Clinical Research
Meme Kanseri Tanısı Almış Kadınlarda Beslenme Durumu, Yaşam Kalitesi ve Akdeniz Diyetine Bağlılığın Değerlendirilmesine İlişkin Bir Araştırma
Abstract
Amaç: Bu araştımanın amacı meme kanseri tanısı almış kadınlarda yaşam kalitesi ve Akdeniz diyetine uyumun araştırılmasıdır.
Gereç ve Yöntem: Bir yıl içerisinde tanı almış 120 meme kanserli kadın araştırmaya katılmıştır. Bazı antropometrik ölçümler alınmıştır. Ayrıca Akdeniz Diyeti Kalite İndeksi (MEDAS) ve Avrupa Kanser Tedavi ve Organizasyon Komitesi Yaşam Kalitesi Ölçeği (EORTC QLQ-C30) kullanılmıştır.
Bulgular: Ortalama yaşları 49.8±10.56 yıl olan 120 meme kanserli katılımcının %42.5’i normal ağırlıktadır. Katılımcıların bel çevreleri ve bel/kalça oranları sırasıyla ortalama 94.6±12.20 cm, 0.87±0.10’dir. Vücut yağ yüzdeleri %36.8±8.61 olarak saptanmıştır. Toplam enerji alımları 1944.9±385.24 kkal ve toplam alınan yağın enerjiden gelen yüzdesi ortalama %35.6±4.81 olarak saptanmıştır. Hastaların ortalama beden kütle indeksi (BKİ) değerleri 29.0±5.80 kg/m2 olup; %40.8’i obezdir. Ortalama MEDAS skoru 7.3±2.65; EORTC QLQ-C30 skoru ise 69.7±11.94’dur. Hastalarda BKI, bel çevresi ile MEDAS skoru arasında negatif; MEDAS skorları ile EORTC skorları arasında pozitif korelasyon saptanmıştır.
Sonuç: Akdeniz diyeti uyumu yüksek olan meme kanseri hastalarının, fiziksel, duygusal ve sosyal yaşam kalitesi daha yüksektir. Bu nedenle meme kanserli hastalarda değiştirilebilir risk faktörlerinin değerlendirilmesi hastalığın prognozu açısından elzemdir.
Keywords
References
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- 5. Kroenke CH, Chen WY, Rosner B, et al. Weight, weight gain, and survival after breast cancer diagnosis. J Clin Oncol. 2005;23(7):1370-1378.
- 6. Rimer BK, Winer EP. Weight gain in women diagnosed with breast cancer. J Am Diet Assoc. 1997;97(5):519-529.
- 7. Saquib N, Flatt SW, Natarajan L, et al. Weight gain and recovery of pre-cancer weight after breast cancer treatments: evidence from the women’s healthy eating and living (WHEL) study. Breast Cancer Res Treat. 2007;105(2):177-186.
- 8. Irwin ML, McTiernan A, Baumgartner RN, et al. Changes in body fat and weight after a breast cancer diagnosis: Influence of demographic, prognostic and lifestyle factors. J Clin Oncol. 2005;23(4):774.
- 9. Brown JK, Byers T, Doyle C, et al. Nutrition and physical activity during and after cancer treatment: an American Cancer Society guide for informed choices. CA Cancer J Clin. 2003;53(5):268-291.
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- 11. Turati F, Carioli G, Bravi F, et al. Mediterranean diet and breast cancer risk. Nutrients. 2018;10(3):326.
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- 16. León-Munoz LM, Guallar-Castillón P, Graciani A, et al. Adherence to the Mediterranean diet pattern has declined in Spanish adults. J Nutr. 2012;142(10):1843-1850.
- 17. Aaronson NK, Ahmedzai S, Bergman B, et al. The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. JNCI. 1993;85(5):365-376.
- 18. Gavric Z, Vukovic-Kostic Z. Assessment of quality of life of women with breast cancer. J Glob Health Sci. 2016;8(9):1.
- 19. Yaw YH, Shariff ZM, Kandiah M, et al. Diet and physical activity in relation to weight change among breast cancer patients. APJCP. 2014;15(1):39-44.
- 20. Raghavendra A, Sinha AK, Valle-Goffin J, et al. Determinants of weight gain during adjuvant endocrine therapy and association of such weight gain with recurrence in long-term breast cancer survivors. Clin Breast Cancer. 2018;18(1):e7-e13.
- 21. Irwin ML, Crumley D, McTiernan A, et al. Physical activity levels before and after a diagnosis of breast carcinoma: the Health, Eating, Activity, and Lifestyle (HEAL) study. Cancer.2003;97(7):1746-1757.
