Research Article
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Year 2024, Volume: 8 Issue: 1, 14 - 18, 31.03.2024

Mertcan Karadeniz Temel Kan Bakır Sabri Ünal

https://doi.org/10.30516/bilgesci.1385144

Abstract

References

  • Aoki, M., Tan, M., Fukushima, A., Hieda, T., Kubo, S., Takabayashi, M., Ono, K., Mikami, Y. (1993). Antiviral Substances with Systemic Effects Produced by Basidiomycetes such as Fomes fomentarius. Biosci Biotechnol Biochem. 57(2):278-82. doi: 10.1271/bbb.57.278.
  • Bojin, L. A., Serb, A. F., Pascariu, M. C., Moaca, A., Kostici, R., Purcărea, V. L., Penescu, M., Ivan, M.V., Georgescu, M., Sisu, E. (2020). Assessment of antioxidant properties of different Fomes fomentarius extracts. Farmacia, 68(2), 322-328. 10.31925/farmacia.2020.2.18
  • Bozdogan, A., Ulukanlı, Z., Bozok, F., Eker, T., Doğan, H.H., Büyükalaca, S., (2018). Antioxidant Potential of Lactarius Deliciosus and Pleurotus ostreatus from Amanos Mountains. Adv. Life Sci. 5(3): 113-120.
  • Chandler, S. F., Dodds, J. H. (1983). The effect of phosphate, nitrogen and sucrose on the production of phenolics and solasodine in callus cultures of Solanum laciniatum. Plant Cell Reports, 2(4), 205-208. DOI: 10.1007/BF00270105
  • Chang, S.T., Miles, P.G. (2008). Mushrooms: Cultivation, Nutritional Value, Medicinal Effect, and Environmental Impact, 2nd ed.; CRC Press: Boca Raton, FL, USA.
  • Chen, W., Zhao, Z., Chen, S.F., Li, Y.Q. (2008). Optimization for the production of exopolysaccharide from Fomes fomentarius in submerged culture and its antitumor effect in vitro. Bioresour Technol. 99(8):3187-94. doi: 10.1016/j.biortech.2007.05.049.
  • Elkhateeb, W.A., Elnahas, M.O., Thomas, P.W., Daba, G.M. (2020). Fomes fomentarius and Polyporus squamosus Models of MarvelMedicinal Mushrooms. Biomed Res Rev. 3(1):119. doi: 10.31021/brr.20203119
  • Erbiai, E. H., da Silva, L. P., Saidi, R., Lamrani, Z., Esteves da Silva, J. C.G., Maouni, A. (2021). Chemical composition, bioactive compounds, and antioxidant activity of two wild edible mushrooms Armillaria mellea and Macrolepiota procera from two countries (Morocco and Portugal). Biomolecules, 11(4):575. doi: 10.3390/biom11040575.
  • Frankel, E. N., Meyer, A. S. (2000). The problems of using one dimensional methods to evaluate multifunctional food and biological antioxidants. Journal of the Science of Food and Agriculture, 80(13), 1925-1941. DOI: 10.1002/1097-0010(200010)80:13
  • Fulgoni, V.L. 3rd, Agarwal, S. (2021). Nutritional impact of adding a serving of mushrooms on usual intakes and nutrient adequacy using National Health and Nutrition Examination Survey 2011-2016 data. Food Sci Nutr. 9(3):1504-1511. doi: 10.1002/fsn3.2120.
  • González-Palma, I., Escalona-Buendía, H.B., Ponce-Alquicira, E., Téllez-Téllez, M., Gupta, V.K., Díaz-Godínez, G., Soriano-Santos, J. (2016). Evaluation of the Antioxidant Activity of Aqueous and Methanol Extracts of Pleurotus ostreatus in Different Growth Stages. Front Microbiol. 7:1099. doi: 10.3389/fmicb.2016.01099.
  • Grienke, U., Zöll, M., Peintner, U., Rollinger, J.M. (2014) European medicinal polypores - A modern view on traditional uses. J. Ethnopharmacol. 154(3): 564-583. doi: 10.1016/j.jep.2014.04.030.
  • Gülçin, İ., Büyükokuroǧlu, M. E., Oktay, M., Küfrevioǧlu, Ö. İ. (2003). Antioxidant and analgesic activities of turpentine of Pinus nigra Arn. subsp. pallsiana (Lamb.) Holmboe. Journal of Ethnopharmacology, 86(1), 51-58. DOI: 10.1016/S0378-8741(03)00036-9
