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A Review: Severe Treatments, Drug and Vaccine studies for Coronavirus Disease (COVID 19)

Year 2022, Issue: 003, 21 - 38, 31.12.2022

Abstract

In 2019, a new type of coronavirus, Severe Acute Respiratory Syndrome Coronavirus (SARS CoV 2) (COVID-19), emerged in Wuhan, China, and this virus spread all over the world and seriously threatened human life. In this review article, the drug and vaccine treatment methods applied against the COVID-19 virus, which seriously threatens the whole world and takes human health to fatal cases, are examined in detail. In some of the applied drug and vaccine treatments and negative effects can be seen as well as positive effects. Due to this reason, the application of some treatment methods has been stopped. Drug and vaccine studies vary from country to country. For this reason, this study aimed to discuss the examples of treatment practices of countries and explain the treatment process.

Thanks

E.E.A, M.B., R.N.E.T., F.S. A.A. collected all review article contents. E.E.A. took care of the writing and layout of the publication.

References

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A Review: Severe Treatments, Drug and Vaccine studies for Coronavirus Disease (COVID 19)

Year 2022, Issue: 003, 21 - 38, 31.12.2022

Abstract

In 2019, a new type of coronavirus, SARS CoV 2, emerged in Wuhan, China, and this virus spread all over the world, seriously threatening human life. In this review article, we have compiled international drug treatments and studies, vaccine treatments and studies, and various studies against COVID 19 disease. Some products are still in the working phase. However, some drugs are very effective against the COVID 19 virus. Besides, the world has started vaccine treatment. Medicine and vaccine studies vary from country to country. For this reason, in this study, examples of treatment practices of countries are given and treatment processes are explained.

References

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  • [2] Rastogi, Y.R., Sharma, A., Nagraik R., (2020), The novel coronavirus 2019-nCoV: Its evolution and transmission into humans causing global COVID-19 pandemic, International Journal of Environmental Science and Technology 17:4381-4388.
  • [3] Zhu, N., Zhang, D., Wang, W., (2020), A Novel Coronavirus from Patients with Pneumonia in China, 2019, New England Journal of Medicine, 382, 727-733.
  • [4] Hodgson SH, Mansatta K., Mallett, G., (2021), What defines an efficacious COVID-19 vaccine? A review of the challenges assessing the clinical efficacy of vaccines .
  • [5] Who, (2020), Coronavirus disease (COVID-19) Global epidemiological situation.
  • [6] Watson, O.J., Barnsley, G., Toor, J., (2022), Global impact of the first year of COVID-19 vaccination: a mathematical modelling study, Lancet, Infect Dis, 22,1293-1302.
  • [7] Tyrrell, D.A.J, Bynoe, M.L., (1966), Cultivation of Viruses from a High Proportion of Patients with Colds, Lancet, 76-7.
  • [8] Pal, M., Berhanu, G., Desalegn, C., Kandi, V. (2020), Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2): An Update. Cureus 12, e00221-18.
  • [9] Qu, G., Li, X., Hu, L., Jiang, G., (2020), An Imperative Need for Research on the Role of Environmental Factors in Transmission of Novel Coronavirus (COVID-19), Environ Sci Technol, 54, 3730-3732.
  • [10] Lai, C.C., Shih, T.P., Ko W.C., (2020), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges, Int J Antimicrob Agents, 55,105924.
  • [11] Zhong, N.S., Zheng, B.J., Li, Y.M., (2003), Epidemiology and cause of severe acute respiratory syndrome (SARS) in Guangdong, People’s Republic of China, in February, 2003, Lancet, 362, 1353-1358.
  • [12] Huang, C., Wang, Y., Li, X., (2020), Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China, The Lancet, 395, 497-506.
  • [13] Zaki, A.M., Van Boheemen, S., Bestebroer, T.M., (2012), Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia, New England Journal of Medicine, 367, 1814-1820.
  • [14] Wu, D., Wu, T., Liu, Q., Yang, Z., (2020), The SARS-CoV-2 outbreak: What we know, International Journal of Infectious Diseases, 94, 44-48.
  • [15] Cui, J., Li, F., Shi. Z.L., (2019), Origin and evolution of pathogenic coronaviruses, Nat Rev Microbiol, 17, 181-192.
  • [16] Gil, C., Ginex, T., Maestro, I., (2020), COVID-19: Drug Targets and Potential Treatments, J Med Chem, 63,12359-12386.
  • [17] Stadler, K., Masignani, V., Eickmann, M., (2003), SARS — beginning to understand a new virus, Nat Rev Microbiol, 1, 209-218.
  • [18] Zhou, Y., Yang, Y., Huang, J., (2019), Advances in MERS-CoV Vaccines and Therapeutics Based on the Receptor-Binding Domain, Viruses, 11,60.
  • [19] Zamaro, A., Kulchitsky, V., (2020), Is COVID-19 a Systemic or Local Pathological Process? SSRN Electronic Journal.
  • [20] Liu, C, von Brunn A, Zhu D., (2020), Cyclophilin A and CD147: novel therapeutic targets for the treatment of COVID-19, Med Drug Discov, 7, 100056.
  • [21] Ulrich, H, Pillat MM., (2020), CD147 as a Target for COVID-19 Treatment: Suggested Effects of Azithromycin and Stem Cell Engagement, Stem Cell Rev Rep, 16, 434-440.
  • [22] Leonardi, A., Rosani U., Brun P., (2020), Ocular Surface Expression of SARS-CoV-2 Receptors. Ocul Immunol Inflamm 28, 735-738.
  • [23] Xu, Z., Shi, L., Wang Y., (2020), Pathological findings of COVID-19 associated with acute respiratory distress syndrome, Lancet Respir, Med 8, 420-422.
  • [24] Chan, J.F.W., Yuan, S., Kok, K.H., (2020), A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster, The Lancet, 395, 514-523.
  • [25] Banerjee, A., Pasea, L., Harris, S., (2020), Estimating excess 1-year mortality associated with the COVID-19 pandemic according to underlying conditions and age: a population-based cohort study, The Lancet, 395, 1715-1725.
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  • [29] Huang, L., Chen, Y., Xiao, J., (2020), Progress in the Research and Development of Anti-COVID-19 Drugs, Front Public Health, 8, 365.
  • [30] Warren, T.K., Jordan, R., Lo, M.K., (2016), Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys, Nature, 531, 381-385.
  • [31] Jean, S.S., Lee, P.I., Hsueh, P.R., (2020), Treatment options for COVID-19: The reality and challenges, Journal of Microbiology, Immunology and Infection 53, 436-443.
  • [32] Sheahan, T.P., Sims, A.C., Graham, R.L., (2017), Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses, Sci., Transl., Med., 9,369.
  • [33] Grein, J., Ohmagari N, Shin D., (2020), Compassionate Use of Remdesivir for Patients with Severe Covid-19, New England Journal of Medicine, 382, 2327-2336.
  • [34] Wang, Y., Fan, G., Salam, A., (2020), Comparative Effectiveness of Combined Favipiravir and Oseltamivir Therapy Versus Oseltamivir Monotherapy in Critically Ill Patients With Influenza Virus Infection, J., Infect., Dis., 221,1688-1698.
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There are 102 citations in total.

