Determination and monitoring of tetracycline and degradation products in livestock slaughterhouse wastewater treatment plant effluent

Murat Topal; Emine Işıl Arslan Topal; Erdal Öbek

doi:10.35860/iarej.1265230

Research Article

Determination and monitoring of tetracycline and degradation products in livestock slaughterhouse wastewater treatment plant effluent

Year 2023, Volume: 7 Issue: 2, 109 - 115, 15.08.2023

Murat Topal Emine Işıl Arslan Topal Erdal Öbek

https://doi.org/10.35860/iarej.1265230

Abstract

Aim of our study was the determination and monitoring of tetracycline (TC) and degradation products (DEP) in livestock slaughterhouse wastewater treatment plant (SWWTP) effluent. For this purpose, TC and DEP values in SWWTP were investigated. The concentrations of TC and DEP were monitored for 12 months. TC, 4-epitetracycline (ETC), 4-epianhydrotetracycline (EATC), anhydrotetracycline (ATC), and physicochemical parameters of pH, suspended solids (SS), BOD5, COD, and TP were calculated. The maximum TC concentration was determined as 1.68±0.08 µg/L in March and the minimum TC was 1.08±0.05 µg/L in January. The maximum ETC was 2.93±0.14 µg/L in March and April. The minimum ETC was 1.98±0.1 µg/L in January. EATC was 10.82±0.5 µg/L in September, and minimum EATC value was determined as 9.14±0.4 µg/L in March. The maximum ATC value was 8.62±0.4 µg/L in June and the lowest ATC value was 6.61±0.3 µg/L in September. Concentrations of TC and DEP detected in SWWTP effluent were listed in descending order as EATC> ATC> ETC> TC.