  • Kalaras, M.D., Richie, J.P., Calcagnotto, A., Beelman, R.B. (2017). Mushrooms: A rich source of the antioxidants ergothioneine and glutathione. Food Chem. 233:429-433. doi: 10.1016/j.foodchem.2017.04.109.
  • Kolundzic, M., Grozdanic, N.D., Dodevskac, M., Milenkovic, M., Sistoe, F., Mianie, A., Farronato, G., Kundakovic, T. (2016). Antibacterial and cytotoxic activities of wild mushroom Fomes fomentarius (L.) Fr., Polyporaceae. Ind Crops Prod., 79: 110-115. DOI: 10.1016/j.indcrop.2015.10.030
  • Kolniak-Ostek, J., Oszmiański, J., Szyjka, A., Moreira, H., Barg, E. (2022). Anticancer and Antioxidant Activities in Ganoderma lucidum Wild Mushrooms in Poland, as Well as Their Phenolic and Triterpenoid Compounds. Int J Mol Sci. 23(16):9359. doi: 10.3390/ijms23169359.
  • Kozarski, M., Klaus, A., Jakovljevic, D., Todorovic, N., Vunduk, J., Petrović, P., Niksic, M., Vrvic, M.M., van Griensven, L. (2015). Antioxidants of Edible Mushrooms. Molecules. 20(10):19489-525. doi: 10.3390/molecules201019489.
  • Lee, D. H., Kim, J. H., Park, J. S., Choi, Y. J., Lee, J. S. (2004). Isolation and characterization of a novel angiotensin I-converting enzyme inhibitory peptide derived from the edible mushroom Tricholoma giganteum. Peptides, 25(4), 621-627. DOI: 10.1016/j.peptides.2004.01.015
  • Li, Q.Z., Zheng, Y.Z., Zhou, X.W. (2019). Fungal immunomodulatory proteins: characteristic, potential antitumor activities and their molecular mechanisms. Drug Discov. Today ; 24(1), 307-314).
  • Mohammadifar, S., Fallahi Gharaghoz, S., Asef Shayan, M.R., Vaziri, A. (2020). Comparison between antioxidant activity and bioactive compounds of Ganoderma applanatum (Pers.) Pat. and Ganoderma lucidum (Curt.) P. Karst from Iran. Iranian Journal of Plant Physiology, 11(1), 3417-3424.
  • Oviasogie, F. E., Akpaja, E. O., Gbona, K. C., Akonoafua, E. A. (2015). Antimicrobial properties of Ganoderma applanatum (Pers.) Pat. from Benin city, Nigeria. Nigerian Journal of Agriculture, Food and Environment, 11(3), 65-69.
  • Rahman, M.A., Abdullah, N., Aminudin, N. (2015). Antioxidative effects and inhibition of human low density lipoprotein oxidation in vitro of polyphenolic compounds in flammulina velutipes (golden needle mushroom). Oxid Med Cell Longev. 2015;2015: 403023. doi: 10.1155/2015/403023.
  • Slinkard, K., Singleton, V. L. (1977). Total phenol analysis: automation and comparison with manual methods. American Journal of Enology and Viticulture, 28(1), 49-55.
  • Suárez-Arroyo, I.J., Loperena-Alvarez, Y., Rosario-Acevedo, R., Martínez-Montemayor, M.M. (2017). Ganoderma spp.: A Promising Adjuvant Treatment for Breast Cancer. Medicines (Basel). 4(1):15. doi: 10.3390/medicines4010015.
  • Umeno, A., Biju, V., Yoshida, Y. (2017). In vivo ROS production and use of oxidative stressderived biomarkers to detect the onset of diseases such as Alzheimer's disease, Parkinson's disease, and diabetes. Free Radic. Res. 51 (4) 413–427. doi: 10.1080/10715762.2017.1315114.
  • Wasser, S. P. (2011). Current findings, future trends and unsolved problems in studies of medicinal mushrooms. Applied Microbiology and Biotechnology, 89(5):1323-1332. doi: 10.1007/s00253-010-3067-4.
  • Zhong-Hua, L., Xiao-Ge, H., Jin-Hui, Z., Le, HE. (2015). Liquid Fermentation of Ganoderma applanatum and Antioxidant Activity of Exopolysaccharides. Open Biomed Eng J. ;9:224-227. doi: 10.2174/1874120701509010224.

