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Kafeinin İnsan Sağlığı Üzerindeki Etkileri

Year 2017, Volume:6 ICAFOF Special Issue, 297 - 305, 21.12.2017
https://doi.org/10.17100/nevbiltek.331845

Abstract

Kafein, tüm dünyada en çok tüketilen psikoaktif maddelerden biridir.
Tarihsel olarak çay ve soda kafein içeren en eski içeceklerdir. Son zamanlarda,
enerji içecekleri, özel kahve, patates cipsi, sakız ve şekerler gibi kafein
içeren gıda üretiminin çeşitliliğinde önemli artışlar olmuştur. Bu nedenle,
kafein içeren içeceklerin tüketimi dünyada çapında önemli düzeylere ulaşmıştır.
Son yıllarda kafeinin tüketimi, ilaçlarla karşılaştırıldığında daha yüksek
oranlara sahiptir. Dünya nüfusunun yaklaşık % 80'i hergün kafein içeren
içecekler tüketmektedir. Dünya çapında, kahve (%71) en çok tüketilen kafein
içerikli içecek olmasıyla birlikte, alkolsüz içecekler (%16) ve çay (%12) bunu
takip etmektedir. Gelişen teknoloji ve yeniliklerle birlikte gıda endüstrisinde
kafein tüketimi arasında önemli bir artış vardır.  Bu çalışmada kafein tüketiminin, kardiyovasküler
sistem, anksiyete, hafıza, uyku, depresyon ve agresyon açısından insan sağılığı
üzerindeki etkileri incelenmiştir.
Kafeinin
içeren içeceklere artan talebin, genel olarak insan sağlığı üzerine olumlu
etkileri olduğu düşünülmektedir. 

References

  • Referans1 Amendola, C.A., Gabrieli, J.D.F., Lieberman, H.R., Caffeine’s effects on performance and mood are independent of age and gender. Nutr. Neurosci. 1, 269–280. 1998
  • Referans2 Amaresh, Nirmala, A. R. Mullaicharam, and Mohanned Abdueghafour El-Khider. "Chemistry and pharmacology of caffeine in different types of tea leaves." International Journal of Nutrition, Pharmacology, Neurological Diseases 1.2 :110, 2011
  • Referans3 Bonita JS, Mandarano M, Shuta D, Vinson J. Coffee and cardiovascular disease: in vitro, cellular, animal, and human studies. Pharmacol Res; 55:187–98, 2007
  • Referans4 Cano-Marquina, A. et al. The impact of coffee on health. Maturitas 75, 7–21:6, 2013
  • Referans5 Chen, Jiang-Fan, Holger K. Eltzschig, and Bertil B. Fredholm. "Adenosine receptors as drug targets—what are the challenges?" Nature reviews Drug discovery 12.4: (265-286, 2013
  • Referans6 Christensen, Larry, and Ross Burrows. "Dietary treatment of depression." Behavior Therapy 21.2 : 183-193, 1990
  • Referans7 de Mejia, Elvira Gonzalez, and Marco Vinicio Ramirez-Mares. "Impact of caffeine and coffee on our health." Trends in Endocrinology & Metabolism 25.10: 489-492, 2014
  • Referans8 Dews, Peter B. "Caffeine." Annual review of nutrition 2.1: 323-341, 1982 Referans D.R. Mazzotti, Diego Robles, et al. "Effects of the adenosine deaminase polymorphism and caffeine intake on sleep parameters in a large population sample." Sleep 34.3: 399-402, 2011
  • Referans9 Dunwiddie, Thomas V., and Susan A. Masino. "The role and regulation of adenosine in the central nervous system." Annual review of neuroscience 24.1: 31-55, 2001 Referans Edwards, Bonnie. America's Favorite Drug: Coffee and Your Health. Berkeley: Odonian Press, 1992
  • Referans10 Frary, Carol D., Rachel K. Johnson, and Min Qi Wang. "Food sources and intakes of caffeine in the diets of persons in the United States." Journal of the American Dietetic Association 105.1: 110-113,2005
  • Referans11 Friedman, M., Overview of antibacterial, antitoxin, antiviral, and antifungal activities of tea flavonoids and teas. Mol. Nutr. Food Res. 51, 116–134, 2007
  • Referans12 Garattini, Silvio, ed. Caffeine, Coffee and Healht. New York: Raven Press, 1993
  • Referans13 Graham TE, Helge JW, MacLean DA, et al. Caffeine ingestion does not alter carbohydrate or fat metabolism in human skeletal muscle during exercise. J Physiol (London) 529: 837-47, 2000
  • Referans14 Graham TE, Spriet LL. Performance and metabolic responses to a high caffeine dose during prolonged exercise. J Appl Physiol 71: 2292-8, 1991
  • Referans15 Graham TE, Spriet LL. Metabolic, catecholamine, and exercise performance responses to various doses of caffeine. J Appl Physiol 78: 867-74,1995
  • Referans16 Greer F, McLean C, Graham TE. Caffeine, performance and metabolism during repeated Wingate exercise tests. J Appl Physiol 85: 1502-8, 1998
  • Referans17 Greer F, Friars D, Graham TE. Comparison of caffeine and theophylline ingestion: exercise metabolism and endurance. J Appl Physiol 89: 1837-44, 2000
  • Referans18 Heckman, M.A. et al. Energy drinks: an assessment of their market size, consumer demographics, ingredient profile, functionality, and regulations in the United States. Compr. Rev. Food Sci. Food Safety 9, 303–317, 2010