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- 29. George SM, Bernstein L, Smith AW, et al. Central adiposity after breast cancer diagnosis is related to mortality in the Health, Eating, Activity, and Lifestyle study. Breast Cancer Res Treat. 2014;146(3):647-655.
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- 32. Gallagher EJ, LeRoith D. The proliferating role of insulin and insulin-like growth factors in cancer. Trends Endocrinol Metab. 2010;21(10):610-618.
- 33. Howard BV, Van Horn L, Hsia J, et al. Low-fat dietary pattern and risk of cardiovascular disease: the Women's Health Initiative Randomized Controlled Dietary Modification Trial. JAMA. 2006;295(6):655-666.
- 34. Turner LB. A meta‐analysis of fat intake, reproduction, and breast cancer risk: An evolutionary perspective. Am J Hum Biol. 2011;23(5):601-608.
- 35. Aygin D, Cengiz H. Life quality of patients who underwent breast reconstruction after prophylactic mastectomy: systematic review. Breast Cancer. 2018;25(5):497-505.
- 36. Lis CG, Gupta D, Lammersfeld CA, et al. Role of nutritional status in predicting quality of life outcomes in cancer–a systematic review of the epidemiological literature. Nutr J. 2012;11(1):1-18.
- 37. Montagnese C, Porciello G, Vitale S, et al. Quality of life in women diagnosed with breast cancer after a 12-month treatment of lifestyle modifications. Nutrients. 2020;13(1):136.
- 38. Lohmann AE, Ennis M, Taylor SK, et al. Metabolic factors, anthropometric measures, diet, and physical activity in long-term breast cancer survivors: change from diagnosis and comparison to non-breast cancer controls. Breast Cancer Res Treat. 2017;164:451-460.
- 39. Harborg S, Feldt M, Cronin-Fenton D, et al. Obesity and breast cancer prognosis: pre-diagnostic anthropometric measures in relation to patient, tumor, and treatment characteristics. Cancer Metab. 2023;11(1):1-11.
- 40. Chen X, Lu W, Zheng W, et al. Obesity and weight change in relation to breast cancer survival. Breast Cancer Res Treat. 2010;122:823-833.
- 41. Di Maso M, Maso LD, Augustin LS, et al. Adherence to the Mediterranean diet and mortality after breast cancer. Nutrients. 2020;12(12):3649.
- 42. James F, Wootton S, Jackson A, et al. Obesity in breast cancer–what is the risk factor? Eur J Cancer 2015; 51; 705-720.
- 43. Ataeinia B, Saeedi Moghaddam S, Shabani M, et al. National and subnational incidence, mortality, and years of life lost due to breast cancer in Iran: trends and age-period-cohort analysis since 1990. Front Oncol. 2021; 11: 561376.
- 44. Brennan SF, Woodside JV, Lunny PM, et al. Dietary fat and breast cancer mortality: A systematic review and meta-analysis. Crit. Rev. Food Sci. Nutr. 2017; 57: 1999-2008.
An Investigation into the Assessment of Nutritional Status, Quality of Life, and Adherence to the Mediterranean Diet among Women Affected by Breast Cancer
Abstract
Aim: The aim of this study is to assess the quality of life and adherence to the Mediterranean diet (MD) among female breast cancer patients.
Material and Method: The study included a cohort of 120 women who received a breast cancer diagnosis within the last year. Anthropometric measurements were conducted, and body composition analysis was carried out to determine body fat percentage. The Mediterranean Diet Adherence Scale (MEDAS) and the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30) were employed for data collection.
Results: A total of 120 breast cancer patients, with an average age of 49.8±10.56 years, were enrolled in the study. Among these participants, 42.5% were categorized as having a normal weight. The mean waist circumference and waist/hip ratio were 94.6±12.20 cm and 0.87±0.10, respectively. Body fat percentages were determined to be 36.8±8.61%. The average total energy intake was 1944.9±385.24 kcal, with the percentage of total fat intake from energy averaging at 35.6±4.81%. Patients had a mean body mass index (BMI) of 29.0±5.80 kg/m², with 40.8% of them classified as obese. The mean MEDAS score was 7.3±2.65, and the EORTC QLQ-C30 score averaged at 69.7±11.94. There is a negative correlation was found between BMI, waist circumference and MEDAS score; A positive correlation was found between MEDAS scores and EORTC scores.
Conclusion: Breast cancer patients with high compliance with the Mediterranean diet have a higher quality of physical, emotional and social life. Therefore, evaluation of modifiable risk factors in breast cancer patients is essential for the prognosis of the disease.