Investigation of the Antioxidant and Total Phenolic Substance of Fomes fomentarius and Ganoderma applanatum Mushrooms Showing Therapeutic Properties

Year 2024, Volume: 8 Issue: 1, 14 - 18, 31.03.2024

Mertcan Karadeniz Temel Kan Bakır Sabri Ünal

https://doi.org/10.30516/bilgesci.1385144

Abstract

Fomes fomentarius (Ffo) and Ganoderma applanatum (Gap), which are mushroom species used in traditional medicine in Far East Asia, are widely found in our country and attract great attention with their antioxidant properties. In this study, the antioxidant activities of these mushrooms grown in our country were examined spectrophotometrically using the DPPH method. The results were expressed as percent inhibition and also the IC50 values of the fungal samples were calculated using concentration equations. IC50 values for Ganoderma applanatum and Fomes fomentarius were found to be 0.515 and 0.463 mg/mL, respectively. Additionally, total phenolic substances were analyzed by the Folin-Ciocalteu Method. Phenol content in methanolic extracts expressed in gallic acid equivalents (GAE) was found to be 8,447 and 10,300 mg/L for Ganoderma applanatum and Fomes fomentarius, respectively. In this study, it was determined that both types of mushrooms are valuable in terms of both their phenolic content and antioxidant properties.

Keywords

Fomes fomentarius (Ffo) Ganoderma applanatum (Gap) Total phenolic substances DPPH method