  • Referans19 Heatherley, S.V., Hayward, R.C., Seers, H.E., Rogers, P.J., Cognitive and psychomotor performance, mood, and pressor effects of caffeine after 4, 6 and 8 h caffeine abstinence. Psychopharmacology 178, 461–470, 2005
  • Referans20 Huang, Zhi-Li, et al. "Adenosine A2A, but not A1, receptors mediate the arousal effect of caffeine." Nat Neurosci 8.7: 858-9, 2005
  • Referans21 Jackman M, Wendling P, Friars D, et al. Metabolic, catecholamine, and endurance responses to caffeine during intense exercise. J Appl Physiol; 81: 1658-63, 1996
  • Referans22 James, Jack E. Caffeine and Healhty. London: Harcourt Brace Jovanovich, 1991
  • Referans23 Kovacs, E.M., Mela, D.J., Metabolically active functional food ingredients for weight control. Obes. Rev. 7, 59–78, 2006
  • Referans24 Loke, Wing Hong, J. V. Hinrichs, and M. M. Ghoneim. "Caffeine and diazepam: separate and combined effects on mood, memory, and psychomotor performance." Psychopharmacology 87.3: 344-350,1985
  • Referans25 NCA, National Coffee Drinking Trends 2012, National Coffee Association, 2012

  • Referans26 Nehlig, A., Are we dependent upon coffee and caffeine. A review on human and animal data. Neurosci. Biobehav. Rev. 23, 563–576, 1999
  • Referans27 Neil, John F., et al. "Caffeinism complicating hypersomnic depressive episodes." Comprehensive psychiatry 19.4: 377-385, 1978
  • Referans28 O’Keefe, J.H. et al. Effects of habitual coffee consumption on cardiometabolic disease, cardiovascular health, and all-cause mortality. J. Am. Coll. Cardiol. 62, 1043–1051, 2013
  • Referans29 Regestein, Quentin R. "Pathologic sleepiness induced by caffeine." The American journal of medicine 87.5: 586-588, 1989
  • Referans30 Roache, J. D. & Griffiths, R. R. Interactions of diazepam and caffeine: behavioral and subjective dose effects in humans. Pharmacology Biochemistry and Behavior, 26, 801–812, 1987
  • Referans31 Segal, Harold B. The Vienna Coffeehouse Wits: 1890-1938. West Lafayette, Ind.: Purdue University Press, the diets of persons in the United States. J. Am. Diet Assoc. 105, 110–113, 1993
  • Referans32 Spriet LL, MacLean DA, Dyck DJ, et al. Caffeine ingestion and muscle metabolism during prolonged exercise in humans. Am J Physiol; 262 (6 Pt 1): E891-E898, 1992
  • Referans33 Stated, Transcendental Meditation Technique Unless Otherwise. "scientific research on maharishi’s transcendental meditation and tm-sidhi program volumes 1-6. Journal of Physiology 221 (1971): 795-799, 1971
  • Referans34 Terry, W.S., Phifer, B., Caffeine and memory performance on the AVLT. J. Clin. Psychol. 42, 860–863. 1986
  • Referans35 Thelle, Dag S., Egil Arnesen, and Olav H. Førde. "The Tromsö heart study: does coffee raise serum cholesterol?." New England Journal of Medicine 308.24: 1454-1457, 1983
  • Referans36 Van Soeren MH, Graham TE. Effect of caffeine on metabolism, exercise endurance, and catecholamine responses after withdrawal. J Appl Physiol; 85 (1493): 1501, 1998
  • Referans37 Van Soeren MH, Sathasivam P, Spriet LL, et al. Caffeine metabolism and epinephrine responses during exercise in users and nonusers. J Appl Physiol; 75: 805-12 Y. Tank et al., '' Effect of Xanthine Derivatives on Hippocampal Long-term Potentiation,'' Brain Research 522 : 63-68, 1993
  • Referans38 V. E. Mitchell et all., '' Drugs and Places: Effects of Caffeine on Conginitive Performance Pyhchological Reports, 35: 875-83, 1974
  • Referans39 Williams, L. Shawn. "Effects of Low-Level Caffeine Consumption on Long-term Memory Recall of Southern College Students." 1992
  • Referans40 “In the context of learning and memory, it is interesting to note that xanthines, such as theophylline, enhanced long-term potentiation, an elector-pyhsiological model of memory” in guinea pigs. Y. Tank et al., “Effect of Xanthine Derivativeson Hippocampal Long-term Potentiation,” Brain Research 522: 63-68, 1990
  • Referans41 Williams, L. Shawn. "Effects of Low-Level Caffeine Consumption on Long-term Memory Recall of Southern College Students." 1992

