. (2014). Biopesticides in the framework of the European Pesticide Regulation (EC) No. 1107/2009. Pest Management Science, 70, 2–5.
  • Wandahwa, P., Van Ranst, E., Van Damme, P., (1996). Pyrethrum (Chrysanthemum cinerariaefolium Vis.) cultivation in West Kenya: origin, ecological conditions and management. Industrial Crops and Products, 5, 307–322.

Year 2015, Volume: 2 Issue: 4, 11 - 16, 28.03.2016

Kaan Polatoğlu Hüseyin Servi Yasemin Yücel Yücel Ayşe Nalbantsoy

Abstract

References

  • Chiasson, H., Belanger, A., Bostanian, N., Vincent, C., Poliquin, A., (2001). Acaricidal properties of Artemisia absinthium and Tanacetum vulgare (Asteraceae) essential oils obtained by three methods of extraction. Journal of Economic Entomology, 94(1), 167–171.
  • Ellman, G. L., Courtney, K. D., Andres Jr., V., Featherstone, R. M. (1961). A new and rapid colorimetric determination of acetylcholinesterase activity. Biochemical Pharmacology, 7, 88–95.
  • Falcioni, G., Fedeli, D., Tiano, L., Calzuola, I., Mancinelli, L., Marsili, V., Gianfranceschi, G., 2002. Antioxidant activity of wheat sprouts extracts in vitro: inhibition of DNA oxidative damage. Journal of Food Science, 67, 2918–2922.
  • Gabel, B., Thiery, D. (1994). Nonhost plant odor (Tanacetum-vulgare, ASTERACEA) affects. The reproductive- behavior of Lobesia-botrana DEN-ET-SCHIFF (LEPIDOPTERA, TORTRICIDAE). Journal of Insect Behaviour, 7(2), 149–157.
  • Isman, M. B. (2006). Botanical insecticides deterrents, and repellents in modern agriculture and an increasingly regulated world. Annual Review of Entomology, 51, 45–66.
  • Lopez, M. D., Pascual-Villalobos, M. J. (2010). Mode of inhibition of acetylcholinesterase by monoterpenoids and implications for pest control. Industrial Crops and Products, 31, 284–288.
  • Mosmann, T. (1983). Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. Journal of Immunological Methods, 65, 55–63.
  • Nalbantsoy, A., Ayyıldız Tamis, D., Akgun, I. H., Ozturk Yalcın, T., Deliloğlu Gürhan, I., Karaboz, I. (2008). Antimicrobial and Cytotoxic Activities of Zingiber officinalis Extracts. Journal of Pharmaceutical Sciences, FABAD, 33, 76–85.
  • Palsson, K., Jaenson, T. G. T., Baeckstrom, P., Borg-Karlson, A. K. (2008). Thick repellent substances in the essential oil of Tanacetum vulgare. Journal of Medical Entomology, 45(1), 88–93.
  • Perry, N. S., Houghton, P. J., Theobald, A., Jenner, P., Perry, E. K. (2000). In-vitro Inhibition of Human Erythrocyte Acetylcholinesterase by Salvia lavandulaefolia Essential Oil and Constituent Terpenes. Journal of
  • Pharmacy and Pharmacology, 52(7), 895-9
  • Polatoglu, K., Başer, K. H. C., Gören, N., Demirci, B. (2009). The Essential Oil Composition of Tanacetum densum (Labill.) Heywood ssp. sivasicum Hub.-Mor. & Grierson from Turkey. Journal of Essential Oil Research, 21, 200-202.
  • Polatoglu, K., Demirci, B., Demirci, F., Gören, N., Başer, K. H. C. (2012a). Composition of Tanacetum densum (Labill.) Heywood ssp. eginense Heywood from Turkey. Records of Natural Products, 6(4), 402-406.
  • Polatoglu, K., Şen, A., Kandemir, A., Gören, N. (2012b). Essential oil composition and DPPH scavenging activity of endemic Tanacetum mucroniferum Hub. –Mor. & Grierson from Turkey. Journal of Essential Oil Bearing Plants, 15(1), 66-74.
  • Perry, N. S., Houghton, P. J., Theobald, A., Jenner, P., Perry, E. K. (2000). In-vitro Inhibition of Human Erythrocyte Acetylcholinesterase by Salvia lavandulaefolia Essential Oil and Constituent Terpenes. Journal of Pharmacy and Pharmacology, 52(7), 895-902.
  • Polatoğlu, K., Karakoç, Ö. C., Yücel, Y. Y., Demirci, B., Gören, N., Başer, K. H. C. (2015a). Composition, insecticidal activity and other biological activities of Tanacetum abrotanifolium Druce. essential oil. Industrial Crops and Products, 71, 7-14
  • Polatoğlu, K., Karakoç, Ö. C., Demirci, B., Gören, N., & Can Başer, K. H. (2015b). Sitophilus granarius L.(Coleoptera) Toxicity and Biological Activities of the Essential Oils of Tanacetum macrophyllum (Waldst. &Kit.) Schultz Bip. Journal of oleo science, 64(8), 881-893.
  • Villaverde, J. J., Sevilla-Morán, B., Sandín-Espâna, P., López-Goti, C., Alonso-Prados, J. L. (2014). Biopesticides in the framework of the European Pesticide Regulation (EC) No. 1107/2009. Pest Management Science, 70, 2–5.
  • Wandahwa, P., Van Ranst, E., Van Damme, P., (1996). Pyrethrum (Chrysanthemum cinerariaefolium Vis.) cultivation in West Kenya: origin, ecological conditions and management. Industrial Crops and Products, 5, 307–322.
There are 19 citations in total.

Details

Primary Language English
Journal Section Articles
Authors

Kaan Polatoğlu

Hüseyin Servi This is me

Yasemin Yücel Yücel This is me

Ayşe Nalbantsoy

Publication Date March 28, 2016
Published in Issue Year 2015 Volume: 2 Issue: 4

Cite

APA Polatoğlu, K., Servi, H., Yücel Yücel, Y., Nalbantsoy, A. (2016). Cytotoxicity and Acetylcholinesterase inhibitory and PRAP activities of the essential oils of selected Tanacetum L. species. Natural Volatiles and Essential Oils, 2(4), 11-16.
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