Review
BibTex RIS Cite

Investigating medicinal plants for antimicrobial benefits in a changing climate

Year 2024, Volume: 11 Issue: 2, 364 - 377

Ali Yetgin

https://doi.org/10.21448/ijsm.1279531

Abstract

As the world's climate changes, there is growing concern about how it is affecting human health, including the rise of antimicrobial resistance. Medicinal plants have been used for centuries and their antimicrobial properties have been recognized by many cultures. This article focuses on exploring the potential of medicinal plants for antimicrobial activity in the face of climate change challenges. The article discusses the challenges and opportunities associated with using medicinal plants as a source of new antimicrobial agents, including issues related to the changes in plant chemistry caused by climate change, and the need for sustainable and ethical sourcing practices. The article also examines the importance of traditional knowledge and cultural practices in the development and conservation of medicinal plants. Finally, the article highlights the importance of interdisciplinary research and collaboration in harnessing the potential of medicinal plants for combating antimicrobial resistance in the context of a changing climate.

Keywords

Medicinal plants Antimicrobial activity Climate change Sustainability Phytochemicals

Project Number

Yok

References

  • Alissa, E.M. (2014). Medicinal herbs and therapeutic drugs interactions. Therapeutic Drug Monitoring, 36(4), 413-422.
  • Alvin, A., Miller, K.I., & Neilan, B.A. (2014). Exploring the potential of endophytes from medicinal plants as sources of antimycobacterial compounds. Microbiological Research, 169(7-8), 483-495.
  • Anand, U., Jacobo-Herrera, N., Altemimi, A., & Lakhssassi, N. (2019). A comprehensive review on medicinal plants as antimicrobial therapeutics: potential avenues of biocompatible drug discovery. Metabolites, 9(11), 258.
  • Bahmani, M., Golshahi, H., Saki, K., Rafieian-Kopaei, M., Delfan, B., & Mohammadi, T. (2014). Medicinal plants and secondary metabolites for diabetes mellitus control. Asian Pacific Journal of Tropical Disease, 4, S687-S692.
  • Borges, C.V., Minatel, I.O., Gomez-Gomez, H.A., & Lima, G.P.P. (2017). Medicinal plants: Influence of environmental factors on the content of secondary metabolites. Medicinal Plants and Environmental Challenges, 259-277.
  • Brusotti, G., Cesari, I., Dentamaro, A., Caccialanza, G., & Massolini, G. (2014). Isolation and characterization of bioactive compounds from plant resources: The role of analysis in the ethnopharmacological approach. Journal of Pharmaceutical and Biomedical Analysis, 87, 218-228.
  • Chandra, S., Chandola, V., Sultan, Z., Singh, C.P., Purohit, V.K., Nautiyal, B.P., & Nautiyal, M.C. (2022). Climate change adversely affects the medicinal value of Aconitum species in Alpine region of Indian Himalaya. Industrial Crops and Products, 186, 115277.
  • Chao, S.C., Young, D.G., & Oberg, C.J. (2000). Screening for inhibitory activity of essential oils on selected bacteria, fungi and viruses. Journal of Essential Oil Research, 12(5), 639-649.
  • Chen, S.L., Yu, H., Luo, H.M., Wu, Q., Li, C.F., & Steinmetz, A. (2016). Conservation and sustainable use of medicinal plants: problems, progress, and prospects. Chinese Medicine, 11, 1-10.
  • Croteau, R., Kutchan, T.M., & Lewis, N.G. (2000). Natural products (secondary metabolites). Biochemistry and Molecular Biology of Plants, 24, 1250-1319.