References

  • Aoki, M., Tan, M., Fukushima, A., Hieda, T., Kubo, S., Takabayashi, M., Ono, K., Mikami, Y. (1993). Antiviral Substances with Systemic Effects Produced by Basidiomycetes such as Fomes fomentarius. Biosci Biotechnol Biochem. 57(2):278-82. doi: 10.1271/bbb.57.278.
  • Bojin, L. A., Serb, A. F., Pascariu, M. C., Moaca, A., Kostici, R., Purcărea, V. L., Penescu, M., Ivan, M.V., Georgescu, M., Sisu, E. (2020). Assessment of antioxidant properties of different Fomes fomentarius extracts. Farmacia, 68(2), 322-328. 10.31925/farmacia.2020.2.18
  • Bozdogan, A., Ulukanlı, Z., Bozok, F., Eker, T., Doğan, H.H., Büyükalaca, S., (2018). Antioxidant Potential of Lactarius Deliciosus and Pleurotus ostreatus from Amanos Mountains. Adv. Life Sci. 5(3): 113-120.
  • Chandler, S. F., Dodds, J. H. (1983). The effect of phosphate, nitrogen and sucrose on the production of phenolics and solasodine in callus cultures of Solanum laciniatum. Plant Cell Reports, 2(4), 205-208. DOI: 10.1007/BF00270105
  • Chang, S.T., Miles, P.G. (2008). Mushrooms: Cultivation, Nutritional Value, Medicinal Effect, and Environmental Impact, 2nd ed.; CRC Press: Boca Raton, FL, USA.
  • Chen, W., Zhao, Z., Chen, S.F., Li, Y.Q. (2008). Optimization for the production of exopolysaccharide from Fomes fomentarius in submerged culture and its antitumor effect in vitro. Bioresour Technol. 99(8):3187-94. doi: 10.1016/j.biortech.2007.05.049.
  • Elkhateeb, W.A., Elnahas, M.O., Thomas, P.W., Daba, G.M. (2020). Fomes fomentarius and Polyporus squamosus Models of MarvelMedicinal Mushrooms. Biomed Res Rev. 3(1):119. doi: 10.31021/brr.20203119
  • Erbiai, E. H., da Silva, L. P., Saidi, R., Lamrani, Z., Esteves da Silva, J. C.G., Maouni, A. (2021). Chemical composition, bioactive compounds, and antioxidant activity of two wild edible mushrooms Armillaria mellea and Macrolepiota procera from two countries (Morocco and Portugal). Biomolecules, 11(4):575. doi: 10.3390/biom11040575.
  • Frankel, E. N., Meyer, A. S. (2000). The problems of using one dimensional methods to evaluate multifunctional food and biological antioxidants. Journal of the Science of Food and Agriculture, 80(13), 1925-1941. DOI: 10.1002/1097-0010(200010)80:13
  • Fulgoni, V.L. 3rd, Agarwal, S. (2021). Nutritional impact of adding a serving of mushrooms on usual intakes and nutrient adequacy using National Health and Nutrition Examination Survey 2011-2016 data. Food Sci Nutr. 9(3):1504-1511. doi: 10.1002/fsn3.2120.
  • González-Palma, I., Escalona-Buendía, H.B., Ponce-Alquicira, E., Téllez-Téllez, M., Gupta, V.K., Díaz-Godínez, G., Soriano-Santos, J. (2016). Evaluation of the Antioxidant Activity of Aqueous and Methanol Extracts of Pleurotus ostreatus in Different Growth Stages. Front Microbiol. 7:1099. doi: 10.3389/fmicb.2016.01099.
  • Grienke, U., Zöll, M., Peintner, U., Rollinger, J.M. (2014) European medicinal polypores - A modern view on traditional uses. J. Ethnopharmacol. 154(3): 564-583. doi: 10.1016/j.jep.2014.04.030.
  • Gülçin, İ., Büyükokuroǧlu, M. E., Oktay, M., Küfrevioǧlu, Ö. İ. (2003). Antioxidant and analgesic activities of turpentine of Pinus nigra Arn. subsp. pallsiana (Lamb.) Holmboe. Journal of Ethnopharmacology, 86(1), 51-58. DOI: 10.1016/S0378-8741(03)00036-9
  • Kalaras, M.D., Richie, J.P., Calcagnotto, A., Beelman, R.B. (2017). Mushrooms: A rich source of the antioxidants ergothioneine and glutathione. Food Chem. 233:429-433. doi: 10.1016/j.foodchem.2017.04.109.
  • Kolundzic, M., Grozdanic, N.D., Dodevskac, M., Milenkovic, M., Sistoe, F., Mianie, A., Farronato, G., Kundakovic, T. (2016). Antibacterial and cytotoxic activities of wild mushroom Fomes fomentarius (L.) Fr., Polyporaceae. Ind Crops Prod., 79: 110-115. DOI: 10.1016/j.indcrop.2015.10.030