Details

Primary Language English
Journal Section Reviews
Authors

Elif Esra Altuner

Muhammed Bekmezci

Rima Nour Elhouda Tiri This is me

Ayşenur Aygün

Fatih Şen

Publication Date December 31, 2022
Submission Date August 15, 2022
Published in Issue Year 2022 Issue: 003

Cite

APA Altuner, E. E., Bekmezci, M., Elhouda Tiri, R. N., Aygün, A., et al. (2022). A Review: Severe Treatments, Drug and Vaccine studies for Coronavirus Disease (COVID 19). Journal of Scientific Reports-C(003), 21-38.
AMA Altuner EE, Bekmezci M, Elhouda Tiri RN, Aygün A, Şen F. A Review: Severe Treatments, Drug and Vaccine studies for Coronavirus Disease (COVID 19). JSR-C. December 2022;(003):21-38.
Chicago Altuner, Elif Esra, Muhammed Bekmezci, Rima Nour Elhouda Tiri, Ayşenur Aygün, and Fatih Şen. “A Review: Severe Treatments, Drug and Vaccine Studies for Coronavirus Disease (COVID 19)”. Journal of Scientific Reports-C, no. 003 (December 2022): 21-38.
EndNote Altuner EE, Bekmezci M, Elhouda Tiri RN, Aygün A, Şen F (December 1, 2022) A Review: Severe Treatments, Drug and Vaccine studies for Coronavirus Disease (COVID 19). Journal of Scientific Reports-C 003 21–38.
IEEE E. E. Altuner, M. Bekmezci, R. N. Elhouda Tiri, A. Aygün, and F. Şen, “A Review: Severe Treatments, Drug and Vaccine studies for Coronavirus Disease (COVID 19)”, JSR-C, no. 003, pp. 21–38, December 2022.
ISNAD Altuner, Elif Esra et al. “A Review: Severe Treatments, Drug and Vaccine Studies for Coronavirus Disease (COVID 19)”. Journal of Scientific Reports-C 003 (December 2022), 21-38.
JAMA Altuner EE, Bekmezci M, Elhouda Tiri RN, Aygün A, Şen F. A Review: Severe Treatments, Drug and Vaccine studies for Coronavirus Disease (COVID 19). JSR-C. 2022;:21–38.
MLA Altuner, Elif Esra et al. “A Review: Severe Treatments, Drug and Vaccine Studies for Coronavirus Disease (COVID 19)”. Journal of Scientific Reports-C, no. 003, 2022, pp. 21-38.
Vancouver Altuner EE, Bekmezci M, Elhouda Tiri RN, Aygün A, Şen F. A Review: Severe Treatments, Drug and Vaccine studies for Coronavirus Disease (COVID 19). JSR-C. 2022(003):21-38.