  • Das, M., Jain, V., & Malhotra, S. (2016). Impact of climate change on medicinal and aromatic plants. Indian J Agric Sci, 86(11), 1375-1382.
  • Dumas, N.G.E., Anderson, N.T.Y., Godswill, N.N., Thiruvengadam, M., Ana‐Maria, G., Ramona, P., ... & Emmanuel, Y. (2021). Secondary metabolite contents and antimicrobial activity of leaf extracts reveal genetic variability of Vernonia amygdalina and Vernonia calvoana morphotypes. Biotechnology and Applied Biochemistry, 68(4), 938-947.
  • Etebu, E., & Arikekpar, I. (2016). Antibiotics: Classification and mechanisms of action with emphasis on molecular perspectives. Int. J. Appl. Microbiol. Biotechnol. Res, 4(2016), 90-101.
  • Farzaneh, V., & Carvalho, I.S. (2015). A review of the health benefit potentials of herbal plant infusions and their mechanism of actions. Industrial Crops and Products, 65, 247-258.
  • Figueiredo, A.C., Barroso, J.G., Pedro, L.G., & Scheffer, J.J. (2008). Factors affecting secondary metabolite production in plants: volatile components and essential oils. Flavour and Fragrance Journal, 23(4), 213-226.
  • Henry, A., Doucette, W., Norton, J., & Bugbee, B. (2007). Changes in crested wheatgrass root exudation caused by flood, drought, and nutrient stress. Journal of Environmental Quality, 36(3), 904-912.
  • Huang, Z., Pan, X., Zhou, J., Leung, W.T., Li, C., & Wang, L. (2019). Chinese herbal medicine for acute upper respiratory tract infections and reproductive safety: a systematic review. BioScience Trends, 13(2), 117-129.
  • Jain, C., Khatana, S., & Vijayvergia, R. (2019). Bioactivity of secondary metabolites of various plants: a review. Int. J. Pharm. Sci. Res, 10(2), 494-504.
  • Jan, R., Asaf, S., Numan, M., & Kim, K.M. (2021). Plant secondary metabolite biosynthesis and transcriptional regulation in response to biotic and abiotic stress conditions. Agronomy, 11(5), 968.
  • Joshi, B., Panda, S.K., Jouneghani, R.S., Liu, M., Parajuli, N., Leyssen, P., ... & Luyten, W. (2020). Antibacterial, antifungal, antiviral, and anthelmintic activities of medicinal plants of Nepal selected based on ethnobotanical evidence. Evidence-Based Complementary and Alternative Medicine, 2020.
  • Kudo, G., & Hirao, A.S. (2006). Habitat-specific responses in the flowering phenology and seed set of alpine plants to climate variation: implications for global-change impacts. Population Ecology, 48, 49-58.
  • Kukula-Koch, W., & Widelski, J. (2017). Alkaloids. Pharmacognosy.
  • Kumar, V., & Sharma, Y. (2018). Effects of environment on the chemical constituents and biological characteristics of some medicinal plants. In Phytochemistry (pp. 279-292). Apple Academic Press.
  • Lafferty, K.D. (2009). The ecology of climate change and infectious diseases. Ecology, 90(4), 888-900.
  • Ludwiczuk, A., Skalicka-Woźniak, K., & Georgiev, M. I. (2017). Terpenoids. In Pharmacognosy (pp. 233-266). Academic Press.
  • Meshnick, S.R., & Dobson, M.J. (2001) The history of antimalarial drugs. In: P.J. Rosenthal, (ed). Antimalarial chemotherapy: Mechanisms of action, resistance, and new directions in drug discovery, pp. 15 – 25. Human Press Inc.
  • Mulat, M., Pandita, A., & Khan, F. (2019). Medicinal plant compounds for combating the multi-drug resistant pathogenic bacteria: a review. Current Pharmaceutical Biotechnology, 20(3), 183-196.