  • Kolniak-Ostek, J., Oszmiański, J., Szyjka, A., Moreira, H., Barg, E. (2022). Anticancer and Antioxidant Activities in Ganoderma lucidum Wild Mushrooms in Poland, as Well as Their Phenolic and Triterpenoid Compounds. Int J Mol Sci. 23(16):9359. doi: 10.3390/ijms23169359.
  • Kozarski, M., Klaus, A., Jakovljevic, D., Todorovic, N., Vunduk, J., Petrović, P., Niksic, M., Vrvic, M.M., van Griensven, L. (2015). Antioxidants of Edible Mushrooms. Molecules. 20(10):19489-525. doi: 10.3390/molecules201019489.
  • Lee, D. H., Kim, J. H., Park, J. S., Choi, Y. J., Lee, J. S. (2004). Isolation and characterization of a novel angiotensin I-converting enzyme inhibitory peptide derived from the edible mushroom Tricholoma giganteum. Peptides, 25(4), 621-627. DOI: 10.1016/j.peptides.2004.01.015
  • Li, Q.Z., Zheng, Y.Z., Zhou, X.W. (2019). Fungal immunomodulatory proteins: characteristic, potential antitumor activities and their molecular mechanisms. Drug Discov. Today ; 24(1), 307-314).
  • Mohammadifar, S., Fallahi Gharaghoz, S., Asef Shayan, M.R., Vaziri, A. (2020). Comparison between antioxidant activity and bioactive compounds of Ganoderma applanatum (Pers.) Pat. and Ganoderma lucidum (Curt.) P. Karst from Iran. Iranian Journal of Plant Physiology, 11(1), 3417-3424.
  • Oviasogie, F. E., Akpaja, E. O., Gbona, K. C., Akonoafua, E. A. (2015). Antimicrobial properties of Ganoderma applanatum (Pers.) Pat. from Benin city, Nigeria. Nigerian Journal of Agriculture, Food and Environment, 11(3), 65-69.
  • Rahman, M.A., Abdullah, N., Aminudin, N. (2015). Antioxidative effects and inhibition of human low density lipoprotein oxidation in vitro of polyphenolic compounds in flammulina velutipes (golden needle mushroom). Oxid Med Cell Longev. 2015;2015: 403023. doi: 10.1155/2015/403023.
  • Slinkard, K., Singleton, V. L. (1977). Total phenol analysis: automation and comparison with manual methods. American Journal of Enology and Viticulture, 28(1), 49-55.
  • Suárez-Arroyo, I.J., Loperena-Alvarez, Y., Rosario-Acevedo, R., Martínez-Montemayor, M.M. (2017). Ganoderma spp.: A Promising Adjuvant Treatment for Breast Cancer. Medicines (Basel). 4(1):15. doi: 10.3390/medicines4010015.
  • Umeno, A., Biju, V., Yoshida, Y. (2017). In vivo ROS production and use of oxidative stressderived biomarkers to detect the onset of diseases such as Alzheimer's disease, Parkinson's disease, and diabetes. Free Radic. Res. 51 (4) 413–427. doi: 10.1080/10715762.2017.1315114.
  • Wasser, S. P. (2011). Current findings, future trends and unsolved problems in studies of medicinal mushrooms. Applied Microbiology and Biotechnology, 89(5):1323-1332. doi: 10.1007/s00253-010-3067-4.
  • Zhong-Hua, L., Xiao-Ge, H., Jin-Hui, Z., Le, HE. (2015). Liquid Fermentation of Ganoderma applanatum and Antioxidant Activity of Exopolysaccharides. Open Biomed Eng J. ;9:224-227. doi: 10.2174/1874120701509010224.
There are 27 citations in total.

Details

Primary Language English
Subjects Forest Biodiversity, Forestry Sciences (Other)
Journal Section Research Articles
Authors

Mertcan Karadeniz 0000-0002-3627-9424

Temel Kan Bakır 0000-0002-7447-1468

Sabri Ünal 0000-0002-3026-0597

Early Pub Date March 31, 2024
Publication Date March 31, 2024
Submission Date November 2, 2023
Acceptance Date February 5, 2024
Published in Issue Year 2024 Volume: 8 Issue: 1

Cite

APA Karadeniz, M., Bakır, T. K., & Ünal, S. (2024). Investigation of the Antioxidant and Total Phenolic Substance of Fomes fomentarius and Ganoderma applanatum Mushrooms Showing Therapeutic Properties. Bilge International Journal of Science and Technology Research, 8(1), 14-18. https://doi.org/10.30516/bilgesci.1385144
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