Keywords

Drug, Pollution, Removal, Slaughterhouse, Tetrcycline

References

1. Liu, L., C. Liu, J. Zheng, X. Huang, Z. Wang, Y. Liu, and G. Zhu, Elimination of veterinary antibiotics and antibiotic resistance genes from swine wastewater in the vertical flow constructed wetlands. Chemosphere, 2013. 91(8): p. 1088-1093.
2. Guarddon, M., J.M. Miranda, J.A. Rodríguez, B.I. Vázquez, A. Cepeda, and C.M. Franco, Real-time polymerase chain reaction for the quantitative detection of tetA and tetB bacterial tetracycline resistance genes in food. International Journal of Food Microbiology, 2011. 146(3): p. 284-289.
3. Kim, H.Y., J. Jeon, J. Hollender, S. Yu, and S.D. Kim, Aqueous and dietary bioaccumulation of antibiotic tetracycline in D. magna and its multigenerational transfer. Journal of Hazardous Materials, 2014. 279: p. 428-435.
4. Halling-Sørensen, B., Algal toxicity of antibacterial agents used in intensive farming. Chemosphere, 2000. 40(7): p. 731-739.
5. Watkinson, A.J., E.J. Murby, and S.D. Costanzo, Removal of antibiotics in conventional and advanced wastewater treatment: implications for environmental discharge and wastewater recycling. Water Research, 2007. 41(18): p. 4164–4176.
6. Topal, M. and E.I. Arslan Topal, Occurrence and fate of tetracycline and degradation products in municipal biological wastewater treatment plant and transport of them in surface water. Environmental Monitoring Assessment, 2015. 187(12): p. 1-9.
7. Kemper, N., Veterinary antibiotics in the aquatic and terrestrial environment. Ecological Indicators, 2008. 8(1): p. 1-13.
8. Kümmerer, K., A. Al-Ahmad, and V. Mersch-Sundermann, Biodegradability of some antibiotics, elimination of the genotoxicity and affection of wastewater bacteria in a simple test. Chemosphere, 2000. 40(7): p. 701-707.
9. Langhammer, J.P., Untersuchungen zum Verbleib antimikrobiell wirsamer Arzneistoff-Rückstände in Gülle und im landwirtschaftlichen Umfeld. PhD-Dissertation, 1989, Universität Bonn: Germany. p.1-28.
10. Tritt, W.P. and F. Schuchardt, Materials flow and possibilities of treating liquid and solid wastes from slaughterhouses in Germany. A review. Bioresource Technology, 1992. 41(3): p. 235-245.
11. Bustillo-Lecompte, C.F. and M. Mehrvar, Slaughterhouse wastewater characteristics, treatment, and management in the meat processing industry: A review on trends and advances. Journal of Environmental Management, 2015. 161(15): p. 287-302.
12. Arslan Topal, E.I., Uptake of tetracycline and metabolites in Phragmites australis exposed to treated poultry slaughterhouse wastewaters. Ecological Engineering, 2015. 83(1): p. 233-238.
13. Hu, Y., H. Cheng, and S. Tao, Environmental and human health challenges of industrial livestock and poultry farming in China and their mitigation. Environment International, 2017. 107: p. 111-130.
14. Cavenati, S., P.N. Carvalho, C.M.R. Almeida, M.C.P. Basto, and M.T.S.D. Vasconcelos, Simultaneous determination of several veterinary pharmaceuticals in effluents from urban, livestock and slaughterhouse wastewater treatment plants using a simple chromatographic method. Water Science & Technology, 2012. 66(3): p. 603-611.
15. Shao, B., D. Chen, J. Zhang, Y. Wu, and C. Sun, Determination of 76 pharmaceutical drugs by liquid chromatography–tandem mass spectrometry in slaughterhouse wastewater. Journal of Chromatography A, 2009. 1216(47): p. 8312-8318.
16. Wang, Z., M. Xiang, B. Huo, J. Wang, L. Yang, W. Ma, J. Qi, Y. Wang, Z. Zhu, and F. Meng, A novel ZnO/CQDs/PVDF piezoelectric system for efficiently degradation of antibiotics by using water flow energy in pipeline: Performance and mechanism. Nano Energy, 2023. 107: 108162.
17. Chen, Z., D. Ou, G. Gu, S. Gao, X. Li, C. Hu, X. Liang, and Y. Zhang, Removal of tetracycline from water by catalytic photodegradation combined with the microalga Scenedesmus obliquus and the responses of algal photosynthesis and transcription. Journal of Environmental Management, 2023. 326(Pt A): 116693.
18. Chopra, I. and M. Roberts, Tetracycline antibiotics: mode of action, applications, molecular biology, and epidemiology of bacterial resistance. Microbiology and Molecular Biology Reviews, 2001. 65(2): p. 232-260.
19. Zhang, W., B.S.M. Sturm, C.W. Knapp, and D.W. Graham, Accumulation of tetracycline resistance genes in aquatic biofilms due to periodic waste loadings from swine lagoons. Environmental Science and Technology, 2009. 43(20): p. 7643-7650.
20. Melo, R.T., A.L. Grazziotin, E.C.V. Júnior, R.R. Prado, E.P. Mendonça, G.P. Monteiro, P.A.B.M. Peres, and D.A. Rossi, Evolution of Campylobacter jejuni of poultry origin in Brazil. Food Microbiology, 2019. 82: p. 489-496.
21. Elazığ Report [cited 2023 28 January]; Available from: http://www.gencistihdami.net/Portals/0/rapor/Faal%201.1/Faal%201.1-ELAZIG%20Rapor.pdf
22. Jia, A., Y. Xiao, J. Hu, M. Asami, and S. Kunikane, Simultaneous determination of tetracyclines and their degradation products in environmental waters by liquid chromatography–electrospray tandem mass spectrometry. Journal of Chromatography A, 2009. 1216(22): p. 4655-4662.
23. Ben, W., Z.M. Qiang, C. Adams, H.P. Zhang, and L.P. Chen, Simultaneous determination of sulfonamides, tetracyclines and tiamulin in swine wastewater by solid-phase extraction and liquid chromatography–mass spectrometry. Journal of Chromatography A, 2008. 1202(2): p. 173–180.
24. Akbay, H.E.G., C. Akarsu, and H. Kumbur, Treatment of fruit juice concentrate wastewater by electrocoagulation: Optimization of COD removal. International Advanced Researches and Engineering Journal, 2018. 2(1): p. 053-057.
25. Topal Canbaz, G., N. Keklikcioğlu Çakmak, A. Eroğlu, and Ü. Açıkel, Removal of Acid Orange 74 from wastewater with TiO2 nanoparticle. International Advanced Researches and Engineering Journal, 2018. 3(1): p. 075-080.