  • Nascimento, G.G., Locatelli, J., Freitas, P.C., & Silva, G.L. (2000). Antibacterial activity of plant extracts and phytochemicals on antibiotic-resistant bacteria. Brazilian Journal of Microbiology, 31, 247-256.
  • Ncube, B., Finnie, J.F., & Van Staden, J. (2012). Quality from the field: The impact of environmental factors as quality determinants in medicinal plants. South African Journal of Botany, 82, 11-20.
  • Pandey, A.K., & Savita, R. (2017). Harvesting and post-harvest processing of medicinal plants: Problems and prospects. The Pharma Innovation Journal, 6(12), 229-235.
  • Patz, J.A., Githeko, A.K., McCarty, J.P., Hussein, S., Confalonieri, U., & De Wet, N. (2003). Climate change and infectious diseases. Climate Change and Human Health: Risks and Responses, 2, 103-132.
  • Payyappallimana, U. (2010). Role of traditional medicine in primary health care. Yokohama Journal of Social Sciences, 14(6), 57-75.
  • Prinsloo, G., & Nogemane, N. (2018). The effects of season and water availability on chemical composition, secondary metabolites and biological activity in plants. Phytochemistry Reviews, 17(4), 889-902.
  • Rosenzweig, C., Iglesius, A., Yang, X.B., Epstein, P.R., & Chivian, E. (2001). Climate change and extreme weather events-Implications for food production, plant diseases, and pests.
  • Rupani, R., & Chavez, A. (2018). Medicinal plants with traditional use: Ethnobotany in the Indian subcontinent. Clinics in Dermatology, 36(3), 306-309.
  • Sen, T., & Samanta, S.K. (2015). Medicinal plants, human health and biodiversity: a broad review. Biotechnological Applications of Biodiversity, 59-110.
  • Serwecińska, L. (2020). Antimicrobials and antibiotic-resistant bacteria: a risk to the environment and to public health. Water, 12(12), 3313.
  • Seth, S.D., & Sharma, B. (2004). Medicinal plants in India. Indian Journal of Medical Research, 120(1), 9.
  • Shakya, A.K. (2016). Medicinal plants: Future source of new drugs. International Journal of Herbal Medicine, 4(4), 59-64.
  • Sharma, M., Thakur, R., Sharma, M., Sharma, A.K., & Sharma, A.K. (2020). Changing scenario of medicinal plants diversity in relation to climate changes: A review. Plant Archives, 20(2), 4389-4400.
  • Sieniawska, E., & Baj, T. (2017). Tannins. In Pharmacognosy (pp. 199-232). Academic Press.
  • Srinivasan, D., Nathan, S., Suresh, T., & Perumalsamy, P.L. (2001). Antimicrobial activity of certain Indian medicinal plants used in folkloric medicine. Journal of Ethnopharmacology, 74(3), 217-220.
  • Sultana, B., Anwar, F., & Ashraf, M. (2009). Effect of extraction solvent/technique on the antioxidant activity of selected medicinal plant extracts. Molecules, 14(6), 2167-2180.
  • Talbert, R., & Wall, R. (2012). Toxicity of essential and non-essential oils against the chewing louse, Bovicola (Werneckiella) ocellatus. Research in Veterinary Science, 93(2), 831-835.
  • Tomasz, A. (1994). Multiple-Antibiotic-Resistant Pathogenic Bacteria--A Report on the Rockefeller University Workshop. New England journal of medicine, 330(17), 1247-1251.
  • Vaou, N., Stavropoulou, E., Voidarou, C., Tsigalou, C., & Bezirtzoglou, E. (2021). Towards advances in medicinal plant antimicrobial activity: A review study on challenges and future perspectives. Microorganisms, 9(10), 2041.
  • World Health Organization. (2021). Global antimicrobial resistance and use surveillance system (GLASS) report: 2021.