Effects of Caffeine on Human Health

Year 2017, Volume:6 ICAFOF Special Issue, 297 - 305, 21.12.2017
https://doi.org/10.17100/nevbiltek.331845

Abstract

Caffeine
is one of the most broadly consumed psychoactive material all over the world
[1] .
Historically, tea and soda are the most oldest beverages including caffeine.
Recently, variation of food production, which
comprise caffeine, has increased such as energy drinks, specialist coffee,
potato chips, gum and candy bar
[8] . Therefore, the
consumption of caffeine-containing drinks has raised remarkably throughout the
world. Indeed, in recent years, the consumption of caffeine is higher than any
other drug. Nearly 80% of the world’s population consumes caffeine-contaning
products ever day, with tea (12%), soft drink (16%) and coffee (%71) being the
most widely consumed
[8,9]. There is an significant increase in caffeine consumption throught
last century with developing technology and innovative evolution in food
industry. Actually, the rising demanding of the caffeine contaning productions
has brought along with its likley effects on human health. The present study
reviewed the effects of caffeine consumption on human healthy in terms of
cardiovascular system, anxiety, memory, sleep, depression and agression.

References

  • Referans1 Amendola, C.A., Gabrieli, J.D.F., Lieberman, H.R., Caffeine’s effects on performance and mood are independent of age and gender. Nutr. Neurosci. 1, 269–280. 1998
  • Referans2 Amaresh, Nirmala, A. R. Mullaicharam, and Mohanned Abdueghafour El-Khider. "Chemistry and pharmacology of caffeine in different types of tea leaves." International Journal of Nutrition, Pharmacology, Neurological Diseases 1.2 :110, 2011
  • Referans3 Bonita JS, Mandarano M, Shuta D, Vinson J. Coffee and cardiovascular disease: in vitro, cellular, animal, and human studies. Pharmacol Res; 55:187–98, 2007
  • Referans4 Cano-Marquina, A. et al. The impact of coffee on health. Maturitas 75, 7–21:6, 2013
  • Referans5 Chen, Jiang-Fan, Holger K. Eltzschig, and Bertil B. Fredholm. "Adenosine receptors as drug targets—what are the challenges?" Nature reviews Drug discovery 12.4: (265-286, 2013
  • Referans6 Christensen, Larry, and Ross Burrows. "Dietary treatment of depression." Behavior Therapy 21.2 : 183-193, 1990
  • Referans7 de Mejia, Elvira Gonzalez, and Marco Vinicio Ramirez-Mares. "Impact of caffeine and coffee on our health." Trends in Endocrinology & Metabolism 25.10: 489-492, 2014
  • Referans8 Dews, Peter B. "Caffeine." Annual review of nutrition 2.1: 323-341, 1982 Referans D.R. Mazzotti, Diego Robles, et al. "Effects of the adenosine deaminase polymorphism and caffeine intake on sleep parameters in a large population sample." Sleep 34.3: 399-402, 2011
  • Referans9 Dunwiddie, Thomas V., and Susan A. Masino. "The role and regulation of adenosine in the central nervous system." Annual review of neuroscience 24.1: 31-55, 2001 Referans Edwards, Bonnie. America's Favorite Drug: Coffee and Your Health. Berkeley: Odonian Press, 1992
  • Referans10 Frary, Carol D., Rachel K. Johnson, and Min Qi Wang. "Food sources and intakes of caffeine in the diets of persons in the United States." Journal of the American Dietetic Association 105.1: 110-113,2005
  • Referans11 Friedman, M., Overview of antibacterial, antitoxin, antiviral, and antifungal activities of tea flavonoids and teas. Mol. Nutr. Food Res. 51, 116–134, 2007
  • Referans12 Garattini, Silvio, ed. Caffeine, Coffee and Healht. New York: Raven Press, 1993
  • Referans13 Graham TE, Helge JW, MacLean DA, et al. Caffeine ingestion does not alter carbohydrate or fat metabolism in human skeletal muscle during exercise. J Physiol (London) 529: 837-47, 2000
  • Referans14 Graham TE, Spriet LL. Performance and metabolic responses to a high caffeine dose during prolonged exercise. J Appl Physiol 71: 2292-8, 1991
  • Referans15 Graham TE, Spriet LL. Metabolic, catecholamine, and exercise performance responses to various doses of caffeine. J Appl Physiol 78: 867-74,1995
  • Referans16 Greer F, McLean C, Graham TE. Caffeine, performance and metabolism during repeated Wingate exercise tests. J Appl Physiol 85: 1502-8, 1998
  • Referans17 Greer F, Friars D, Graham TE. Comparison of caffeine and theophylline ingestion: exercise metabolism and endurance. J Appl Physiol 89: 1837-44, 2000
  • Referans18 Heckman, M.A. et al. Energy drinks: an assessment of their market size, consumer demographics, ingredient profile, functionality, and regulations in the United States. Compr. Rev. Food Sci. Food Safety 9, 303–317, 2010