Year 2023, Volume: 7 Issue: 2, 109 - 115, 15.08.2023

Murat Topal Emine Işıl Arslan Topal Erdal Öbek

https://doi.org/10.35860/iarej.1265230

Abstract

References

1. Liu, L., C. Liu, J. Zheng, X. Huang, Z. Wang, Y. Liu, and G. Zhu, Elimination of veterinary antibiotics and antibiotic resistance genes from swine wastewater in the vertical flow constructed wetlands. Chemosphere, 2013. 91(8): p. 1088-1093.
2. Guarddon, M., J.M. Miranda, J.A. Rodríguez, B.I. Vázquez, A. Cepeda, and C.M. Franco, Real-time polymerase chain reaction for the quantitative detection of tetA and tetB bacterial tetracycline resistance genes in food. International Journal of Food Microbiology, 2011. 146(3): p. 284-289.
3. Kim, H.Y., J. Jeon, J. Hollender, S. Yu, and S.D. Kim, Aqueous and dietary bioaccumulation of antibiotic tetracycline in D. magna and its multigenerational transfer. Journal of Hazardous Materials, 2014. 279: p. 428-435.
4. Halling-Sørensen, B., Algal toxicity of antibacterial agents used in intensive farming. Chemosphere, 2000. 40(7): p. 731-739.
5. Watkinson, A.J., E.J. Murby, and S.D. Costanzo, Removal of antibiotics in conventional and advanced wastewater treatment: implications for environmental discharge and wastewater recycling. Water Research, 2007. 41(18): p. 4164–4176.
6. Topal, M. and E.I. Arslan Topal, Occurrence and fate of tetracycline and degradation products in municipal biological wastewater treatment plant and transport of them in surface water. Environmental Monitoring Assessment, 2015. 187(12): p. 1-9.
7. Kemper, N., Veterinary antibiotics in the aquatic and terrestrial environment. Ecological Indicators, 2008. 8(1): p. 1-13.
8. Kümmerer, K., A. Al-Ahmad, and V. Mersch-Sundermann, Biodegradability of some antibiotics, elimination of the genotoxicity and affection of wastewater bacteria in a simple test. Chemosphere, 2000. 40(7): p. 701-707.
9. Langhammer, J.P., Untersuchungen zum Verbleib antimikrobiell wirsamer Arzneistoff-Rückstände in Gülle und im landwirtschaftlichen Umfeld. PhD-Dissertation, 1989, Universität Bonn: Germany. p.1-28.
10. Tritt, W.P. and F. Schuchardt, Materials flow and possibilities of treating liquid and solid wastes from slaughterhouses in Germany. A review. Bioresource Technology, 1992. 41(3): p. 235-245.
11. Bustillo-Lecompte, C.F. and M. Mehrvar, Slaughterhouse wastewater characteristics, treatment, and management in the meat processing industry: A review on trends and advances. Journal of Environmental Management, 2015. 161(15): p. 287-302.
12. Arslan Topal, E.I., Uptake of tetracycline and metabolites in Phragmites australis exposed to treated poultry slaughterhouse wastewaters. Ecological Engineering, 2015. 83(1): p. 233-238.
13. Hu, Y., H. Cheng, and S. Tao, Environmental and human health challenges of industrial livestock and poultry farming in China and their mitigation. Environment International, 2017. 107: p. 111-130.
14. Cavenati, S., P.N. Carvalho, C.M.R. Almeida, M.C.P. Basto, and M.T.S.D. Vasconcelos, Simultaneous determination of several veterinary pharmaceuticals in effluents from urban, livestock and slaughterhouse wastewater treatment plants using a simple chromatographic method. Water Science & Technology, 2012. 66(3): p. 603-611.
15. Shao, B., D. Chen, J. Zhang, Y. Wu, and C. Sun, Determination of 76 pharmaceutical drugs by liquid chromatography–tandem mass spectrometry in slaughterhouse wastewater. Journal of Chromatography A, 2009. 1216(47): p. 8312-8318.
16. Wang, Z., M. Xiang, B. Huo, J. Wang, L. Yang, W. Ma, J. Qi, Y. Wang, Z. Zhu, and F. Meng, A novel ZnO/CQDs/PVDF piezoelectric system for efficiently degradation of antibiotics by using water flow energy in pipeline: Performance and mechanism. Nano Energy, 2023. 107: 108162.
17. Chen, Z., D. Ou, G. Gu, S. Gao, X. Li, C. Hu, X. Liang, and Y. Zhang, Removal of tetracycline from water by catalytic photodegradation combined with the microalga Scenedesmus obliquus and the responses of algal photosynthesis and transcription. Journal of Environmental Management, 2023. 326(Pt A): 116693.
18. Chopra, I. and M. Roberts, Tetracycline antibiotics: mode of action, applications, molecular biology, and epidemiology of bacterial resistance. Microbiology and Molecular Biology Reviews, 2001. 65(2): p. 232-260.
19. Zhang, W., B.S.M. Sturm, C.W. Knapp, and D.W. Graham, Accumulation of tetracycline resistance genes in aquatic biofilms due to periodic waste loadings from swine lagoons. Environmental Science and Technology, 2009. 43(20): p. 7643-7650.
20. Melo, R.T., A.L. Grazziotin, E.C.V. Júnior, R.R. Prado, E.P. Mendonça, G.P. Monteiro, P.A.B.M. Peres, and D.A. Rossi, Evolution of Campylobacter jejuni of poultry origin in Brazil. Food Microbiology, 2019. 82: p. 489-496.
21. Elazığ Report [cited 2023 28 January]; Available from: http://www.gencistihdami.net/Portals/0/rapor/Faal%201.1/Faal%201.1-ELAZIG%20Rapor.pdf
22. Jia, A., Y. Xiao, J. Hu, M. Asami, and S. Kunikane, Simultaneous determination of tetracyclines and their degradation products in environmental waters by liquid chromatography–electrospray tandem mass spectrometry. Journal of Chromatography A, 2009. 1216(22): p. 4655-4662.
23. Ben, W., Z.M. Qiang, C. Adams, H.P. Zhang, and L.P. Chen, Simultaneous determination of sulfonamides, tetracyclines and tiamulin in swine wastewater by solid-phase extraction and liquid chromatography–mass spectrometry. Journal of Chromatography A, 2008. 1202(2): p. 173–180.
24. Akbay, H.E.G., C. Akarsu, and H. Kumbur, Treatment of fruit juice concentrate wastewater by electrocoagulation: Optimization of COD removal. International Advanced Researches and Engineering Journal, 2018. 2(1): p. 053-057.
25. Topal Canbaz, G., N. Keklikcioğlu Çakmak, A. Eroğlu, and Ü. Açıkel, Removal of Acid Orange 74 from wastewater with TiO2 nanoparticle. International Advanced Researches and Engineering Journal, 2018. 3(1): p. 075-080.