Investigating medicinal plants for antimicrobial benefits in a changing climate

Year 2024, Volume: 11 Issue: 2, 364 - 377

Ali Yetgin

https://doi.org/10.21448/ijsm.1279531

Abstract

As the world's climate changes, there is growing concern about how it is affecting human health, including the rise of antimicrobial resistance. Medicinal plants have been used for centuries and their antimicrobial properties have been recognized by many cultures. This article focuses on exploring the potential of medicinal plants for antimicrobial activity in the face of climate change challenges. The article discusses the challenges and opportunities associated with using medicinal plants as a source of new antimicrobial agents, including issues related to the changes in plant chemistry caused by climate change, and the need for sustainable and ethical sourcing practices. The article also examines the importance of traditional knowledge and cultural practices in the development and conservation of medicinal plants. Finally, the article highlights the importance of interdisciplinary research and collaboration in harnessing the potential of medicinal plants for combating antimicrobial resistance in the context of a changing climate.

Keywords

Medicinal plants Antimicrobial activity Climate change Sustainability Phytochemicals

Supporting Institution

Yok

Project Number

Yok

Thanks

Yok

References

  • Alissa, E.M. (2014). Medicinal herbs and therapeutic drugs interactions. Therapeutic Drug Monitoring, 36(4), 413-422.
  • Alvin, A., Miller, K.I., & Neilan, B.A. (2014). Exploring the potential of endophytes from medicinal plants as sources of antimycobacterial compounds. Microbiological Research, 169(7-8), 483-495.
  • Anand, U., Jacobo-Herrera, N., Altemimi, A., & Lakhssassi, N. (2019). A comprehensive review on medicinal plants as antimicrobial therapeutics: potential avenues of biocompatible drug discovery. Metabolites, 9(11), 258.
  • Bahmani, M., Golshahi, H., Saki, K., Rafieian-Kopaei, M., Delfan, B., & Mohammadi, T. (2014). Medicinal plants and secondary metabolites for diabetes mellitus control. Asian Pacific Journal of Tropical Disease, 4, S687-S692.
  • Borges, C.V., Minatel, I.O., Gomez-Gomez, H.A., & Lima, G.P.P. (2017). Medicinal plants: Influence of environmental factors on the content of secondary metabolites. Medicinal Plants and Environmental Challenges, 259-277.
  • Brusotti, G., Cesari, I., Dentamaro, A., Caccialanza, G., & Massolini, G. (2014). Isolation and characterization of bioactive compounds from plant resources: The role of analysis in the ethnopharmacological approach. Journal of Pharmaceutical and Biomedical Analysis, 87, 218-228.
  • Chandra, S., Chandola, V., Sultan, Z., Singh, C.P., Purohit, V.K., Nautiyal, B.P., & Nautiyal, M.C. (2022). Climate change adversely affects the medicinal value of Aconitum species in Alpine region of Indian Himalaya. Industrial Crops and Products, 186, 115277.
  • Chao, S.C., Young, D.G., & Oberg, C.J. (2000). Screening for inhibitory activity of essential oils on selected bacteria, fungi and viruses. Journal of Essential Oil Research, 12(5), 639-649.
  • Chen, S.L., Yu, H., Luo, H.M., Wu, Q., Li, C.F., & Steinmetz, A. (2016). Conservation and sustainable use of medicinal plants: problems, progress, and prospects. Chinese Medicine, 11, 1-10.
  • Croteau, R., Kutchan, T.M., & Lewis, N.G. (2000). Natural products (secondary metabolites). Biochemistry and Molecular Biology of Plants, 24, 1250-1319.
  • Das, M., Jain, V., & Malhotra, S. (2016). Impact of climate change on medicinal and aromatic plants. Indian J Agric Sci, 86(11), 1375-1382.