  • Referans19 Heatherley, S.V., Hayward, R.C., Seers, H.E., Rogers, P.J., Cognitive and psychomotor performance, mood, and pressor effects of caffeine after 4, 6 and 8 h caffeine abstinence. Psychopharmacology 178, 461–470, 2005
  • Referans20 Huang, Zhi-Li, et al. "Adenosine A2A, but not A1, receptors mediate the arousal effect of caffeine." Nat Neurosci 8.7: 858-9, 2005
  • Referans21 Jackman M, Wendling P, Friars D, et al. Metabolic, catecholamine, and endurance responses to caffeine during intense exercise. J Appl Physiol; 81: 1658-63, 1996
  • Referans22 James, Jack E. Caffeine and Healhty. London: Harcourt Brace Jovanovich, 1991
  • Referans23 Kovacs, E.M., Mela, D.J., Metabolically active functional food ingredients for weight control. Obes. Rev. 7, 59–78, 2006
  • Referans24 Loke, Wing Hong, J. V. Hinrichs, and M. M. Ghoneim. "Caffeine and diazepam: separate and combined effects on mood, memory, and psychomotor performance." Psychopharmacology 87.3: 344-350,1985
  • Referans25 NCA, National Coffee Drinking Trends 2012, National Coffee Association, 2012