There are 25 citations in total.

Details

Primary Language	English
Subjects	Environmental Engineering, Environmental and Sustainable Processes
Journal Section	Research Articles
Authors	Murat Topal 0000-0003-0222-5409 Emine Işıl Arslan Topal 0000-0003-0309-7787 Erdal Öbek 0000-0002-4595-572X
Early Pub Date	August 27, 2023
Publication Date	August 15, 2023
Submission Date	March 14, 2023
Acceptance Date	July 6, 2023
Published in Issue	Year 2023 Volume: 7 Issue: 2

Cite

APA	Topal, M., Arslan Topal, E. I., & Öbek, E. (2023). Determination and monitoring of tetracycline and degradation products in livestock slaughterhouse wastewater treatment plant effluent. International Advanced Researches and Engineering Journal, 7(2), 109-115. https://doi.org/10.35860/iarej.1265230
AMA	Topal M, Arslan Topal EI, Öbek E. Determination and monitoring of tetracycline and degradation products in livestock slaughterhouse wastewater treatment plant effluent. Int. Adv. Res. Eng. J. August 2023;7(2):109-115. doi:10.35860/iarej.1265230
Chicago	Topal, Murat, Emine Işıl Arslan Topal, and Erdal Öbek. “Determination and Monitoring of Tetracycline and Degradation Products in Livestock Slaughterhouse Wastewater Treatment Plant Effluent”. International Advanced Researches and Engineering Journal 7, no. 2 (August 2023): 109-15. https://doi.org/10.35860/iarej.1265230.
EndNote	Topal M, Arslan Topal EI, Öbek E (August 1, 2023) Determination and monitoring of tetracycline and degradation products in livestock slaughterhouse wastewater treatment plant effluent. International Advanced Researches and Engineering Journal 7 2 109–115.
IEEE	M. Topal, E. I. Arslan Topal, and E. Öbek, “Determination and monitoring of tetracycline and degradation products in livestock slaughterhouse wastewater treatment plant effluent”, Int. Adv. Res. Eng. J., vol. 7, no. 2, pp. 109–115, 2023, doi: 10.35860/iarej.1265230.
ISNAD	Topal, Murat et al. “Determination and Monitoring of Tetracycline and Degradation Products in Livestock Slaughterhouse Wastewater Treatment Plant Effluent”. International Advanced Researches and Engineering Journal 7/2 (August 2023), 109-115. https://doi.org/10.35860/iarej.1265230.
JAMA	Topal M, Arslan Topal EI, Öbek E. Determination and monitoring of tetracycline and degradation products in livestock slaughterhouse wastewater treatment plant effluent. Int. Adv. Res. Eng. J. 2023;7:109–115.
MLA	Topal, Murat et al. “Determination and Monitoring of Tetracycline and Degradation Products in Livestock Slaughterhouse Wastewater Treatment Plant Effluent”. International Advanced Researches and Engineering Journal, vol. 7, no. 2, 2023, pp. 109-15, doi:10.35860/iarej.1265230.
Vancouver	Topal M, Arslan Topal EI, Öbek E. Determination and monitoring of tetracycline and degradation products in livestock slaughterhouse wastewater treatment plant effluent. Int. Adv. Res. Eng. J. 2023;7(2):109-15.

Download Cover Image

Article Files

Full Text

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI.

Open Access Journal System - BOAI