  • Dumas, N.G.E., Anderson, N.T.Y., Godswill, N.N., Thiruvengadam, M., Ana‐Maria, G., Ramona, P., ... & Emmanuel, Y. (2021). Secondary metabolite contents and antimicrobial activity of leaf extracts reveal genetic variability of Vernonia amygdalina and Vernonia calvoana morphotypes. Biotechnology and Applied Biochemistry, 68(4), 938-947.
  • Etebu, E., & Arikekpar, I. (2016). Antibiotics: Classification and mechanisms of action with emphasis on molecular perspectives. Int. J. Appl. Microbiol. Biotechnol. Res, 4(2016), 90-101.
  • Farzaneh, V., & Carvalho, I.S. (2015). A review of the health benefit potentials of herbal plant infusions and their mechanism of actions. Industrial Crops and Products, 65, 247-258.
  • Figueiredo, A.C., Barroso, J.G., Pedro, L.G., & Scheffer, J.J. (2008). Factors affecting secondary metabolite production in plants: volatile components and essential oils. Flavour and Fragrance Journal, 23(4), 213-226.
  • Henry, A., Doucette, W., Norton, J., & Bugbee, B. (2007). Changes in crested wheatgrass root exudation caused by flood, drought, and nutrient stress. Journal of Environmental Quality, 36(3), 904-912.
  • Huang, Z., Pan, X., Zhou, J., Leung, W.T., Li, C., & Wang, L. (2019). Chinese herbal medicine for acute upper respiratory tract infections and reproductive safety: a systematic review. BioScience Trends, 13(2), 117-129.
  • Jain, C., Khatana, S., & Vijayvergia, R. (2019). Bioactivity of secondary metabolites of various plants: a review. Int. J. Pharm. Sci. Res, 10(2), 494-504.
  • Jan, R., Asaf, S., Numan, M., & Kim, K.M. (2021). Plant secondary metabolite biosynthesis and transcriptional regulation in response to biotic and abiotic stress conditions. Agronomy, 11(5), 968.
  • Joshi, B., Panda, S.K., Jouneghani, R.S., Liu, M., Parajuli, N., Leyssen, P., ... & Luyten, W. (2020). Antibacterial, antifungal, antiviral, and anthelmintic activities of medicinal plants of Nepal selected based on ethnobotanical evidence. Evidence-Based Complementary and Alternative Medicine, 2020.
  • Kudo, G., & Hirao, A.S. (2006). Habitat-specific responses in the flowering phenology and seed set of alpine plants to climate variation: implications for global-change impacts. Population Ecology, 48, 49-58.
  • Kukula-Koch, W., & Widelski, J. (2017). Alkaloids. Pharmacognosy.
  • Kumar, V., & Sharma, Y. (2018). Effects of environment on the chemical constituents and biological characteristics of some medicinal plants. In Phytochemistry (pp. 279-292). Apple Academic Press.
  • Lafferty, K.D. (2009). The ecology of climate change and infectious diseases. Ecology, 90(4), 888-900.
  • Ludwiczuk, A., Skalicka-Woźniak, K., & Georgiev, M. I. (2017). Terpenoids. In Pharmacognosy (pp. 233-266). Academic Press.
  • Meshnick, S.R., & Dobson, M.J. (2001) The history of antimalarial drugs. In: P.J. Rosenthal, (ed). Antimalarial chemotherapy: Mechanisms of action, resistance, and new directions in drug discovery, pp. 15 – 25. Human Press Inc.
  • Mulat, M., Pandita, A., & Khan, F. (2019). Medicinal plant compounds for combating the multi-drug resistant pathogenic bacteria: a review. Current Pharmaceutical Biotechnology, 20(3), 183-196.
  • Nascimento, G.G., Locatelli, J., Freitas, P.C., & Silva, G.L. (2000). Antibacterial activity of plant extracts and phytochemicals on antibiotic-resistant bacteria. Brazilian Journal of Microbiology, 31, 247-256.
  • Ncube, B., Finnie, J.F., & Van Staden, J. (2012). Quality from the field: The impact of environmental factors as quality determinants in medicinal plants. South African Journal of Botany, 82, 11-20.