References
- 1. World Health Organization International Agency for Research on Cancer Turkey source: globocan 2020. International Agency for Research on Cancer [cited 28 April 2023]. Available from : https://gco.iarc.fr/today/data/factsheets/populations/792-turkey-fact-sheets.pdf
- 2. Turati F, Dalmartello M, Bravi F, et al. Adherence to the world cancer research fund/american institute for cancer research recommendations and the risk of breast cancer. Nutrients. 2020;12(3):607.
- 3. Van den Berg MMGA, Winkel RM, de Kruif J ThCM et al. Weight change during chemotherapy in breast cancer patients: a meta-analysis. BMC cancer vol. 17,1 259. 12 Apr. 2017.
- 4. Goodwin PJ, Ennis M, Pritchard KI, et al. Adjuvant treatment and onset of menopause predict weight gain after breast cancer diagnosis. J Clin Oncol. 1999;17(1):120-120.
- 5. Kroenke CH, Chen WY, Rosner B, et al. Weight, weight gain, and survival after breast cancer diagnosis. J Clin Oncol. 2005;23(7):1370-1378.
- 6. Rimer BK, Winer EP. Weight gain in women diagnosed with breast cancer. J Am Diet Assoc. 1997;97(5):519-529.
- 7. Saquib N, Flatt SW, Natarajan L, et al. Weight gain and recovery of pre-cancer weight after breast cancer treatments: evidence from the women’s healthy eating and living (WHEL) study. Breast Cancer Res Treat. 2007;105(2):177-186.
- 8. Irwin ML, McTiernan A, Baumgartner RN, et al. Changes in body fat and weight after a breast cancer diagnosis: Influence of demographic, prognostic and lifestyle factors. J Clin Oncol. 2005;23(4):774.
- 9. Brown JK, Byers T, Doyle C, et al. Nutrition and physical activity during and after cancer treatment: an American Cancer Society guide for informed choices. CA Cancer J Clin. 2003;53(5):268-291.
- 10. Laudisio D, Barrea L, Muscogiuri G, et al. Breast cancer prevention in premenopausal women: Role of the Mediterranean diet and its components. Nutri Res Rev. 2020;33(1):19-32.
- 11. Turati F, Carioli G, Bravi F, et al. Mediterranean diet and breast cancer risk. Nutrients. 2018;10(3):326.
- 12. Kwan ML, Weltzien E, Kushi LH, et al. Dietary patterns and breast cancer recurrence and survival among women with early-stage breast cancer. J Clin Oncol. 2009;27(6):919.
- 13. Waist circumference and waist–hip ratio: report of a WHO expert consultation [cited 02 April 2022]. Available from : http://appswhoint/iris/bitstream/handle/10665/44583/9789241501491_eng;jsessionid=EDD70A9971BF6AD4DC0AA8019D5D1B31?sequence=1.
- 14. World Health Organization. Body mass index [cited 15 july 2023]. Available from : https://www.euro.who.int/en/health-topics/disease-prevention/nutrition/ahealthy-lifestyle/body-mass-index-bmi.
- 15. Dehne LI, Klemm C, Henseler G, et al. The German food code and nutrient data base (BLS II. 2). Eur J Epidemiol. 1999;15(4):355-358.
- 16. León-Munoz LM, Guallar-Castillón P, Graciani A, et al. Adherence to the Mediterranean diet pattern has declined in Spanish adults. J Nutr. 2012;142(10):1843-1850.
- 17. Aaronson NK, Ahmedzai S, Bergman B, et al. The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. JNCI. 1993;85(5):365-376.
- 18. Gavric Z, Vukovic-Kostic Z. Assessment of quality of life of women with breast cancer. J Glob Health Sci. 2016;8(9):1.
- 19. Yaw YH, Shariff ZM, Kandiah M, et al. Diet and physical activity in relation to weight change among breast cancer patients. APJCP. 2014;15(1):39-44.
- 20. Raghavendra A, Sinha AK, Valle-Goffin J, et al. Determinants of weight gain during adjuvant endocrine therapy and association of such weight gain with recurrence in long-term breast cancer survivors. Clin Breast Cancer. 2018;18(1):e7-e13.
- 21. Irwin ML, Crumley D, McTiernan A, et al. Physical activity levels before and after a diagnosis of breast carcinoma: the Health, Eating, Activity, and Lifestyle (HEAL) study. Cancer.2003;97(7):1746-1757.
- 22. Öztürk Z, Özerson ZK, İpek KD. Meme kanseri tanısı konulmuş yetişkin kadınların beslenme alışkanlıklarının değerlendirilmesi. Haliç Üniv Sağlık Bil Der. 2018;1(1):1-13.
- 23. Davis J, Jimenez C, Clinton C, et al. Abstract C064: Hormone-related risk factors and breast cancer subtype in African American women. Cancer Epidemiology, Biomarkers & Prevention 2020; 29: C064-C064.