  • Referans26 Nehlig, A., Are we dependent upon coffee and caffeine. A review on human and animal data. Neurosci. Biobehav. Rev. 23, 563–576, 1999
  • Referans27 Neil, John F., et al. "Caffeinism complicating hypersomnic depressive episodes." Comprehensive psychiatry 19.4: 377-385, 1978
  • Referans28 O’Keefe, J.H. et al. Effects of habitual coffee consumption on cardiometabolic disease, cardiovascular health, and all-cause mortality. J. Am. Coll. Cardiol. 62, 1043–1051, 2013
  • Referans29 Regestein, Quentin R. "Pathologic sleepiness induced by caffeine." The American journal of medicine 87.5: 586-588, 1989
  • Referans30 Roache, J. D. & Griffiths, R. R. Interactions of diazepam and caffeine: behavioral and subjective dose effects in humans. Pharmacology Biochemistry and Behavior, 26, 801–812, 1987
  • Referans31 Segal, Harold B. The Vienna Coffeehouse Wits: 1890-1938. West Lafayette, Ind.: Purdue University Press, the diets of persons in the United States. J. Am. Diet Assoc. 105, 110–113, 1993
  • Referans32 Spriet LL, MacLean DA, Dyck DJ, et al. Caffeine ingestion and muscle metabolism during prolonged exercise in humans. Am J Physiol; 262 (6 Pt 1): E891-E898, 1992
  • Referans33 Stated, Transcendental Meditation Technique Unless Otherwise. "scientific research on maharishi’s transcendental meditation and tm-sidhi program volumes 1-6. Journal of Physiology 221 (1971): 795-799, 1971
  • Referans34 Terry, W.S., Phifer, B., Caffeine and memory performance on the AVLT. J. Clin. Psychol. 42, 860–863. 1986
  • Referans35 Thelle, Dag S., Egil Arnesen, and Olav H. Førde. "The Tromsö heart study: does coffee raise serum cholesterol?." New England Journal of Medicine 308.24: 1454-1457, 1983
  • Referans36 Van Soeren MH, Graham TE. Effect of caffeine on metabolism, exercise endurance, and catecholamine responses after withdrawal. J Appl Physiol; 85 (1493): 1501, 1998
  • Referans37 Van Soeren MH, Sathasivam P, Spriet LL, et al. Caffeine metabolism and epinephrine responses during exercise in users and nonusers. J Appl Physiol; 75: 805-12 Y. Tank et al., '' Effect of Xanthine Derivatives on Hippocampal Long-term Potentiation,'' Brain Research 522 : 63-68, 1993
  • Referans38 V. E. Mitchell et all., '' Drugs and Places: Effects of Caffeine on Conginitive Performance Pyhchological Reports, 35: 875-83, 1974
  • Referans39 Williams, L. Shawn. "Effects of Low-Level Caffeine Consumption on Long-term Memory Recall of Southern College Students." 1992
  • Referans40 “In the context of learning and memory, it is interesting to note that xanthines, such as theophylline, enhanced long-term potentiation, an elector-pyhsiological model of memory” in guinea pigs. Y. Tank et al., “Effect of Xanthine Derivativeson Hippocampal Long-term Potentiation,” Brain Research 522: 63-68, 1990
  • Referans41 Williams, L. Shawn. "Effects of Low-Level Caffeine Consumption on Long-term Memory Recall of Southern College Students." 1992
There are 41 citations in total.

Details

Subjects Engineering
Journal Section ICAFOF 2017 (International Conference on Agriculture, Forest, Food Sciences and Technologies) Özel Sayısı
Authors

Beyza Özpalas

Emir Ayşe Özer

Publication Date December 21, 2017
Acceptance Date December 18, 2017
Published in Issue Year 2017 Volume:6 ICAFOF Special Issue

Cite

APA Özpalas, B., & Özer, E. A. (2017). Kafeinin İnsan Sağlığı Üzerindeki Etkileri. Nevşehir Bilim Ve Teknoloji Dergisi, 6, 297-305. https://doi.org/10.17100/nevbiltek.331845
AMA Özpalas B, Özer EA. Kafeinin İnsan Sağlığı Üzerindeki Etkileri. Nevşehir Bilim ve Teknoloji Dergisi. December 2017;6:297-305. doi:10.17100/nevbiltek.331845
Chicago Özpalas, Beyza, and Emir Ayşe Özer. “Kafeinin İnsan Sağlığı Üzerindeki Etkileri”. Nevşehir Bilim Ve Teknoloji Dergisi 6, December (December 2017): 297-305. https://doi.org/10.17100/nevbiltek.331845.
EndNote Özpalas B, Özer EA (December 1, 2017) Kafeinin İnsan Sağlığı Üzerindeki Etkileri. Nevşehir Bilim ve Teknoloji Dergisi 6 297–305.
IEEE B. Özpalas and E. A. Özer, “Kafeinin İnsan Sağlığı Üzerindeki Etkileri”, Nevşehir Bilim ve Teknoloji Dergisi, vol. 6, pp. 297–305, 2017, doi: 10.17100/nevbiltek.331845.
ISNAD Özpalas, Beyza - Özer, Emir Ayşe. “Kafeinin İnsan Sağlığı Üzerindeki Etkileri”. Nevşehir Bilim ve Teknoloji Dergisi 6 (December 2017), 297-305. https://doi.org/10.17100/nevbiltek.331845.
JAMA Özpalas B, Özer EA. Kafeinin İnsan Sağlığı Üzerindeki Etkileri. Nevşehir Bilim ve Teknoloji Dergisi. 2017;6:297–305.
MLA Özpalas, Beyza and Emir Ayşe Özer. “Kafeinin İnsan Sağlığı Üzerindeki Etkileri”. Nevşehir Bilim Ve Teknoloji Dergisi, vol. 6, 2017, pp. 297-05, doi:10.17100/nevbiltek.331845.
Vancouver Özpalas B, Özer EA. Kafeinin İnsan Sağlığı Üzerindeki Etkileri. Nevşehir Bilim ve Teknoloji Dergisi. 2017;6:297-305.

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