  • Pandey, A.K., & Savita, R. (2017). Harvesting and post-harvest processing of medicinal plants: Problems and prospects. The Pharma Innovation Journal, 6(12), 229-235.
  • Patz, J.A., Githeko, A.K., McCarty, J.P., Hussein, S., Confalonieri, U., & De Wet, N. (2003). Climate change and infectious diseases. Climate Change and Human Health: Risks and Responses, 2, 103-132.
  • Payyappallimana, U. (2010). Role of traditional medicine in primary health care. Yokohama Journal of Social Sciences, 14(6), 57-75.
  • Prinsloo, G., & Nogemane, N. (2018). The effects of season and water availability on chemical composition, secondary metabolites and biological activity in plants. Phytochemistry Reviews, 17(4), 889-902.
  • Rosenzweig, C., Iglesius, A., Yang, X.B., Epstein, P.R., & Chivian, E. (2001). Climate change and extreme weather events-Implications for food production, plant diseases, and pests.
  • Rupani, R., & Chavez, A. (2018). Medicinal plants with traditional use: Ethnobotany in the Indian subcontinent. Clinics in Dermatology, 36(3), 306-309.
  • Sen, T., & Samanta, S.K. (2015). Medicinal plants, human health and biodiversity: a broad review. Biotechnological Applications of Biodiversity, 59-110.
  • Serwecińska, L. (2020). Antimicrobials and antibiotic-resistant bacteria: a risk to the environment and to public health. Water, 12(12), 3313.
  • Seth, S.D., & Sharma, B. (2004). Medicinal plants in India. Indian Journal of Medical Research, 120(1), 9.
  • Shakya, A.K. (2016). Medicinal plants: Future source of new drugs. International Journal of Herbal Medicine, 4(4), 59-64.
  • Sharma, M., Thakur, R., Sharma, M., Sharma, A.K., & Sharma, A.K. (2020). Changing scenario of medicinal plants diversity in relation to climate changes: A review. Plant Archives, 20(2), 4389-4400.
  • Sieniawska, E., & Baj, T. (2017). Tannins. In Pharmacognosy (pp. 199-232). Academic Press.
  • Srinivasan, D., Nathan, S., Suresh, T., & Perumalsamy, P.L. (2001). Antimicrobial activity of certain Indian medicinal plants used in folkloric medicine. Journal of Ethnopharmacology, 74(3), 217-220.
  • Sultana, B., Anwar, F., & Ashraf, M. (2009). Effect of extraction solvent/technique on the antioxidant activity of selected medicinal plant extracts. Molecules, 14(6), 2167-2180.
  • Talbert, R., & Wall, R. (2012). Toxicity of essential and non-essential oils against the chewing louse, Bovicola (Werneckiella) ocellatus. Research in Veterinary Science, 93(2), 831-835.
  • Tomasz, A. (1994). Multiple-Antibiotic-Resistant Pathogenic Bacteria--A Report on the Rockefeller University Workshop. New England journal of medicine, 330(17), 1247-1251.
  • Vaou, N., Stavropoulou, E., Voidarou, C., Tsigalou, C., & Bezirtzoglou, E. (2021). Towards advances in medicinal plant antimicrobial activity: A review study on challenges and future perspectives. Microorganisms, 9(10), 2041.
  • World Health Organization. (2021). Global antimicrobial resistance and use surveillance system (GLASS) report: 2021.
There are 47 citations in total.

Details

Primary Language English
Subjects Structural Biology
Journal Section Articles
Authors

Ali Yetgin 0000-0001-7683-8836

Project Number Yok
Early Pub Date April 22, 2024
Publication Date
Submission Date April 8, 2023
Published in Issue Year 2024 Volume: 11 Issue: 2

Cite

APA Yetgin, A. (2024). Investigating medicinal plants for antimicrobial benefits in a changing climate. International Journal of Secondary Metabolite, 11(2), 364-377. https://doi.org/10.21448/ijsm.1279531
International Journal of Secondary Metabolite

e-ISSN: 2148-6905