Abstract
Amaç:
Son yıllarda 3D yazıcı
teknolojlerinin tıbbın cerrahi branşlarında kullanımına yönelik çalışmalar
artmıştır. Bu çalışmada da yapılmış hayvan çalışmaları ve klinik deneyler
derlenerek bu teknolojinin gelecekteki kullanımına yönelik bir perspektif
sunulması amaçlandı.
Metod: Ekim 2019'a
kadar ‟ ClinicalTrials.gov ”da yayınlanan klinik deneyler ve ‟ PubMed ”de
yayınlanan hayvan çalışmaları bu derlemeye dahil edilmiştir. Bu çalışmalar
istatiksel olarak değerlendirilerek kategorilere,yıllara ve ülkelere göre
sınıflandırılmıştır.
Sonuç:
Bu kapsamda 70 adet klinik deney ve 159
adet hayvan çalışması değerlendirilmiştir. Klinik deneyler 14 ülkede , hayvan
çalışmaları 22 ülkede gerçekleştirilmiştir. Klinik çalışmalara toplam 4746
hasta dahil edilmiştir. Hem hayvan çalışmalarında hem de klinik deneylerde en
çok çalışma ortopedi alanında yapılmıştır.
Çıkarımlar:
Yaptığımız çalışma bir kez daha
göstermiştir ki, 3D yazıcı teknolojileri cerrahiyle alakalı tıbbi branşlar
başta olmak üzere tıbbın birçok branşında kullanıma girmiştir. Gelecek yıllarda
yapılan çalışmaların artmasıyla birlikte bu teknolojinin tıbbın her branşında
kullanımının yaygınlaşacağını bu sayede hastalara uygulanacak tedavi
protokollerinin de geliştirileceğini ön görüyoruz.
Keywords
References
- 1. Vukicevic M, Mosadegh B, Min JK, Little SH. Cardiac 3D printing and its future directions. JACC Cardiovasc Imaging. 2017 Feb; 10(2): 171-184. doi: 10.1016/j.jcmg.2016.12.001.
- 2. Mitsuoka H, Terai Y, Miyano Y, Naitou T, Tanai J, Kawaguchi S, Goto S, Miura Y,Nakai M, Yamazaki F. Preoperative Planning for Physician-Modified Endografts Using a Three-Dimensional Printer. Ann Vasc Dis. 2019 Sep 25;12(3):334-339. doi: 10.3400/avd.ra.19-00062.
- 3. Witowski J, Sitkowski M, Zuzak T, Coles-Black J, Chuen J, Major P, Pdziwiatr M. From ideas to long-term studies: 3D printing clinical trials review. Int J Comput Assist Radiol Surg. 2018; 13(9): 1473-1478. doi: 10.1007/s11548-018-1793-8
- 4. Marti P, Lampus F, Benevento D, Setacci C. Trends in use of 3D printing in vascular surgery: a survey. Int Angiol. 2019 Oct;38(5):418-424. doi: 10.23736/S0392-9590.19.04148-8.
- 5. Zopf DA, Mitsak AG, Flanagan CL, Wheeler M, Green GE, Hollister SJ. Computer aided-designed, 3-dimensionally printed porous tissue bioscaffolds for craniofacial soft tissue reconstruction. Otolaryngol Head Neck Surg. 2015;152(1):57-62 doi: 10.1177/0194599814552065
- 6. Skelley NW, Smith MJ, Ma R, Cook JL. Three-dimensional Printing Technology in Orthopaedics. J Am Acad Orthop Surg. 2019 Jul 1. doi: 10.5435/JAAOS-D-18-00746.
- 7. Martelli N, Serrano C, van den Brink H, Pineau J, Prognon P, Borget I, El Batti S. Advantages and disadvantages of 3-dimensional printing in surgery: A systematic review. Surgery. 2016; 159(6): 1485-1500. doi: 10.1016/j.surg.2015.12.017
Abstract
Purpose: In recent years, the use of 3D printing
technologies in surgery has increased. We aimed to provide a perspective on the
future of the use of this technology in surgery by compiling animal and
clinical studies.
Methods: The clinical
studies published in the ‟ ClinicalTrials.gov ”, and the animal studies in
‟ PubMed ” were included in this review. We have included studies published
until October 2019 in our review and conducted a statistical evaluation by
classifying into categories, years, and countries.
Results: We evaluated
the results of 70 clinical trials and 159 animal studies which were in
compliance with our criteria. Animal studies were registered in 22 countries. 70
clinical trials were registered in 14 countries. A total of 4746 people were
included in the clinical trials. In both animal studies (47.16%) and clinical
trials (30.00%), most of the studies were performed in the field of
orthopedics.
Conclusions:
Our study has shown once
again that 3D printing technologies are used in many fields of medicine especially
surgery-related branches.With the increasing number of research in the
following years, we anticipate that this technology will become widespread in
every field of medicine and will improve treatment protocols applied to
patients.
Keywords
References
- 1. Vukicevic M, Mosadegh B, Min JK, Little SH. Cardiac 3D printing and its future directions. JACC Cardiovasc Imaging. 2017 Feb; 10(2): 171-184. doi: 10.1016/j.jcmg.2016.12.001.
- 2. Mitsuoka H, Terai Y, Miyano Y, Naitou T, Tanai J, Kawaguchi S, Goto S, Miura Y,Nakai M, Yamazaki F. Preoperative Planning for Physician-Modified Endografts Using a Three-Dimensional Printer. Ann Vasc Dis. 2019 Sep 25;12(3):334-339. doi: 10.3400/avd.ra.19-00062.
- 3. Witowski J, Sitkowski M, Zuzak T, Coles-Black J, Chuen J, Major P, Pdziwiatr M. From ideas to long-term studies: 3D printing clinical trials review. Int J Comput Assist Radiol Surg. 2018; 13(9): 1473-1478. doi: 10.1007/s11548-018-1793-8
- 4. Marti P, Lampus F, Benevento D, Setacci C. Trends in use of 3D printing in vascular surgery: a survey. Int Angiol. 2019 Oct;38(5):418-424. doi: 10.23736/S0392-9590.19.04148-8.
- 5. Zopf DA, Mitsak AG, Flanagan CL, Wheeler M, Green GE, Hollister SJ. Computer aided-designed, 3-dimensionally printed porous tissue bioscaffolds for craniofacial soft tissue reconstruction. Otolaryngol Head Neck Surg. 2015;152(1):57-62 doi: 10.1177/0194599814552065
- 6. Skelley NW, Smith MJ, Ma R, Cook JL. Three-dimensional Printing Technology in Orthopaedics. J Am Acad Orthop Surg. 2019 Jul 1. doi: 10.5435/JAAOS-D-18-00746.
- 7. Martelli N, Serrano C, van den Brink H, Pineau J, Prognon P, Borget I, El Batti S. Advantages and disadvantages of 3-dimensional printing in surgery: A systematic review. Surgery. 2016; 159(6): 1485-1500. doi: 10.1016/j.surg.2015.12.017
Details
| Primary Language | English |
|---|---|
| Subjects | Biomaterial |
| Journal Section | Review Articles |
| Authors | |
| Publication Date | April 30, 2020 |
| Submission Date | November 11, 2019 |
| Published in Issue | Year 2020 Volume: 4 Issue: 1 |
Cite
International Journal of 3D Printing Technologies and Digital Industry is lisenced under Creative Commons Atıf-GayriTicari 4.0 Uluslararası Lisansı