- 24. Boltong A, Aranda S, Keast R, et al. A prospective cohort study of the effects of adjuvant breast cancer chemotherapy on taste function, food liking, appetite and associated nutritional outcomes. PLoS One. 2014;9(7):e103512.
- 25. Chan DSM, Viera R, Aune D, et al. Body mass index and survival in women with breast cancer-systematic literature review and meta-analysis of 82 follow-up studies. Ann Oncol. 2014 Oct; (25)10:1901-1914
- 26. Ronco AL, De Stéfani E. Nutritional epidemiology of breast cancer: Springer Science & Business Media 2011.
- 27. Lee C, Raffaghello L, Brandhorst S, et al. Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy. Sci Transl Med. 2012;4(124):124ra127-124ra127.
- 28. Lahmann PH, Hoffmann K, Allen N, et al. Body size and breast cancer risk: findings from the European Prospective Investigation into Cancer And Nutrition (EPIC). Int J Cancer. 2004;111(5):762-771.
- 29. George SM, Bernstein L, Smith AW, et al. Central adiposity after breast cancer diagnosis is related to mortality in the Health, Eating, Activity, and Lifestyle study. Breast Cancer Res Treat. 2014;146(3):647-655.
- 30. Iyengar NM, Arthur R, Manson JE, et al. Association of body fat and risk of breast cancer in postmenopausal women with normal body mass index: a secondary analysis of a randomized clinical trial and observational study. JAMA Oncol. 2019;5(2):155-163.
- 31. Friedenreich C. Review of anthropometric factors and breast cancer risk. Eur J Cancer Prev. 2001:15-32.
- 32. Gallagher EJ, LeRoith D. The proliferating role of insulin and insulin-like growth factors in cancer. Trends Endocrinol Metab. 2010;21(10):610-618.
- 33. Howard BV, Van Horn L, Hsia J, et al. Low-fat dietary pattern and risk of cardiovascular disease: the Women's Health Initiative Randomized Controlled Dietary Modification Trial. JAMA. 2006;295(6):655-666.
- 34. Turner LB. A meta‐analysis of fat intake, reproduction, and breast cancer risk: An evolutionary perspective. Am J Hum Biol. 2011;23(5):601-608.
- 35. Aygin D, Cengiz H. Life quality of patients who underwent breast reconstruction after prophylactic mastectomy: systematic review. Breast Cancer. 2018;25(5):497-505.
- 36. Lis CG, Gupta D, Lammersfeld CA, et al. Role of nutritional status in predicting quality of life outcomes in cancer–a systematic review of the epidemiological literature. Nutr J. 2012;11(1):1-18.
- 37. Montagnese C, Porciello G, Vitale S, et al. Quality of life in women diagnosed with breast cancer after a 12-month treatment of lifestyle modifications. Nutrients. 2020;13(1):136.
- 38. Lohmann AE, Ennis M, Taylor SK, et al. Metabolic factors, anthropometric measures, diet, and physical activity in long-term breast cancer survivors: change from diagnosis and comparison to non-breast cancer controls. Breast Cancer Res Treat. 2017;164:451-460.
- 39. Harborg S, Feldt M, Cronin-Fenton D, et al. Obesity and breast cancer prognosis: pre-diagnostic anthropometric measures in relation to patient, tumor, and treatment characteristics. Cancer Metab. 2023;11(1):1-11.
- 40. Chen X, Lu W, Zheng W, et al. Obesity and weight change in relation to breast cancer survival. Breast Cancer Res Treat. 2010;122:823-833.
- 41. Di Maso M, Maso LD, Augustin LS, et al. Adherence to the Mediterranean diet and mortality after breast cancer. Nutrients. 2020;12(12):3649.
- 42. James F, Wootton S, Jackson A, et al. Obesity in breast cancer–what is the risk factor? Eur J Cancer 2015; 51; 705-720.
- 43. Ataeinia B, Saeedi Moghaddam S, Shabani M, et al. National and subnational incidence, mortality, and years of life lost due to breast cancer in Iran: trends and age-period-cohort analysis since 1990. Front Oncol. 2021; 11: 561376.
- 44. Brennan SF, Woodside JV, Lunny PM, et al. Dietary fat and breast cancer mortality: A systematic review and meta-analysis. Crit. Rev. Food Sci. Nutr. 2017; 57: 1999-2008.
There are 44 citations in total.
Details
| Primary Language | English |
|---|---|
| Subjects | Clinical Oncology, Clinical Sciences (Other) |
| Journal Section | Original Research |
| Authors | |
| Publication Date | September 30, 2023 |
| Acceptance Date | September 23, 2023 |
| Published in Issue | Year 2023 Volume: 13 Issue: 5 |
