Fabrication and Characterization of Gelatin/Chitosan Hydrogel Membranes

Thi Sinh Vo; Tran Thi Bich Chau Vo; Truong Sinh Nguyen; Tran Trung Tien

doi:10.18596/jotcsa.942478

Research Article

Fabrication and Characterization of Gelatin/Chitosan Hydrogel Membranes

Year 2021, Volume: 8 Issue: 4, 1045 - 1056, 30.11.2021

Thi Sinh Vo Tran Thi Bich Chau Vo Truong Sinh Nguyen Tran Trung Tien

https://doi.org/10.18596/jotcsa.942478

Cited By: 5

Abstract

The gelatin/chitosan (GEL/CTS, GC) membranes have been fabricated well by a simple in-situ method. The as-prepared GC membranes were characterized by morphological surface (scanning electron microscopy, SEM), chemical (Fourier-transform infrared spectroscopy, FT-IR), crystallinity (X-ray diffraction, XRD), thermal (thermal gravimetric analysis, TGA), mechanical (tensile test), hydrophilic (water contact angle), and swelling properties to elucidate the changes in their chemical structures and morphologies. The morphological structure of the GC membranes was found to be very smooth, non-rough and homogeneous. The FT-IR and XRD studies manifest that the GC membranes have good interaction and compatibility between GEL and CTS in the hydrogel mixture. The prepared GC membranes also obtain better thermal, mechanical and swelling properties comparing to the raw CTS molecule. These results suggest that the nontoxic GC membrane can become a preferred hydrogel membrane in the field of wound dressing or tissue-engineering applications.

Keywords

Chitosan, Gelatin, Swelling, Hydrogel Membrane

Supporting Institution

Project Number

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